Kooperativer Bibliotheksverbund

UID:

Umfang: 1 Online-Ressource (xxxi, 480 Seiten) : , Illustrationen.

Ausgabe: Second edition

ISBN: 978-0-12-810421-7 , 0-12-810421-X , 978-0-12-810420-0 , 0-12-810420-1

Inhalt: The Complement FactsBook, Second Edition, provides in-depth insights and an overview of the components of the complement system. This new edition highlights the use of newly recommended complement nomenclature, covering new pathways and proteins and adding information on mouse homologs. It is a completely revised and updated edition containing entries on all components of the complement system, and is an excellent source of one-stop shopping for complement information and references. It is the most convenient compilation of biochemical, biological and molecular biology for complementologists and those new in the field. This new edition is expanded to include relevant updates and topics that have evolved since the last edition was published, including C1q and Lectins, C3 Family, Serine Proteases, Serum Regulators of Complement Activation, Cell Surface Proteins, and Terminal Pathway Proteins. Domain Structure diagrams are incorporated to clearly illustrate the relationships between all the complement proteins, both within families and between families. Introduces complement function, simply described for each functionIncludes the cDNA sequences that are marked with intron/exon boundaries, facilitating genetic studiesPresents detailed structural information, including cDNA and gene structure for all proteinsIncorporates domain structures diagrams, which beautifully illustrate the relationship between all the complement proteins, both within, and between, families

Anmerkung: Includes index

Sprache: Englisch

Fachgebiete: Biologie

URL: Volltext  (URL des Erstveröffentlichers)

UID:

Umfang: xxxi, 480 Seiten : , Illustrationen.

Ausgabe: second edition

ISBN: 978-0-12-810420-0

Sprache: Englisch

Fachgebiete: Biologie

UID:

Umfang: 1 Online-Ressource (xxxi, 480 Seiten) : , Illustrationen.

Ausgabe: Second edition

ISBN: 978-0-12-810421-7 , 0-12-810421-X , 978-0-12-810420-0 , 0-12-810420-1

Inhalt: The Complement FactsBook, Second Edition, provides in-depth insights and an overview of the components of the complement system. This new edition highlights the use of newly recommended complement nomenclature, covering new pathways and proteins and adding information on mouse homologs. It is a completely revised and updated edition containing entries on all components of the complement system, and is an excellent source of one-stop shopping for complement information and references. It is the most convenient compilation of biochemical, biological and molecular biology for complementologists and those new in the field. This new edition is expanded to include relevant updates and topics that have evolved since the last edition was published, including C1q and Lectins, C3 Family, Serine Proteases, Serum Regulators of Complement Activation, Cell Surface Proteins, and Terminal Pathway Proteins. Domain Structure diagrams are incorporated to clearly illustrate the relationships between all the complement proteins, both within families and between families. Introduces complement function, simply described for each functionIncludes the cDNA sequences that are marked with intron/exon boundaries, facilitating genetic studiesPresents detailed structural information, including cDNA and gene structure for all proteinsIncorporates domain structures diagrams, which beautifully illustrate the relationship between all the complement proteins, both within, and between, families

Anmerkung: Includes index

Sprache: Englisch

Fachgebiete: Biologie

URL: Volltext  (URL des Erstveröffentlichers)

UID:

Umfang: 1 Online-Ressource (xxxi, 480 Seiten) : , Illustrationen.

Ausgabe: Second edition

ISBN: 978-0-12-810421-7 , 0-12-810421-X , 978-0-12-810420-0 , 0-12-810420-1

Inhalt: The Complement FactsBook, Second Edition, provides in-depth insights and an overview of the components of the complement system. This new edition highlights the use of newly recommended complement nomenclature, covering new pathways and proteins and adding information on mouse homologs. It is a completely revised and updated edition containing entries on all components of the complement system, and is an excellent source of one-stop shopping for complement information and references. It is the most convenient compilation of biochemical, biological and molecular biology for complementologists and those new in the field. This new edition is expanded to include relevant updates and topics that have evolved since the last edition was published, including C1q and Lectins, C3 Family, Serine Proteases, Serum Regulators of Complement Activation, Cell Surface Proteins, and Terminal Pathway Proteins. Domain Structure diagrams are incorporated to clearly illustrate the relationships between all the complement proteins, both within families and between families. Introduces complement function, simply described for each functionIncludes the cDNA sequences that are marked with intron/exon boundaries, facilitating genetic studiesPresents detailed structural information, including cDNA and gene structure for all proteinsIncorporates domain structures diagrams, which beautifully illustrate the relationship between all the complement proteins, both within, and between, families

Anmerkung: Includes index

Sprache: Englisch

Fachgebiete: Biologie

URL: Volltext  (URL des Erstveröffentlichers)

UID:

Umfang: 1 online resource (514 pages) : , illustrations (some color), tables

Ausgabe: Second edition.

ISBN: 0-12-810420-1 , 0-12-810421-X

Anmerkung: Front Cover -- The Complement FactsBook -- The Complement FactsBook -- Copyright -- Contents -- List of Contributors -- Preface -- 1 - Introduction -- AIMS AND SCOPE OF THE BOOK -- ORGANISATION OF THE DATA -- Other Names -- Physicochemical Properties -- Structure -- Function -- Degradation Pathway -- Tissue Distribution -- Regulation of Expression -- Human Protein Sequence -- Protein Modules -- Chromosomal Location -- cDNA Sequence -- Genomic Structure -- Accession Numbers -- Deficiency -- Polymorphic Variants -- Mutant Animals -- REFERENCE -- 2 - The Complement System -- HISTORICAL PERSPECTIVE -- MODULAR STRUCTURE OF THE COMPONENTS -- The Collectins -- Serine Proteases -- C3 Family -- Terminal Pathway -- Regulatory Proteins -- The Leucocyte Receptors -- PATHWAYS -- Classical Pathway -- Lectin Pathway -- Alternative Pathway -- Terminal Pathway -- REFERENCES -- I - Collectins -- 3 - C1q -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- DEGRADATION PATHWAY -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- FURTHER READING -- 4 - Mannose-Binding Lectin -- OTHER NAMES OF MANNOSE-BINDING LECTIN -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 5 - Ficolins -- OTHER NAMES FOR FICOLINS -- PHYSICOCHEMICAL PROPERTIES -- FICOLIN-1 -- FICOLIN-2 -- FICOLIN-3 -- STRUCTURE -- FUNCTION -- Lectin and Binding Activities -- Binding of Ficolins to Microorganisms -- Lectin Pathway Activation. , Cross Talk and Collaboration of Ficolins With Noncomplement Proteins -- Roles in Homeostasis -- TISSUE DISTRIBUTION -- PROTEIN SEQUENCE -- PROTEIN MODULES -- Splicing Variants of Ficolins -- CHROMOSOMAL LOCATION -- CDNA SEQUENCE -- GENOMIC STRUCTURE -- Accession Numbers -- POLYMORPHIC VARIANTS -- FICOLIN-DEFICIENT MOUSE -- REFERENCES -- 6 - The Collectins -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- CRYSTAL STRUCTURE -- FUNCTION -- Sugar Specificity -- Ligand Specificity -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- II - Serine Proteases -- 7 - MASP-1 -- PHYSICOCHEMICAL PROPERTIES -- Immature Protein -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION16 -- HUMAN CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 8 - MASP-2 -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION14 -- HUMAN CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 9 - MASP-3 -- PHYSICOCHEMICAL PROPERTIES -- Immature Protein -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION18 -- HUMAN CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 10 - C1r -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- 3D Structure -- FUNCTION. , TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE20-23 -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE22 -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 11 - C1s -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- 3D STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE26-28 -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE26 -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 12 - Factor D -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- DEGRADATION PATHWAY -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- CDNA SEQUENCES -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- FURTHER READING -- 13 - C2 -- PHYSIOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- EXPRESSION AND REGULATION -- PROTEIN SEQUENCE12,13 -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 14 - Factor B -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- PROTEIN SEQUENCES -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 15 - Factor I -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- PROTEIN SEQUENCES -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- CDNA SEQUENCES AND GENOMIC STRUCTURE. , POLYMORPHIC VARIANTS, DEFICIENCY AND DISEASE-RELATED SINGLE NUCLEOTIDE POLYMORPHISMS -- FI KNOCKOUT MICE -- REFERENCES -- III - C3 Family -- 16 - C3 -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- DEGRADATION PATHWAY -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 17 - C4 -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- PROTEIN SEQUENCE31 -- PROTEIN MODULES -- CHROMOSOMAL LOCATION33 -- CDNA SEQUENCE31,34 -- cDNA Sequence-Continued -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- Naturally Occurring C4 Deficiency -- C4 KNOCKOUT MOUSE PHENOTYPES -- REFERENCES -- 18 - C5 -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- DEGRADATION PATHWAY -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE3 -- HUMAN PROTEIN SEQUENCE-CONTINUED -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE -- HUMAN CDNA SEQUENCE-CONTINUED -- HUMAN CDNA SEQUENCE-CONTINUED -- Genomic Structure26,27 -- ACCESSION NUMBERS -- DEFICIENCY -- African-American Families28 -- Western Cape, South African Families29 -- Saudi Family30 -- Spanish Families31,32 -- Italian Family31 -- Brazilian Family33 -- Turkish Family34 -- Norwegian Family35 -- Danish Family35 -- Dutch Family36 -- Morocco Families37 -- POLYMORPHIC VARIANTS38 -- MUTANT ANIMALS -- REFERENCES -- IV - Terminal Pathway Components -- 19 - C6 -- PHYSIOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE1,2 -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE1,2. , GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 20 - C7 -- PHYSIOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE1 -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE1 -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 21 - C8 -- PHYSIOCHEMICAL PROPERTIES -- STRUCTURE -- CRYSTAL STRUCTURES -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- C8α19 -- C8β20, 21 -- C8γ22 -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE -- C8α19 -- C8β20, 21 -- C8γ22 -- GENOMIC STRUCTURE -- C8α24 -- C8β25 -- C8γ26 -- Polymorphic Variants -- MUTANT ANIMALS -- REFERENCES -- 22 - C9 -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE -- HUMAN CDNA SEQUENCE-CONTINUED -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- V - Regulatory Proteins -- 23 - C1 Inhibitor -- PHYSICOCHEMICAL PROPERTIES -- Immature Protein -- Mature Protein -- STRUCTURE -- FUNCTIONS -- DEGRADATION PATHWAY -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- CDNA SEQUENCE -- GENOMIC STRUCTURE -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 24 - C4b-Binding Protein -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- PROTEIN SEQUENCES -- PROTEIN MODULES -- CHROMOSOMAL LOCATION AND GENOMIC STRUCTURE -- CDNA SEQUENCES -- DEFICIENCY -- POLYMORPHIC VARIANTS AND DISEASE-RELATED SINGLE NUCLEOTIDE POLYMORPHISMS. , C4BP KNOCKOUT AND TRANSGENIC MICE.

Sprache: Englisch

UID:

Umfang: 1 online resource (514 pages) : , illustrations (some color), tables

Ausgabe: Second edition.

ISBN: 0-12-810420-1 , 0-12-810421-X

Anmerkung: Front Cover -- The Complement FactsBook -- The Complement FactsBook -- Copyright -- Contents -- List of Contributors -- Preface -- 1 - Introduction -- AIMS AND SCOPE OF THE BOOK -- ORGANISATION OF THE DATA -- Other Names -- Physicochemical Properties -- Structure -- Function -- Degradation Pathway -- Tissue Distribution -- Regulation of Expression -- Human Protein Sequence -- Protein Modules -- Chromosomal Location -- cDNA Sequence -- Genomic Structure -- Accession Numbers -- Deficiency -- Polymorphic Variants -- Mutant Animals -- REFERENCE -- 2 - The Complement System -- HISTORICAL PERSPECTIVE -- MODULAR STRUCTURE OF THE COMPONENTS -- The Collectins -- Serine Proteases -- C3 Family -- Terminal Pathway -- Regulatory Proteins -- The Leucocyte Receptors -- PATHWAYS -- Classical Pathway -- Lectin Pathway -- Alternative Pathway -- Terminal Pathway -- REFERENCES -- I - Collectins -- 3 - C1q -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- DEGRADATION PATHWAY -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- FURTHER READING -- 4 - Mannose-Binding Lectin -- OTHER NAMES OF MANNOSE-BINDING LECTIN -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 5 - Ficolins -- OTHER NAMES FOR FICOLINS -- PHYSICOCHEMICAL PROPERTIES -- FICOLIN-1 -- FICOLIN-2 -- FICOLIN-3 -- STRUCTURE -- FUNCTION -- Lectin and Binding Activities -- Binding of Ficolins to Microorganisms -- Lectin Pathway Activation. , Cross Talk and Collaboration of Ficolins With Noncomplement Proteins -- Roles in Homeostasis -- TISSUE DISTRIBUTION -- PROTEIN SEQUENCE -- PROTEIN MODULES -- Splicing Variants of Ficolins -- CHROMOSOMAL LOCATION -- CDNA SEQUENCE -- GENOMIC STRUCTURE -- Accession Numbers -- POLYMORPHIC VARIANTS -- FICOLIN-DEFICIENT MOUSE -- REFERENCES -- 6 - The Collectins -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- CRYSTAL STRUCTURE -- FUNCTION -- Sugar Specificity -- Ligand Specificity -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- II - Serine Proteases -- 7 - MASP-1 -- PHYSICOCHEMICAL PROPERTIES -- Immature Protein -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION16 -- HUMAN CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 8 - MASP-2 -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION14 -- HUMAN CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 9 - MASP-3 -- PHYSICOCHEMICAL PROPERTIES -- Immature Protein -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION18 -- HUMAN CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 10 - C1r -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- 3D Structure -- FUNCTION. , TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE20-23 -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE22 -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 11 - C1s -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- 3D STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE26-28 -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE26 -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 12 - Factor D -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- DEGRADATION PATHWAY -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- CDNA SEQUENCES -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- FURTHER READING -- 13 - C2 -- PHYSIOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- EXPRESSION AND REGULATION -- PROTEIN SEQUENCE12,13 -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 14 - Factor B -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- PROTEIN SEQUENCES -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 15 - Factor I -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- PROTEIN SEQUENCES -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- CDNA SEQUENCES AND GENOMIC STRUCTURE. , POLYMORPHIC VARIANTS, DEFICIENCY AND DISEASE-RELATED SINGLE NUCLEOTIDE POLYMORPHISMS -- FI KNOCKOUT MICE -- REFERENCES -- III - C3 Family -- 16 - C3 -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- DEGRADATION PATHWAY -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 17 - C4 -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- PROTEIN SEQUENCE31 -- PROTEIN MODULES -- CHROMOSOMAL LOCATION33 -- CDNA SEQUENCE31,34 -- cDNA Sequence-Continued -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- Naturally Occurring C4 Deficiency -- C4 KNOCKOUT MOUSE PHENOTYPES -- REFERENCES -- 18 - C5 -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- DEGRADATION PATHWAY -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE3 -- HUMAN PROTEIN SEQUENCE-CONTINUED -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE -- HUMAN CDNA SEQUENCE-CONTINUED -- HUMAN CDNA SEQUENCE-CONTINUED -- Genomic Structure26,27 -- ACCESSION NUMBERS -- DEFICIENCY -- African-American Families28 -- Western Cape, South African Families29 -- Saudi Family30 -- Spanish Families31,32 -- Italian Family31 -- Brazilian Family33 -- Turkish Family34 -- Norwegian Family35 -- Danish Family35 -- Dutch Family36 -- Morocco Families37 -- POLYMORPHIC VARIANTS38 -- MUTANT ANIMALS -- REFERENCES -- IV - Terminal Pathway Components -- 19 - C6 -- PHYSIOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE1,2 -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE1,2. , GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 20 - C7 -- PHYSIOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE1 -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE1 -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 21 - C8 -- PHYSIOCHEMICAL PROPERTIES -- STRUCTURE -- CRYSTAL STRUCTURES -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- C8α19 -- C8β20, 21 -- C8γ22 -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE -- C8α19 -- C8β20, 21 -- C8γ22 -- GENOMIC STRUCTURE -- C8α24 -- C8β25 -- C8γ26 -- Polymorphic Variants -- MUTANT ANIMALS -- REFERENCES -- 22 - C9 -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE -- HUMAN CDNA SEQUENCE-CONTINUED -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- V - Regulatory Proteins -- 23 - C1 Inhibitor -- PHYSICOCHEMICAL PROPERTIES -- Immature Protein -- Mature Protein -- STRUCTURE -- FUNCTIONS -- DEGRADATION PATHWAY -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- CDNA SEQUENCE -- GENOMIC STRUCTURE -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 24 - C4b-Binding Protein -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- PROTEIN SEQUENCES -- PROTEIN MODULES -- CHROMOSOMAL LOCATION AND GENOMIC STRUCTURE -- CDNA SEQUENCES -- DEFICIENCY -- POLYMORPHIC VARIANTS AND DISEASE-RELATED SINGLE NUCLEOTIDE POLYMORPHISMS. , C4BP KNOCKOUT AND TRANSGENIC MICE.

Sprache: Englisch

UID:

Umfang: 1 online resource (514 pages) : , illustrations (some color), tables

Ausgabe: Second edition.

ISBN: 0-12-810420-1 , 0-12-810421-X

Anmerkung: Front Cover -- The Complement FactsBook -- The Complement FactsBook -- Copyright -- Contents -- List of Contributors -- Preface -- 1 - Introduction -- AIMS AND SCOPE OF THE BOOK -- ORGANISATION OF THE DATA -- Other Names -- Physicochemical Properties -- Structure -- Function -- Degradation Pathway -- Tissue Distribution -- Regulation of Expression -- Human Protein Sequence -- Protein Modules -- Chromosomal Location -- cDNA Sequence -- Genomic Structure -- Accession Numbers -- Deficiency -- Polymorphic Variants -- Mutant Animals -- REFERENCE -- 2 - The Complement System -- HISTORICAL PERSPECTIVE -- MODULAR STRUCTURE OF THE COMPONENTS -- The Collectins -- Serine Proteases -- C3 Family -- Terminal Pathway -- Regulatory Proteins -- The Leucocyte Receptors -- PATHWAYS -- Classical Pathway -- Lectin Pathway -- Alternative Pathway -- Terminal Pathway -- REFERENCES -- I - Collectins -- 3 - C1q -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- DEGRADATION PATHWAY -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- FURTHER READING -- 4 - Mannose-Binding Lectin -- OTHER NAMES OF MANNOSE-BINDING LECTIN -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 5 - Ficolins -- OTHER NAMES FOR FICOLINS -- PHYSICOCHEMICAL PROPERTIES -- FICOLIN-1 -- FICOLIN-2 -- FICOLIN-3 -- STRUCTURE -- FUNCTION -- Lectin and Binding Activities -- Binding of Ficolins to Microorganisms -- Lectin Pathway Activation. , Cross Talk and Collaboration of Ficolins With Noncomplement Proteins -- Roles in Homeostasis -- TISSUE DISTRIBUTION -- PROTEIN SEQUENCE -- PROTEIN MODULES -- Splicing Variants of Ficolins -- CHROMOSOMAL LOCATION -- CDNA SEQUENCE -- GENOMIC STRUCTURE -- Accession Numbers -- POLYMORPHIC VARIANTS -- FICOLIN-DEFICIENT MOUSE -- REFERENCES -- 6 - The Collectins -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- CRYSTAL STRUCTURE -- FUNCTION -- Sugar Specificity -- Ligand Specificity -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- II - Serine Proteases -- 7 - MASP-1 -- PHYSICOCHEMICAL PROPERTIES -- Immature Protein -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION16 -- HUMAN CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 8 - MASP-2 -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION14 -- HUMAN CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 9 - MASP-3 -- PHYSICOCHEMICAL PROPERTIES -- Immature Protein -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION18 -- HUMAN CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 10 - C1r -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- 3D Structure -- FUNCTION. , TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE20-23 -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE22 -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 11 - C1s -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- 3D STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE26-28 -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE26 -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 12 - Factor D -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- DEGRADATION PATHWAY -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- CDNA SEQUENCES -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- FURTHER READING -- 13 - C2 -- PHYSIOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- EXPRESSION AND REGULATION -- PROTEIN SEQUENCE12,13 -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 14 - Factor B -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- PROTEIN SEQUENCES -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 15 - Factor I -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- PROTEIN SEQUENCES -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- CDNA SEQUENCES AND GENOMIC STRUCTURE. , POLYMORPHIC VARIANTS, DEFICIENCY AND DISEASE-RELATED SINGLE NUCLEOTIDE POLYMORPHISMS -- FI KNOCKOUT MICE -- REFERENCES -- III - C3 Family -- 16 - C3 -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- DEGRADATION PATHWAY -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 17 - C4 -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- PROTEIN SEQUENCE31 -- PROTEIN MODULES -- CHROMOSOMAL LOCATION33 -- CDNA SEQUENCE31,34 -- cDNA Sequence-Continued -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- Naturally Occurring C4 Deficiency -- C4 KNOCKOUT MOUSE PHENOTYPES -- REFERENCES -- 18 - C5 -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- DEGRADATION PATHWAY -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE3 -- HUMAN PROTEIN SEQUENCE-CONTINUED -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE -- HUMAN CDNA SEQUENCE-CONTINUED -- HUMAN CDNA SEQUENCE-CONTINUED -- Genomic Structure26,27 -- ACCESSION NUMBERS -- DEFICIENCY -- African-American Families28 -- Western Cape, South African Families29 -- Saudi Family30 -- Spanish Families31,32 -- Italian Family31 -- Brazilian Family33 -- Turkish Family34 -- Norwegian Family35 -- Danish Family35 -- Dutch Family36 -- Morocco Families37 -- POLYMORPHIC VARIANTS38 -- MUTANT ANIMALS -- REFERENCES -- IV - Terminal Pathway Components -- 19 - C6 -- PHYSIOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE1,2 -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE1,2. , GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 20 - C7 -- PHYSIOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE1 -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE1 -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 21 - C8 -- PHYSIOCHEMICAL PROPERTIES -- STRUCTURE -- CRYSTAL STRUCTURES -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- C8α19 -- C8β20, 21 -- C8γ22 -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE -- C8α19 -- C8β20, 21 -- C8γ22 -- GENOMIC STRUCTURE -- C8α24 -- C8β25 -- C8γ26 -- Polymorphic Variants -- MUTANT ANIMALS -- REFERENCES -- 22 - C9 -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- HUMAN CDNA SEQUENCE -- HUMAN CDNA SEQUENCE-CONTINUED -- GENOMIC STRUCTURE -- ACCESSION NUMBERS -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- V - Regulatory Proteins -- 23 - C1 Inhibitor -- PHYSICOCHEMICAL PROPERTIES -- Immature Protein -- Mature Protein -- STRUCTURE -- FUNCTIONS -- DEGRADATION PATHWAY -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- HUMAN PROTEIN SEQUENCE -- PROTEIN MODULES -- CHROMOSOMAL LOCATION -- CDNA SEQUENCE -- GENOMIC STRUCTURE -- DEFICIENCY -- POLYMORPHIC VARIANTS -- MUTANT ANIMALS -- REFERENCES -- 24 - C4b-Binding Protein -- OTHER NAMES -- PHYSICOCHEMICAL PROPERTIES -- STRUCTURE -- FUNCTION -- TISSUE DISTRIBUTION -- REGULATION OF EXPRESSION -- PROTEIN SEQUENCES -- PROTEIN MODULES -- CHROMOSOMAL LOCATION AND GENOMIC STRUCTURE -- CDNA SEQUENCES -- DEFICIENCY -- POLYMORPHIC VARIANTS AND DISEASE-RELATED SINGLE NUCLEOTIDE POLYMORPHISMS. , C4BP KNOCKOUT AND TRANSGENIC MICE.

Sprache: Englisch