UID:
almahu_9949983665202882
Format:
1 online resource (550 pages)
ISBN:
9780128201084
,
0128201088
,
9780128201077
,
012820107X
Series Statement:
Issn
Note:
Intro -- The Human Hypothalamus: Middle and Posterior Region -- Copyright -- Handbook of Clinical Neurology 3rd Series -- Foreword -- Preface -- The HCN volumes on the Human Hypothalamus -- The hypothalamus: Arbitrary borders -- References -- Contributors -- Contents -- Contents of related volumes -- Chapter 1: Introduction: The middle and posterior hypothalamus -- Section 6#: Supraoptic and Paraventricular Nucleus: More than a Neuroendocrine System -- Section 7: Zona Incerta -- Section 8: Ventromedial Nucleus and Dorsomedial Nucleus -- Section 9: Circumventricular Organs of the Hypothalamus -- Section 10: Lateral Tuberal Nucleus -- Section 11: Lateral Hypothalamic Area, Perifornical Area -- Section 12: Tuberomamillary Complex -- Section 13: Subthalamic Nucleus -- Section 14: Corpora Mamillaria, Fornix, and Mamillothalamic Tract -- References -- Section 6: Supraoptic and paraventricular nucleus more than a neuroendocrine system -- Chapter 2: Vasopressin and oxytocin beyond the pituitary in the human brain -- Accessory Magnocellular Neuroendocrine System of the Hypothalamus -- Vasopressin- and Oxytocin-Containing Neurons and Fibers in the Forebrain -- Vasopressin and Oxytocin Are Involved in Motivated Social Behavior -- Localization of the Neurons Involved in Behavioral and Physiological Functions and Targeted by Vasopressinergic and Oxytociner -- Forebrain -- Brainstem and spinal cord -- Vasopressin in the Suprachiasmatic Nucleus -- Vasotocin, Vasopressin, and Oxytocin in the Mammalian Pineal Gland -- Conclusions -- References -- Chapter 3: Central and peripheral release of oxytocin: Relevance of neuroendocrine and neurotransmitter actions for physi ... -- Introduction -- Organization of the Hypothalamic-Neurohypophyseal (HHNS) System -- Parvocellular Oxytocin Neurons of the Hypothalamus: Master Cells Arranging the HHNS Activity?.
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Heterogeneity of Oxytocin Neurons -- Synaptic vs Nonsynaptic Oxytocin Release -- Intracellular Oxytocin Receptor Signaling -- Oxytocin System in Monkeys and Human -- Oxytocin in Human Health -- Perspectives -- Acknowledgments -- References -- Chapter 4: Organization of the neuroendocrine and autonomic hypothalamic paraventricular nucleus -- Introduction1 -- Hypothalamic Integration of Time of Day -- Control of the Daily Rhythm in HPA axis Activity -- Control of the Daily Rhythm in HPT Axis Activity -- Control of the Daily Rhythm in Prolactin Release -- Control of the Daily Rhythm in Pineal Melatonin Release -- Control of the Daily Rhythm in Plasma Glucose Concentrations -- Control of the Daily Rhythm in Feeding-Induced Insulin Responses -- Multiple Subpopulations of Preautonomic Neurons -- Future Perspective -- References -- Chapter 5: Sex differences of oxytocin and vasopressin in social behaviors -- Introduction -- Models and Interventions -- Sexually Dimorphic Influences of OT on Social Cognition -- Partner preference and sexual orientation -- Memory modulation -- Emotion regulation -- Trust-related behaviors -- Sexually Dimorphic Influences of VP on Social Cognition -- Effects of OT and VP on Social Cognition of Women During Pregnancy, Birth, and Lactation -- OT in peripartum period -- VP in peripartum period -- Discussion -- References -- Chapter 6: Oxytocin, eating behavior, and metabolism in humans -- Oxytocin Neurophysiology-Relation to Energy Homeostasis -- Endogenous Oxytocin Levels, Eating Behavior, and Metabolic Status in Humans -- Measurement of oxytocin -- Endogenous oxytocin levels in healthy individuals and patients with disrupted oxytocin pathways -- Oxytocin levels in obesity and metabolic disorders -- The Effects of Oxytocin Administration on Caloric Intake and Metabolism.
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The Effects of Oxytocin Administration in Individuals with Obesity and Suspected Insult to Oxytocin Pathways -- Therapeutic Opportunities and Challenges -- Competing interests statement -- References -- Chapter 7: The supraoptic and paraventricular nuclei in healthy aging and neurodegeneration -- The Supraoptic and Paraventricular Nuclei in Healthy Aging -- Morphological changes in aging -- Sex differences in aging -- Vasopressin -- Oxytocin -- Corticotropin-releasing hormone -- Thyrotropin-releasing hormone -- Hormone changes in aging -- Vasopressin -- Oxytocin -- Corticotropin-releasing hormone -- Thyrotropin-releasing hormone -- Circuit changes in aging -- Hypothalamic-pituitary-adrenal axis -- Hypothalamic-pituitary-thyroid axis -- The Supraoptic and Paraventricular Nuclei in Neurodegeneration -- Alzheimer's disease -- Abnormal inclusions and aggregates -- Neuronal loss and other pathological changes -- Hormonal changes -- Circuit alterations and disruption -- Frontotemporal dementia -- Abnormal inclusions and aggregates -- Neuronal loss and other pathological changes -- Hormonal changes -- Circuit alterations and disruption -- Amyotrophic lateral sclerosis -- Abnormal inclusions and aggregates -- Neuronal loss and pathological changes -- Hormonal changes -- Circuit alterations and disruption -- Progressive supranuclear palsy -- Abnormal inclusions and aggregates -- Neuronal loss and pathological changes -- Hormonal changes -- Circuit alterations and disruption -- Parkinson's disease -- Abnormal inclusions and aggregates -- Neuronal loss and pathological changes -- Hormonal changes -- Circuit alterations and disruption -- Dementia with Lewy bodies -- Abnormal inclusions and aggregates -- Neuronal loss and pathological changes -- Hormonal changes -- Circuit alterations and disruption -- Multiple system atrophy -- Abnormal inclusions and aggregates.
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Neuronal loss and pathological changes -- Hormonal changes -- Circuit alterations and disruption -- Huntington's disease -- Abnormal inclusions and aggregates -- Neuronal loss and pathological changes -- Hormonal changes -- Circuit alterations and disruption -- Conclusion -- References -- Chapter 8: Perinatal stress and epigenetics -- Introduction: DNA Methylation and Cellular Identity -- DNA Methylation and Gene Function -- Epigenetic Programming of the HPA Axis by Maternal Behavior and Its Reversal by Epigenetic Regulators -- Early Life Stress-Mediated Epigenetic Reprogramming of the HPA axis: Epigenetic Changes in the Hypothalamus -- Early Life Stress/Adversity Causes Broad Epigenetic Changes Across the Genome Which Are Evolutionary Conserved -- The Effect of Early Life Stress/Adversity-related Broad Epigenetic Changes in Peripheral Tissues Outside the -- Socioeconomic Positioning and Epigenetic Programming -- Early Life Stress and PTSD -- Cross-Generational Effects of Trauma -- Early Life Stress Methylation and Metabolic Control -- Epigenetic Processes Mediating Effects of Stress During Adulthood -- DNA Methylation Programming of the HPA axis in Response to ELS: A Genomic Mechanism of Adaptation -- Dynamic Epigenetic Programming in Response to Early Life Experience: Setting up Future Gene Expression Trajectories -- What Are the Mechanisms that Mediate Between Experience and DNA Methylation Alterations in the HPA axis and Somatic Tissues an -- Summary and Perspective -- Acknowledgment -- References -- Chapter 9: The hypothalamus in anxiety disorders -- Introduction -- Oxytocin -- Corticotropin-Releasing Hormone -- Thyrotropin-Releasing Hormone -- Conclusion -- Acknowledgment -- References -- Chapter 10: Congenital isolated central hypothyroidism: Novel mutations and their functional implications -- Introduction.
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The hypothalamus-pituitary-thyroid axis -- Cellular thyroid hormone metabolism and action -- Hypothyroidism -- Congenital hypothyroidism -- Genetics of Congenital Isolated Central Hypothyroidism -- TSH β-subunit gene -- TRH receptor gene -- IGSF1 gene -- TBL1X gene -- IRS4 gene -- Central Hypothyroidism and Neonatal Screening -- Congenital Central Hypothyroidism-Clinical Aspects -- Diagnosis -- Management and treatment -- Concluding Remarks -- References -- Section 7: Zona incerta -- Chapter 11: The zona incerta system: Involvement in attention and movement -- Introduction -- Organization of the Zona Incerta -- Connections of the Zona Incerta -- Connections with the cerebral cortex -- Connections with the superior colliculus (SC) -- Connections with the thalamus -- Other connections of the zona incerta -- Related to the basal ganglia -- Related to motor and cerebellum -- Related to somatosensory afferents -- Related to the hypothalamus and reticular formation -- Overall Functional Networks of the Zona Incerta -- The zona incerta within the vibrissal system -- The zona incerta and the switching of behaviors -- The case of the rostromedial zona incerta -- Conclusions -- References -- Section 8: Ventromedial nucleus and dorsomedial nucleus -- Chapter 12: The role of the dorsomedial and ventromedial hypothalamus in regulating behaviorally coupled and resting auto ... -- DMH and VMH Locations and Anatomical Projection Patterns -- DMH and Cardiovascular Control -- Acute stressors -- Thermoregulation -- VMH and Cardiovascular Control -- Resting sympathetic drive -- Conclusions -- References -- Section 9: Circumventricular organs of the hypothalamus -- Chapter 13: The subfornical organ and organum vasculosum of the lamina terminalis: Critical roles in cardiovascular regul ... -- Introduction -- General Anatomy.
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Systemic or Local Administration Studies Demonstrating a Synergistic Role in Fluid Balance and Cardiovascular Regulation.
Language:
English
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