Kooperativer Bibliotheksverbund

UID:

Format: 1 online resource (634 pages)

ISBN: 0-443-13313-1

Content: Medicines for Cancer: Mechanism of Action and Clinical Pharmacology of Chemo, Hormonal, Targeted, and Immunotherapies covers most known anti-cancer therapeutics. Cancer is the second leading cause of death worldwide, with its various forms resulting in nearly one out of every six mortalities each year. This book describes all US FDA-approved drugs (up to 2021), such as small molecules, peptides, monoclonal antibodies, whole antibodies, gene therapy, antibody-drug conjugates, cell therapy, and immunotherapies, along with information on their generic and brand names, medical uses, details dosage, mechanisms of actions, pharmacokinetics and side effects. Chemical structures of small molecules, small peptides, antibody-drug conjugates are also provided. This book is ideal for medicinal chemists, oncologists, and pharmacologists, but it will also be indispensable for professional researchers, whether they are working in the clinic or the pharmaceutical industry.

Note: Front Cover -- Medicines for Cancer -- Medicines for Cancer: MECHANISM OF ACTION AND CLINICAL PHARMACOLOGY OF CHEMO, HORMONAL, TARGETED, AND IMMUNOTHERAPIES -- Copyright -- Medical advice disclaimer -- Contents -- About the author -- Preface -- Common abbreviations and acronyms -- 1 - Drug nomenclature -- 1.1 Generic formula -- References -- 2 - Chemotherapy -- 2.1 Alkylating antineoplastic agents -- 2.2 Nitrosoureas -- 2.3 Antimetabolites -- 2.4 Antitumor antibiotics -- 2.4.1 Anthracyclines -- 2.4.2 Nonanthracyclines -- 2.5 Topoisomerase inhibitors -- 2.6 Mitotic inhibitors (antimicrotubule agents) -- 2.7 Corticosteroids -- 2.8 Other chemotherapy drugs -- 2.9 US FDA-approved current chemotherapy agents -- 2.10 Albumin-bound paclitaxel -- 2.10.1 Indications (medical uses) -- 2.10.2 Metastatic breast cancer -- 2.10.3 Dosage and administration -- 2.10.4 Mechanism of action -- 2.10.5 Pharmacokinetics -- 2.10.6 Side effects -- 2.11 Amifostine -- 2.11.1 Indications (medical uses) -- 2.11.2 Dosage and administration -- 2.11.3 Mechanism of action -- 2.11.4 Pharmacokinetics -- 2.11.5 Side effects -- 2.12 Arsenic trioxide -- 2.12.1 Indications (medical uses) -- 2.12.2 Dosage and administration -- 2.12.3 Mechanism of action -- 2.12.4 Pharmacokinetics -- 2.12.5 Side effects -- 2.13 Asparaginase Erwinia chrysanthemi -- 2.13.1 Indications (medical uses) -- 2.13.2 Dosage and administration -- 2.13.3 Mechanism of action -- 2.13.4 Pharmacokinetics -- 2.13.5 Side effects -- 2.14 Azacitidine -- 2.14.1 Indications (medical uses) -- 2.14.2 Dosage and administration -- 2.14.3 Mechanism of action -- 2.14.4 Pharmacokinetics -- 2.14.5 Side effects -- 2.15 Bendamustine -- 2.15.1 Indications (medical uses) -- 2.15.2 Dosage and administration -- 2.15.3 Mechanism of action -- 2.15.4 Pharmacokinetics -- 2.15.5 Side effects -- 2.16 Bleomycin. , 2.16.1 Indications (medical uses) -- 2.16.2 Dosage and administration -- 2.16.3 Mechanism of action -- 2.16.4 Pharmacokinetics -- 2.16.5 Metabolism -- 2.16.6 Side effects -- 2.17 Busulfan -- 2.17.1 Indications (medical uses) -- 2.17.2 Dosage and administration -- 2.17.3 Mechanism of action -- 2.17.4 Pharmacokinetics -- 2.17.5 Side effects -- 2.18 Cabazitaxel -- 2.18.1 Indications (medical uses) -- 2.18.2 Dosage and administration -- 2.18.3 Mechanism of action -- 2.18.4 Pharmacokinetics -- 2.18.5 Side effects -- 2.19 Calaspargase pegol-mknl -- 2.19.1 Indications (medical uses) -- 2.19.2 Dosage and administration -- 2.19.3 Mechanism of action -- 2.19.4 Pharmacokinetics -- 2.19.5 Side effects -- 2.20 Capecitabine -- 2.20.1 Indications (medical uses) -- 2.20.2 Dosage and administration -- 2.20.3 Mechanism of action -- 2.20.4 Pharmacokinetics -- 2.20.5 Side effects -- 2.21 Carboplatin -- 2.21.1 Indications (medical uses) -- 2.21.2 Dosage and administration -- 2.21.3 Mechanism of action -- 2.21.4 Pharmacokinetics -- 2.21.5 Side effects -- 2.22 Carmustine -- 2.22.1 Indications (medical uses) -- 2.22.2 Dosage and administration -- 2.22.3 Mechanism of action -- 2.22.4 Pharmacokinetics -- 2.22.5 Side effects -- 2.23 Chlorambucil -- 2.23.1 Indications (medical uses) -- 2.23.2 Dosage and administration -- 2.23.3 Mechanism of action -- 2.23.4 Pharmacokinetics -- 2.23.5 Side effects -- 2.24 Cisplatin -- 2.24.1 Indications (medical uses) -- 2.24.2 Dosage and administration -- 2.24.3 Mechanism of action -- 2.24.4 Pharmacokinetics -- 2.24.5 Side effects -- 2.25 Cladribine -- 2.25.1 Indications (medical uses) -- 2.25.2 Dosage and administration -- 2.25.3 Mechanism of action -- 2.25.4 Pharmacokinetics -- 2.25.5 Side effects -- 2.26 Clofarabine -- 2.26.1 Indications (medical uses) -- 2.26.2 Dosage and administration -- 2.26.3 Mechanism of action. , 2.26.4 Pharmacokinetics -- 2.26.5 Side effects -- 2.27 Cyclophosphamide -- 2.27.1 Indications (medical uses) -- 2.27.2 Dosage and administration -- 2.27.3 Mechanism of action -- 2.27.4 Pharmacokinetics -- 2.27.5 Side effects -- 2.28 Cytarabine -- 2.28.1 Indications (medical uses) -- 2.28.2 Dosage and administration -- 2.28.3 Mechanism of action -- 2.28.4 Pharmacokinetics -- 2.28.5 Side effects -- 2.29 Dacarbazine -- 2.29.1 Indications (medical uses) -- 2.29.2 Dosage and administration -- 2.29.3 Mechanism of action -- 2.29.4 Pharmacokinetics -- 2.29.5 Side effects -- 2.30 Dactinomycin -- 2.30.1 Indications (medical uses) -- 2.30.2 Dosage and administration -- 2.30.3 Mechanism of action -- 2.30.4 Pharmacokinetics -- 2.30.5 Side effects -- 2.31 Daunorubicin -- 2.31.1 Indications (medical uses) -- 2.31.2 Dosage and administration -- 2.31.3 Mechanism of action -- 2.31.4 Pharmacokinetics -- 2.31.5 Side effects -- 2.32 Decitabine -- 2.32.1 Indications (medical uses) -- 2.32.2 Dosage and administration -- 2.32.3 Mechanism of action -- 2.32.4 Pharmacokinetics -- 2.32.5 Side effects -- 2.33 Dexamethasone -- 2.33.1 Dosage and administration -- 2.33.2 Mechanism of action -- 2.33.3 Pharmacokinetics -- 2.33.4 Side effects -- 2.34 Docetaxel -- 2.34.1 Indications (medical uses) -- 2.34.2 Dosage and administration -- 2.34.3 Mechanism of action -- 2.34.4 Pharmacokinetics -- 2.34.5 Side effects -- 2.35 Doxorubicin -- 2.35.1 Indications (medical uses) -- 2.35.2 Dosage and administration -- 2.35.3 Mechanism of action -- 2.35.4 Pharmacokinetics -- 2.35.5 Side effects -- 2.36 Doxorubicin liposome -- 2.36.1 Indications (medical uses) -- 2.36.2 Dosage and administration -- 2.36.3 Mechanism of action -- 2.36.4 Pharmacokinetics -- 2.36.5 Side effects -- 2.37 Epirubicin -- 2.37.1 Indications (medical uses) -- 2.37.2 Dosage and administration -- 2.37.3 Mechanism of action. , 2.37.4 Pharmacokinetics -- 2.37.5 Side effects -- 2.38 Eribulin mesylate -- 2.38.1 Indications (medical uses) -- 2.38.2 Dosage and administration -- 2.38.3 Mechanism of action -- 2.38.4 Pharmacokinetics -- 2.38.5 Side effects -- 2.39 Etoposide -- 2.39.1 Indications (medical uses) -- 2.39.2 Dosage and administration -- 2.39.3 Mechanism of action -- 2.39.4 Pharmacokinetics -- 2.39.5 Side effects -- 2.40 Fludarabine -- 2.40.1 Indications (medical uses) -- 2.40.2 Dosage and administration -- 2.40.3 Mechanism of action -- 2.40.4 Pharmacokinetics -- 2.40.5 Side effects -- 2.41 5-Fluorouracil -- 2.41.1 Indications (medical uses) -- 2.41.2 Dosage and administration -- 2.41.3 Mechanism of action -- 2.41.4 Pharmacokinetics -- 2.41.5 Side effects -- 2.42 Gemcitabine -- 2.42.1 Indications (medical uses) -- 2.42.2 Dosage and administration -- 2.42.3 Mechanism of action -- 2.42.4 Pharmacokinetics -- 2.42.5 Side effects -- 2.43 Hydroxyurea -- 2.43.1 Indications (medical uses) -- 2.43.2 Dosage and administration -- 2.43.3 Mechanism of action -- 2.43.4 Pharmacokinetics -- 2.43.5 Side effects -- 2.44 Idarubicin -- 2.44.1 Indications (medical uses) -- 2.44.2 Dosage and administration -- 2.44.3 Mechanism of action -- 2.44.4 Pharmacokinetics -- 2.44.5 Side effects -- 2.45 Ifosfamide -- 2.45.1 Indications (medical uses) -- 2.45.2 Dosage and administration -- 2.45.3 Mechanism of action -- 2.45.4 Pharmacokinetics -- 2.45.5 Side effects -- 2.46 Irinotecan -- 2.46.1 Indications (medical uses) -- 2.46.2 Dosage and administration -- 2.46.3 Mechanism of action -- 2.46.4 Pharmacokinetics -- 2.46.5 Side effects -- 2.47 Ixabepilone -- 2.47.1 Indications (medical uses) -- 2.47.2 Dosage and administration -- 2.47.3 Mechanism of action -- 2.47.4 Pharmacokinetics -- 2.47.5 Side effects -- 2.48 Lomustine -- 2.48.1 Indications (medical uses) -- 2.48.2 Dosage and administration. , 2.48.3 Mechanism of action -- 2.48.4 Pharmacokinetics -- 2.48.5 Side effects -- 2.49 Lurbinectedin -- 2.49.1 Indications (medical uses) -- 2.49.2 Dosage and administration -- 2.49.3 Mechanism of action -- 2.49.4 Pharmacokinetics -- 2.49.5 Side effects -- 2.50 Lutetium Lu 177-dotatate -- 2.50.1 Indications (medical uses) -- 2.50.2 Dosage and administration -- 2.50.3 Mechanism of action -- 2.50.4 Pharmacokinetics -- 2.50.5 Side effects -- 2.51 Mechlorethamine -- 2.51.1 Indications (medical uses) -- 2.51.2 Dosage and administration -- 2.51.3 Mechanism of action -- 2.51.4 Pharmacokinetics -- 2.51.5 Side effects -- 2.52 Melphalan -- 2.52.1 Indications (medical uses) -- 2.52.2 Dosage and administration -- 2.52.3 Mechanism of action -- 2.52.4 Pharmacokinetics -- 2.52.5 Side effects -- 2.53 Mercaptopurine -- 2.53.1 Indications (medical uses) -- 2.53.2 Dosage and administration -- 2.53.3 Mechanism of action -- 2.53.4 Pharmacokinetics -- 2.53.5 Side effects -- 2.54 Methotrexate -- 2.54.1 Indications (medical uses) -- 2.54.2 Dosage and administration -- 2.54.3 Mechanism of action -- 2.54.4 Pharmacokinetics -- 2.54.5 Side effects -- 2.55 Mitomycin-C -- 2.55.1 Indications (medical uses) -- 2.55.2 Dosage and administration -- 2.55.3 Mechanism of action -- 2.55.4 Pharmacokinetics -- 2.55.5 Side effects -- 2.56 Mitoxantrone -- 2.56.1 Indications (medical uses) -- 2.56.2 Dosage and administration -- 2.56.3 Mechanism of action -- 2.56.4 Pharmacokinetics -- 2.56.5 Side effects -- 2.57 Nelarabine -- 2.57.1 Indications (medical uses) -- 2.57.2 Dosage and administration -- 2.57.3 Mechanism of action -- 2.57.4 Pharmacokinetics -- 2.57.5 Side effects -- 2.58 Oxaliplatin -- 2.58.1 Indications (medical uses) -- 2.58.2 Dosage and administration -- 2.58.3 Mechanism of action -- 2.58.4 Pharmacokinetics -- 2.58.5 Side effects -- 2.59 Paclitaxel -- 2.59.1 Indications (medical uses).

Additional Edition: Print version: De, Surya K. Medicines for Cancer San Diego : Elsevier,c2023 ISBN 9780443133121

Additional Edition: ISBN 9780443133138

Additional Edition: ISBN 0443133123

Language: English