UID:
almahu_9949983507502882
Umfang:
1 online resource (286 pages)
ISBN:
9780443185366
,
0443185360
Inhalt:
"Advances in Extraction and Applications of Bioactive Phytochemicals presents comprehensive and systematic coverage of extraction techniques for bioactive phytochemical compounds and their delivery and therapeutic effectiveness. Sections focus on the pharmaceutical industry’s perspective, aiming at compiling recent advances of natural products in the field of drug delivery, including a brief overview of plant-based bioactive molecules, utilization of different plant elements for the extraction of phytochemicals, a compilation of conventional extraction approaches, advanced extraction methods, including Supercritical carbon-dioxide extraction, computational methods to improve production, drug delivery aspects of bioactive phytochemicals, their therapeutic effectiveness, and more."--
Anmerkung:
Front Cover -- Advances in Extraction and Applications of Bioactive Phytochemicals -- Advances in Extraction and Applications of Bioactive Phytochemicals -- Copyright -- Contents -- Author biography -- Preface -- Acknowledgment -- 1 - Pharmaceutical prospects of plant-based bioactive molecules -- 1.1 Introduction -- 1.2 Overview and structural compositions of naturally occurring bioactive phytochemical compounds -- 1.2.1 Polyphenols -- 1.2.1.1 Properties of polyphenols -- 1.2.2 Alkaloids -- 1.2.2.1 Heterocyclic alkaloids -- 1.2.2.2 Nonheterocyclic alkaloids -- 1.2.2.3 Properties of alkaloids -- 1.2.3 Steroids -- 1.2.4 Terpenes -- 1.2.5 Pigments -- 1.2.6 Others -- 1.3 Analytical approaches for determining bioavailability and bioaccessibility of bioactive compounds -- 1.4 Commercialization of naturally occurring bioactive compounds -- 1.5 Conclusions and future perspectives -- References -- 2 - Utilization of various parts of the plant for the extraction of phytochemicals and high-throughput screening te ... -- 2.1 Introduction -- 2.2 Different parts of plants used to produce the pharmaceutically active compound -- 2.2.1 Extracted from leaves -- 2.2.2 Extracted from flower and seed -- 2.2.3 Extracted from stem bark -- 2.2.4 Extracted from the root -- 2.2.5 Other parts of the plant -- 2.3 High-throughput screening techniques for bioactive phytochemicals -- 2.3.1 High-throughput screening platforms -- 2.3.2 Assay development and optimization -- 2.3.3 Primary and secondary screening -- 2.4 Summary -- References -- 3 - Conventional approaches for the extraction of bioactive compounds for pharmaceutical applications -- 3.1 Introduction -- 3.2 Conventional approaches for the extraction of bioactive compounds -- 3.2.1 Soxhlet extraction -- 3.2.1.1 High-pressure Soxhlet extraction -- 3.2.1.2 Ultrasound-assisted Soxhlet extraction.
,
3.2.1.3 Microwave-assisted Soxhlet extraction -- 3.2.2 Maceration -- 3.2.2.1 Modified maceration process -- 3.2.3 Infusion -- 3.2.4 Decoction -- 3.2.5 Percolation -- 3.2.6 Hydrodistillation -- 3.2.6.1 Water distillation -- 3.2.6.2 Water and steam distillation -- 3.2.6.3 Direct steam distillation -- 3.3 Limitations associated with the conventional techniques -- 3.4 Summary -- References -- 4 - Advancement in bioactive compound extraction from natural products for pharmaceutical applications -- 4.1 Introduction -- 4.2 Different extraction approaches -- 4.2.1 Microwave-assisted extraction -- 4.2.1.1 Important parameters -- 4.2.2 Ultrasound-assisted extraction -- 4.2.2.1 Important parameters -- 4.2.3 Pressurized liquid extraction -- 4.2.4 Supercritical carbon dioxide extraction -- 4.2.4.1 Important factors -- 4.2.5 Subcritical water extraction -- 4.2.5.1 Important parameters -- 4.2.6 Enzyme-assisted extraction -- 4.2.6.1 Important parameters -- 4.2.7 Infrared-assisted extraction -- 4.2.7.1 Important parameters -- 4.2.8 Flash extraction -- 4.2.9 Membrane-assisted extraction process -- 4.3 Future perspectives -- 4.4 Summary -- References -- 5 - Neoteric solvents for extraction of bioactive phytochemicals -- 5.1 Introduction -- 5.2 Classification of different synthetic solvents -- 5.2.1 Supercritical fluids -- 5.2.2 Fluorous solvents -- 5.2.3 Ionic liquids -- 5.2.3.1 Preparation of ionic liquid -- 5.2.4 Eutectic solvents -- 5.2.4.1 Deep eutectic solvent preparation -- 5.3 The emergence of solvent-free reactions in pharmaceutical industries -- 5.4 Summary -- References -- 6 - Application and effectiveness of computational methods in improving the production of bioactive phytochemicals -- 6.1 Introduction -- 6.2 Insight into the progress of different computational tools -- 6.2.1 Artificial intelligence.
,
6.2.2 Artificial intelligence in improving the production of secondary metabolites from plants -- 6.2.3 Artificial intelligence in plant tissue culture -- 6.2.4 Artificial intelligence in drug design and discovery -- 6.3 Insight into the advancement of molecular docking -- 6.3.1 Molecular docking in drug design -- 6.3.2 Application of molecular docking in the treatment of various diseases -- 6.4 Insight on molecular dynamics simulation for diseases and drug design -- 6.4.1 Adaptation of MD simulation for various diseases -- 6.4.2 Adaptation of MD simulation for drug designing -- 6.5 Summary -- References -- 7 - Advances in encapsulation strategies for bioactive phytochemicals -- 7.1 Introduction -- 7.2 Different encapsulation processes for bioactive compounds -- 7.2.1 Spray drying -- 7.2.2 Freeze-drying -- 7.2.3 Electrospraying -- 7.2.4 Electrospinning -- 7.2.5 Extrusion -- 7.2.5.1 Hot-melt extrusion -- 7.2.5.2 Melt injection extrusion process -- 7.2.5.3 Centrifugal extrusion (co-extrusion) -- 7.2.5.4 Electrostatic extrusion -- 7.2.6 Layer-by-layer disposition -- 7.3 Future perspectives -- 7.4 Summary -- References -- 8 - Applications of herb-derived bioactive phytochemicals -- 8.1 Introduction -- 8.2 Treatment of orthopedic diseases using herbal extracts -- 8.2.1 Icariin -- 8.2.2 Tetrandrine -- 8.2.3 Ursolic acid -- 8.3 Influence of herbal plants as immunity boosters in the treatment of COVID-19 and other diseases -- 8.3.1 Azadirachta indica -- 8.3.2 Phyllanthus emblica -- 8.3.3 Picrorhiza kurroa -- 8.3.4 Ocimum tenuiflorum -- 8.3.5 Withania somnifera -- 8.3.6 Piper nigrum -- 8.3.7 Zingiber officinale -- 8.3.8 Curcuma longa -- 8.4 Effect of herbal nanoformulation in the applications of tropical delivery -- 8.5 Summary -- References -- 9 - Pharmacologic and therapeutic aspects of various medicinal plants -- 9.1 Introduction.
,
9.2 Medicinal effect of Nigella sativa in different fields -- 9.2.1 Treatment for asthma -- 9.2.2 Role in diabetes control -- 9.2.3 Efficacy against different types of cancer -- 9.2.4 Common effects -- 9.3 Selective plants in the treatment of different diseases -- 9.3.1 Abelmoschus manihot -- 9.3.2 Abutilon indicum -- 9.3.3 Thespesia populnea -- 9.3.4 Solanum surattense -- 9.3.5 Mucuna pruriens -- 9.3.6 Senna auriculata -- 9.4 Medicinal efficacy of phytochemicals -- 9.4.1 Quercetin -- 9.4.2 Ferulic acid -- 9.4.3 Curcumin -- 9.4.4 Myricetin -- 9.5 Summary -- References -- 10 - Applications of plant-derived metal nanoparticles in pharmaceuticals -- 10.1 Introduction -- 10.2 Biosynthesis of metallic nanoparticles for pharmaceutical application -- 10.2.1 Silver nanoparticles -- 10.2.2 Gold nanoparticles -- 10.2.3 Copper nanoparticles -- 10.2.4 Other metallic nanoparticles -- 10.3 Factors influencing the production of metallic nanoparticles from plant extract -- 10.3.1 pH -- 10.3.2 Temperature -- 10.3.3 Reaction time -- 10.3.4 Concentration of plant extract -- 10.4 Application of metallic nanoparticles in pharmaceuticals -- 10.4.1 Antibacterial -- 10.4.2 Antiviral -- 10.4.3 Anticancer -- 10.4.4 Antioxidant -- 10.4.5 Other applications -- 10.5 Limitations and future perspectives -- 10.6 Summary -- References -- 11 - Patents on naturally derived pharmaceuticals -- 11.1 Introduction -- 11.2 Patents on naturally derived pharmaceuticals -- 11.2.1 Extraction of pharmaceutically active components from plant materials -- 11.2.2 Pharmaceutical and therapeutic compositions derived from Garcinia mangostana L plant -- 11.2.3 Hot-melt extruded compositions containing plant-derived phenolic materials and processes for the preparation thereof -- 11.2.4 Process for producing an antioxidant extract from the bearberry plant.
,
11.2.5 Use of bamboo leaf flavone in preparing cosmetics and food additives -- 11.2.6 Production of catechin from natural sources using membrane-based technology -- 11.2.7 Ginger extract and its preparing method and application -- 11.2.8 Method for producing vanillin and syringaldehyde by catalytic oxidation of alkali lignin of sugarcane residue -- 11.2.9 Processes for extracting carotenoids and for preparing feed materials -- 11.2.10 Aromatic carbon-coated iron-aluminum nanocomposite and its green synthetic process -- 11.2.11 Compositions of catechin flavonoids mixture -- 11.3 Summary -- References -- Index -- A -- B -- C -- D -- E -- F -- G -- H -- I -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- U -- W -- Z -- Back Cover.
Weitere Ausg.:
ISBN 9780443185359
Weitere Ausg.:
ISBN 0443185352
Sprache:
Englisch
Bookmarklink
