Kooperativer Bibliotheksverbund

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Umfang: 1 online resource (543 pages)

Ausgabe: 1st ed.

ISBN: 9780443237416 , 0443237417 , 9780443237409 , 0443237409

Serie: Micro and Nano Technologies Series

Anmerkung: Front Cover -- Nanotechnology-Based Sensing Platforms for Illicit Drugs -- Nanotechnology-Based Sensing Platforms for Illicit Drugs: Micro & -- Nano Technologies Series -- Copyright -- Contents -- Contributors -- 1 - General introduction to nanotechnology-based sensors -- Introduction -- Classification of nanosensors -- Surface modifications and nanosensors functionalization -- Nanosensors and their applications -- Optical nanosensors -- Fluorescent nanosenors -- Mechanical nanosensors -- Magnetic nanosensors -- Conclusions -- References -- 2 - Classical materials for sensors -- Introduction -- Applications of nanotechnology in detection of drugs -- Nanosensors and their working principle -- Colorimetric -- Surface-enhanced Raman spectroscopy -- Electrochemiluminescence -- Electrochemical -- Materials used as drug detection sensors -- Carbon-based material for drug detection -- Aptamers -- Metal nanoparticles -- Polymer materials -- Role of artificial intelligence in drug sensing -- Machine learning -- Deep learning -- Generative AI -- Conclusion -- References -- 3 - Chemical interactive behaviors of drugs -- Introduction -- Drug-receptor interactions -- Pharmacokinetics and drug interactive behavior -- Chemical interactions -- Polymer-drug interactions -- Quantum dots-drug interactions -- Conclusions -- AI disclosure -- References -- 4 - Drug detection methods -- Introduction -- Prevalent varieties of substances used for drug-facilitated sexual assault -- Alcohol -- Cannabis -- Cocaine -- Heroin -- MDMA (Ecstasy) -- Methamphetamine -- Rohypnol (flunitrazepam) -- Fentanyl -- Conventional techniques for detecting illicit drugs -- Detection windows -- Ultraviolet spectroscopy -- Thin-layer chromatography -- Immunoassay -- Mass spectrometry (MS) -- Summary -- References -- 5 - Design and fabrication strategies for drugs and biological sensors. , Introduction -- Overview on biosensors and nanosensors for drug detection -- Basic design and skeletal components of a sensor device -- Ideal materials and considerations for sensor fabrication -- Nanomaterials for enhanced sensitivity -- Biocompatible materials for in vivo applications -- Integration of molecularly imprinted polymers -- Considerations for wearable sensor design -- Materials for implantable sensors -- Smart materials for real-time monitoring -- Quantum materials and the way ahead -- Types of sensors and fabrication process -- Optical sensors -- Electrochemical sensors -- Piezoelectric sensors -- Challenges associated with the designing and fabrication of sensors -- Future perspectives for improvement in sensing technologies -- Conclusions -- References -- 6 - Characterization of various sensors -- Introduction -- Essential sensors for everyday activities -- Optical characterization methods -- Electrical characterization methods -- Thermal characterization methods -- Mechanical characterization methods -- Potential for future development and expansion -- Conclusions -- References -- 7 - Electrochemical detection of illicit drugs -- Introduction -- Electrochemical behavior of illicit drugs -- Synthesis and properties of nanomaterials-based composite for electrochemical sensors -- Nanoparticles-based composite -- Carbonaceous nanomaterials-based composite -- Nanofilms-based composite -- Application of nanomaterials composites-based electrochemical sensors for detection of illicit drugs -- Carbonaceous nanostructures-based sensor -- Metal/metal oxide nanomaterials-based sensors -- Polymer composites-based sensor -- Summary -- References -- 8 - Colorimetric sensors for illicit drug detection -- Introduction -- Illicit drugs-What are they? -- A brief explanation on chemical sensors. , Nanomaterials-based colorimetric detection of illicit drugs -- Colorimetric detection design based on lateral flow assay system -- Colorimetric detection design based on smartphone/mobile phones attached RGB system -- Colorimetric detection design based on microfluidic system -- Colorimetric detection design based on solution system -- Colorimetric detection design based on solid supports system -- Colorimetric detection design based on enzyme mimetic (peroxidase) system -- Common recognition materials applied in colorimetric detection fabrication -- Aptamers as biological recognition material -- Antibodies as biological recognition material -- Enzymes as biological recognition material -- Other biological recognition materials -- Colorimetry combined with fluorescence-based detection of illicit drugs -- Colorimetric detection of illicit drugs based on organic/inorganic chromophores -- Summary and outlooks -- References -- 9 - Fluorescence-based sensors for detection of illicit drugs -- Introduction -- Principle -- Advantages of using fluorescence-based sensors for detection -- Specific sensor types in fluorescence-based detection of illicit drugs -- Working principle -- Applications -- Critical analysis -- Molecularly imprinted polymers (MIPs) in fluorescence-based detection of illicit drugs -- Working principle -- Applications -- Critical analysis -- Quantum dots: Illuminating multiplicity in illicit drug detection -- Working principles -- Applications -- Critical analysis -- Comparative analysis of fluorescence-based sensors and conventional techniques -- Fluorescence-based sensors -- Mass spectrometry -- Nuclear magnetic resonance -- Raman spectroscopy -- Capillary electrophoresis -- Gas chromatography -- Liquid chromatography -- Breath test -- Blood test -- Urine test -- Saliva test -- Hair test. , Emerging trends and innovations in the detection of illicit drugs -- Regulatory and ethical considerations in the utilization of fluorescence-based sensors for drug detection -- Conclusion -- References -- 10 - Surface-enhanced Raman spectroscopy for detection of illicit drugs -- Introduction -- SERS-based detection of illicit drugs in biological fluid -- SERS-based detection of illicit drugs in wastewater -- Microfluidic integrated SERS platforms -- Conclusion and future perspective -- References -- 11 - Chromatography for detection of illicit drugs -- Introduction -- Primary ideas of chromatography on bioanalysis -- Applications -- Conclusions and future outlook -- References -- 12 - Devices used in the detection of illicit drugs -- Introduction -- Transformative role of portable sensor technologies -- The impact of portable sensor technologies in forensic toxicology -- Advancements in criminal investigations and public health -- Extending the reach and accessibility of forensic toxicology -- Worldwide impact of illicit drug use -- Rapid proliferation of illicit drugs -- Indirect consequences of drug abuse -- Collaborative approach to addressing illicit drug use -- Addressing the global impact of illicit drug use -- Evolving drug landscape in Europe -- Challenge of polydrug consumption -- Need for advancements in detection techniques -- Significance of biosensors in scientific and technical research -- Role of biosensors in addressing contemporary challenges -- Diverse types of biosensors -- Critical role of biosensors in scientific and technical advancements -- Electrochemical biosensors -- Impact and significance in various fields (Kroning and Wang, 2021) -- Specific applications and advantages (Zheng et al., 2013) -- Application of electrochemical sensors -- Fourier transform infrared spectroscopy. , Advantages and challenges of electrochemical sensors -- The global issue of illicit drug trade -- Consequences of illicit drug production and trafficking -- Negative health outcomes and policy responses -- Addressing the complexities of the illicit drug trade -- Impact of the pandemic on drug trafficking -- Comprehensive overview of illicit drugs and drug trafficking -- Effects on aquatic environment -- Importance of monitoring -- Challenges and urgent need for alternative detection tools -- Potential of sensor-based methods for detecting illicit drugs -- Sensor-based detection tools -- Importance of detecting illicit drugs in water samples -- Optical sensors for illicit drug detection -- Significance and categorization of detection methods -- References -- Further reading -- 13 - Rapid detection of illicit drugs in saliva -- Introduction -- Scope of study -- Sources of saliva in forensic investigation -- Use of saliva in various drugs detection -- Types of illicit drugs -- Challenges in rapid detection -- Collection techniques of saliva -- Storage and extraction of samples -- Detection techniques -- Chromatographic techniques -- Liquid chromatography-mass spectrometry (Case study-1) -- Gas chromatography-mass spectrometry (Case study-2) -- Spectroscopic techniques -- Infrared spectroscopy (IR) -- Ultraviolet spectroscopy (UV) -- Raman spectroscopy -- Microfluidics -- Quality assurance of drug testing -- Conclusion -- References -- 14 - Advantages of point-of-care detections -- Introduction -- Enhanced patient care and outcomes -- Rapid diagnostics -- Personalized treatment -- Remote monitoring -- Operational efficiency and cost savings -- Streamlined workflows -- Bedside decision-making -- Resource conservation -- Cost savings -- Improved infection control and public health -- Reduced transmission risk -- Outbreak management. , Surveillance and monitoring.

Sprache: Englisch