UID:
almafu_9959328078002883
Format:
1 online resource (xxxi, 346 pages, 8 unnumbered pages of plates) :
,
illustrations (some color)
ISBN:
0470052171
,
9780470052174
,
0470052155
,
9780470052150
,
0471770019
,
9780471770015
Content:
GSK-3 is a promising drug target that has been extensively tested, and shown great potential for treatment of diseases that have no current effective treatment? like Alzheimer?s, bipolar disorder, and cancer. GSK-3 and Its Inhibitors gathers and systematically analyzes a collection of studies and information in a single source and tool for biochemists and cell biologists.
Note:
Glycogen synthase kinase 3: an introductory synopsis -- Glycogen synthase kinase-3[beta] (GSK-3[beta]) a key signaling enzyme: a developmental neurobiological perspective -- Role of GSK-3/Shaggy in neuronal cell biology -- The crystal structures of glycogen synthase kinase 3 -- Kinase-kinase and site-site interactions in the phosphorylation of tau by GSK-3 -- GSK-3, a key player in Alzheimer's disease -- Glycogen synthase kinase 3 : a target for novel mood disorder treatments -- GSK-3 and stem cells -- Glycogen synthase kinase 3 : role in neurodegeneration and neuroprotection.
,
Protein kinase assays for drug discovery -- Animal models with modified expression of GSK-3 for the study of its physiology and of its implications in human pathologies -- Lithium, the seminal GSK-3 inhibitor -- Inhibition of GSK-3 as therapeutic strategy in disease : efficacy of AR-A014418 -- TDZD's: selective and ATP noncompetitive glycogen synthase kinase 3 inhibitors -- 3-amino pyrazoles as potent and selective glycogen kinase synthase (GSK-3) inhibitors -- Marine compounds as a new source for glycogen synthase kinase 3 inhibitors.
Additional Edition:
Print version: Glycogen synthase kinase 3 (GSK-3) and its inhibitors. Hoboken, N.J. : Wiley-Interscience, ©2006 ISBN 0471770019
Additional Edition:
ISBN 9780471770015
Language:
English
Keywords:
Electronic books.
;
Electronic books.
;
Electronic books.
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/0470052171
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/0470052171
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/0470052171
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