UID:
almafu_9959327131102883
Format:
1 online resource (xvi, 523 pages) :
,
illustrations
Edition:
2nd ed.
ISBN:
9780470119051
,
0470119055
,
9780470119044
,
0470119047
,
9780471471929
,
0471471925
Content:
This new edition of Whats Wrong With My Mouse? continues to provide the most thorough overview of mutant mouse technology and a readable introduction to the field of behavioural neuroscience as applied to behavioural phenotyping of transgenic and knockout mice.
Note:
Designer mice : scope and sourcebooks -- Of unicorns and chimeras : how to generate a transgenic or knockout mouse for behavioral phenotyping -- General health : give your mouse a physical -- Motor functions : open field, holeboard, rotarod, balance, grip, circadian activity, circling, stereotypy, ataxic gait, seizures -- Sensory abilities : olfaction, vision, hearing, taste, touch, nociception -- Learning and memory : Morris swim task, spatial mazes, cued and contextual conditioning, conditioned taste aversion, conditioned eyeblink, olfactory discrimination, social recognition, passive avoidance, schedule controlled operant tasks, motor learning, attention -- Feeding and drinking : daily consumption, restricted access, choice tests, microstructural analysis -- Reproductive behaviors : sexual and parental behaviors -- Social behaviors : social interaction, nesting, grooming, juvenile play, aggression -- Emotional behaviors : animal models of psychiatric disorders : mouse models of fear, anxiety, depression, schizophrenia -- Reward : self-administration of addictive drugs, conditioned place preference -- Neurodevelopment and neurodegeneration : assaying behaviours in infant, juvenile, and aged mice -- Putting it all together : choice of tests, order of testing, number of mice, equipment, housing and testing environment -- The next generation : conditional and inducible mutations, viral vector gene delivery, RNA silencing, quantitative trait loci analysis, DNA microarrays, chemical mutagenesis, gene therapy, ethical issues.
Additional Edition:
Print version: Crawley, Jacqueline N. What's wrong with my mouse?. Hoboken, N.J. : Wiley-Interscience, ©2007 ISBN 9780471471929
Additional Edition:
ISBN 0471471925
Language:
English
Keywords:
Electronic books.
;
Electronic books.
;
Electronic books.
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/0470119055
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/0470119055
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/0470119055
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