UID:
almafu_9959328015602883
Format:
1 online resource (xviii, 355 pages) :
,
illustrations
Edition:
Electronic reproduction. [Place of publication not identified] : HathiTrust Digital Library, 2010.
ISBN:
9780470092620
,
0470092629
Note:
Front Matter -- Sequence Analysis. Pairwise Global Alignment of Sequences -- Pairwise Local Alignment and Database Search -- Statistical Analysis -- Multiple Global Alignment and Phylogenetic Trees -- Scoring Matrices -- Profiles -- Sequence Patterns -- Structure Analysis. Structures and Structure Descriptions -- Superposition and Dynamic Programming -- Geometric Techniques -- Clustering: Combining Local Similarities -- Significance and Assessment of Structure Comparisons -- Multiple Structure Comparison -- Protein Structure Classification -- Sequence-Structureanalysis. Structure Prediction: Threading -- Appendix A: Basics in Mathematics, Probability and Algorithms -- Appendix B: Introduction to Molecular Biology -- References -- Index.
,
Sequence Analysis --
,
Pairwise Global Alignment of Sequences --
,
Alignment and Evolution --
,
A Scoring Scheme for the Model --
,
Finding Highest-Scoring Alignments with Dynamic Programming --
,
Determine H[subscript i, j] --
,
Use of matrices --
,
Finding the alignments that give the highest score --
,
Gaps --
,
Scoring Matrices --
,
Scoring Gaps: Gap Penalties --
,
Dynamic Programming for General Gap Penalty --
,
Dynamic Programming for Affine Gap Penalty --
,
Alignment Score and Sequence Distance --
,
Pairwise Local Alignment and Database Search --
,
The Basic Operation: Comparing Two Sequences --
,
Dot Matrices --
,
Filtering --
,
Repeating segments --
,
Dynamic Programming --
,
Initialization --
,
Finding the best local alignments --
,
Algorithms --
,
Scoring matrices and gap penalties --
,
Database Search: BLAST --
,
The procedure --
,
Preprocess the query: make the word list --
,
Scanning the database sequences --
,
Extending to HSP --
,
Introducing gaps --
,
Algorithm --
,
Statistical Analysis --
,
Hypothesis Testing for Sequence Homology --
,
Random generation of sequences --
,
Use of Z values for estimating the statistical significance --
,
Statistical Distributions --
,
Poisson probability distribution --
,
Extreme value distributions --
,
Theoretical Analysis of Statistical Significance --
,
The P value has an extreme value distribution --
,
Theoretical analysis for database search --
,
Probability Distributions for Gapped Alignments --
,
Assessing and Comparing Programs for Database Search --
,
Sensitivity and specificity --
,
Discrimination power --
,
Using more sequences as queries.
,
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Additional Edition:
Print version: Eidhammer, Ingvar. Protein bioinformatics. Chichester, West Sussex, England ; Hoboken, NJ : J. Wiley & Sons, ©2004 ISBN 0470848391
Language:
English
Keywords:
Electronic books.
;
Electronic books.
;
Electronic books.
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/9780470092620
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/9780470092620
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/9780470092620
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