UID:
edocfu_9959327339202883
Format:
1 online resource (xii, 308 pages) :
,
illustrations
ISBN:
0471460729
,
9780471460725
,
0471378283
,
9780471378280
,
0471220442
,
9780471220442
Content:
Solid-phase synthesis of carbohydrates presents unique challenges to synthetic chemists and currently represents one of the hottest areas of research in bioorganic chemistry. Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries addresses the exciting expectation that solid-phase assembly of oligosaccharides will have a fundamental impact on the field of glycobiology. This publication details the methodologies currently investigated for the attachment of carbohydrates to beads, synthesis including coupling strategies, and removal of the product from beads.
Note:
Solid-phase carbohydrate synthesis : the early work / Wilm-Christian Haase and Peter H. Seeberger -- The glycal assembly method on solid supports : synthesis of oligosaccharides and glycoconjugates / Pier F. Cirillo and Samuel J. Danishefsky -- The sulfoxide glycosylation method and its application to solid-phase oligosaccharide synthesis and the generation of combinatorial libraries / Carol M. Taylor -- The use of O-glycosyl trichloroacetimidates for the polymer-supported synthesis of oligosaccharides / Laurent Knerr and Richard R. Schmidt -- Synthesis of oligosaccharides on solid support using thioglycosides and pentenyl glycosides / Valentin Wittmann -- Solid-phase oligosaccharide synthesis using glycosyl phosphates / Wilm-Christian Haase, Obadiah J. Plante, and Peter H. Seeberger -- Stereoselective [beta]-mannosylation on polymer support / Yukishige Ito and Hiromune Ando -- Tools for "on-bead" monitoring and analysis in solid-phase oligosaccharide synthesis / Wilm-Christian Haase, Peter H. Seeberger, and Susan S. Pochapsky -- Polyethyleneglycol [omega]-monomethylether (MPEG)-supported solution-phase synthesis of oligosaccharides / Jiri J. Krepinsky and Stephen P. Douglas -- Two-direction glycosylations for the preparation of libraries of oligosaccharides / Geert-Jan Boons and Tong Zhu -- Carbohydrate libraries in solution using thioglycosides : from multistep synthesis to programmable, one-pot synthesis / Eric E. Simanek and Chi-Huey Wong -- Carbohydrate libraries by the random glycosylation approach / Osamu Kanie and Ole Hindsgaul -- Solid-phase synthesis of biologically important glycopeptides / Nicole Bézay and Horst Kunz -- Preparation and screening of glycopeptide libraries / Phaedria M. St. Hilaire, Koen M. Halkes, and Morten Meldal.
Additional Edition:
Print version: Solid support oligosaccharide synthesis and combinatorial carbohydrate libraries. New York : Wiley, ©2001 ISBN 0471378283
Language:
English
Keywords:
Electronic books.
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/0471220442
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