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  • 1
    Online Resource
    Online Resource
    Singapore :Jenny Stanford Publishing,
    UID:
    almahu_9949386196402882
    Format: 1 online resource (xii, 442 pages)
    ISBN: 9781003056690 , 1003056695 , 9781000092400 , 1000092402 , 9781000092448 , 1000092445 , 9781000092363 , 1000092364
    Content: Spherical nucleic acids (SNAs) comprise a nanoparticle core and a densely packed and highly oriented nucleic acid shell, typically DNA or RNA. They have novel architecture-dependent properties that distinguish them from all other forms of nucleic acids and make them useful in materials synthesis, catalysis, diagnostics, therapeutics, and optics/plasmonics. This book covers over two decades of the author's research on SNAs and their anisotropic analogues, including synthesis and fundamental properties, and applications in colloidal crystallization, adaptive matter, and nanomedicine, spanning extra- and intracellular diagnostics, gene regulation, and immunomodulation.
    Note: A DNA-Based Method for Rationally Assembling Nanoparticles into Macroscopic Materials (Nature, 1996). Nanoparticle-Based Bio-Barcodes for the Ultrasensitive Detection of Proteins (Science, 2003). Oligonucleotide-Modified Gold Nanoparticles for Intracellular Gene Regulation (Science, 2006). Nanoflares: Probes for Transfection and mRNA Detection in Living Cells (JACS, 2007). Cellular Response of Polyvalent Oligonucleotide-Gold Nanoparticle Conjugates (ACS Nano, 2010). Nanoparticle Superlattice Engineering with DNA (Science, 2011). Nucleic Acid-Modified Nanostructures as Programmable Atom Equivalents: Forging a New Table of Elements (Angew. Chem. Int. Ed., 2013). DNA-Mediated Engineering of Multicomponent Enzyme Crystals (PNAS, 2015). Clathrate Colloidal Crystals (Science, 2017).
    Language: English
    Keywords: Electronic books. ; Electronic books.
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