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  • 1
    Online Resource
    Online Resource
    Hoboken, N.J. :John Wiley & Sons,
    UID:
    almafu_9959327308002883
    Format: 1 online resource
    ISBN: 9780470939918 , 0470939915 , 0470939877 , 9780470939871 , 1118002253 , 9781118002254 , 1283239442 , 9781283239448
    Content: The book addresses the basics, applications, and manufacturing of plasmid biopharmaceuticals. The survey of the most relevant characteristics of plasmids provides the basics for designing plasmid products (applications) and processes (manufacturing). Key features that the authors include in the book are: i) consistency and clear line of direction, ii) an extensive use of cross-referencing between the individual chapters, iii) a rational integration of chapters, iv) appellative figures, tables and schemes, and v) an updated, but selected choice of references, with a focus on key papers.
    Note: Historical perspective -- Gene transfer with plasmid biopharmaceuticals -- Product and process development -- Structure -- Analytical characterization -- Delivery -- Ethical and safety issues -- Human and veterinary markets -- Human case studies : pandemic influenza and critical limb ischaemia -- Veterinary case studies : West Nile, infectious hematopoietic necrosis, and melanoma -- GMPS and validation -- Product specifications and quality control -- Cell culture -- An overview of downstream processing -- Primary isolation -- Intermediate recovery -- Final purification -- Process synthesis -- Concluding remarks and outlook.
    Additional Edition: Print version: Prazeres, Duarte Miguel F. Plasmid biopharmaceuticals. Hoboken, N.J. : John Wiley & Sons, ©2011 ISBN 9780470232927
    Language: English
    Keywords: Electronic books. ; Electronic books. ; Electronic books.
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