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  • 1
    Online Resource
    Online Resource
    Bielefeld : transcript Verlag
    UID:
    almahu_9948308201602882
    Edition: 1. Aufl.
    ISBN: 9783837632255 , 9783839432259
    Series Statement: Edition Politik
    Content: Long description: Radical ideologies may manifest differently at first, but they do follow a similar logic: truth claims, promises of salvation and a unifying common enemy. In Yemen's transition process today, the secessionist movement Al-Hirak has summoned the spirit of South Yemen, the only Marxist state in Arabia. This book meticulously describes how East Germany supported the implantation of this alien ideology in Yemen through its policy of »Socialist state- and nation-building«. In the same breath, the analysis captures the GDR's activities in the Middle East and their vital role in Moscow's Cold War strategy. Last but least, the study provides one of the few compact overviews of East German foreign policy in the English language of today.
    Content: Biographical note: Miriam M. Müller (Joint PhD) received her doctorate jointly from the Free University of Berlin, Germany, and the University of Victoria, Canada, in Political Science and International Relations. Specialized in the politics of the Middle East, she focuses on religious and political ideologies, international security, international development and foreign policy. Her current research is occupied with the role of religion, violence and identity in the manifestations of the »Islamic State«.
    Content: Quote: »Das Verdienst des Buches [ist es], gewohnte Forschungsperspektiven gewechselt und den Komplex des ostdeutsch-südjemenitischen Verhältnisses in einen größeren - primär das englischsprachige Publikum adressierenden - politikwissenschaftlich-theoretischen Kontext gerückt zu haben, indem er als 'socialist state- and nation-building' gefasst wurde.« Lutz Maeke, www.sehepunkte.de, 17/9 (2017) »Die Arbeit schließt eine wichtige Lücke in der Forschung zur DDR-Geschichte.« Michael Rohschürmann, Portal für Politikwissenschaft, 17.03.2016 Besprochen in: Jemen-Report (2016), Thanos Petouris The Chronicle, 01.04.2016
    Note: PublicationDate: 20151101
    Additional Edition: ISBN 9783839432259
    Language: English
    URL: Cover
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  • 2
    Online Resource
    Online Resource
    Bielefeld : transcript Verlag
    UID:
    almahu_9948308146602882
    Edition: 1. Aufl.
    ISBN: 9783837633160 , 9783839433164
    Series Statement: DiskursNetz
    Content: Long description: Die Berühmtheit eines Wissenschaftlers lässt sich nicht ausschließlich an der Anzahl der auf seine Werke getätigten Verweise ermessen. Auch die Vernachlässigung der Vollständigkeit eines Verweises auf den Urheber einer als grundlegend wahrgenommenen Idee stellt eine - wenn nicht gar die intensivste - Form der Anerkennung dar. Julia Richter ermittelt, mit welchen Strategien wissenschaftliches Prestige erzeugt wird. Im Zentrum ihrer Analyse stehen die Verweise auf Ferdinand de Saussure im Diskurs der romanistischen Linguistik. Die Studie entwickelt sogleich eine diskursanalytische Methode, die geeignet ist, Verweise in wissenschaftlichen Texten auf ihr Potential hin zu untersuchen, bestimmte Akteure des Diskurses aufzuzeigen und die Beziehungen zwischen diesen Diskursakteuren darzustellen.
    Content: Long description: How do linguists become famous? Or are they made famous by others? This volume sheds light on strategies of the construction of reputation by way of the discourses on Ferdinand de Saussure in linguistics and romance studies.
    Content: Biographical note: Julia Richter (Dr. phil.) lehrt Sprachwissenschaft am Institut für Romanische Sprachen und Kulturen an der Universität Duisburg-Essen. In ihrer Forschung beschäftigt sie sich unter anderem mit sprachlicher Stereotypisierung, Verweisforschung, Diskursanalyse und Wissenschaftssoziologie.
    Note: PublicationDate: 20151101
    Additional Edition: ISBN 9783839433164
    Language: English
    URL: Cover
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  • 3
    Online Resource
    Online Resource
    Bielefeld : transcript Verlag
    UID:
    almahu_9948308045402882
    Edition: 1. Aufl.
    ISBN: 9783837626506 , 9783839426500
    Series Statement: Kultur und soziale Praxis
    Content: Long description: Spatial and identity research operates with differentiations and relations. These are particularly useful heuristic tools when examining border regions where social and geopolitical demarcations diverge. Applying this approach, the authors of this volume investigate spatial and identity constructions in cross-border contexts as they appear in everyday, institutional and media practices. The results are discussed with a keen eye for obliquely aligned spaces and identities and relinked to governmental issues of normalization and subjectivation. The studies base upon empirical surveys conducted in Germany, France, Belgium and Luxembourg.
    Content: Biographical note: Christian Wille is a senior researcher at the University of Luxembourg and head of the network »UniGR-Center for Border Studies«. His research interests include cultural border studies, spatial, praxeological, and border theories as well as cross-border everyday life worlds. Rachel Reckinger (Dr.) is a sociologist and holds a post as a scientific project coordinator at the University of Luxembourg. Sonja Kmec (Prof. Dr.) teaches History and Cultural Studies at the University of Luxembourg. Markus Hesse (Prof. Dr.), geographer and spatial planner, is professor for urbanism at the University of Luxembourg.
    Content: Quote: »The collaborative publication of the University of Luxembourg is [...] a remarkable scientific project.« Peter Ulrich, PRAGREV, 5/1 (2017) »Die Lektüre ist ausgesprochen anregend und abwechslungsreich. Wer Anregungen sucht, was alltägliche Regionalisierung im Werlenschen Sinne konkret bedeutet, der bekommt hier reichhaltige Antworten. Wer sich für das Konzept der Grenze in seinem Facettenreichtum und in seiner konzeptionellen Tiefe interessiert, auch dem sei das Buch empfohlen.« Tobias Chilla, Raumforschung Raumordnung, 22.06.2016
    Note: PublicationDate: 20151101
    Additional Edition: ISBN 9783839426500
    Language: English
    URL: Cover
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  • 4
    Online Resource
    Online Resource
    Darmstadt : WBG
    UID:
    edoccha_9958971004102883
    Format: Online-Ressource (145 S.)
    Content: Long description: »Natur und Landschaft sind aufgrund ihres eigenen Wertes und als Grundlage für Leben und Gesundheit des Menschen auch in Verantwortung für die künftigen Generationen zu schützen.« So steht es im Gesetz zu Naturschutz und Landschaftspflege. Es besteht also eine gesetzliche Verpflichtung, die Natur zu erhalten. Doch was ist Naturschutz überhaupt, warum müssen manche Arten oder Lebensräume geschützt werden und wie funktioniert das in der Praxis? Welche Aspekte sind zu berücksichtigen, welche Prioritäten müssen gesetzt werden? Was verändert sich durch den globalen Wandel? Diese und viele weitere Fragen rund um das Thema Naturschutz beantworten Barbara Stammel und Bernd Cyffka in dem vorliegenden Band. Besonders Studierenden aus planungsbezogenen und umweltwissenschaftlichen Studiengängen bringen sie das Thema kurz gefasst und übersichtlich näher. Der Band versteht sich als Einstieg in die Thematik und ist somit für Studierende wie auch interessierte Laien geeignet.
    Content: Long description: Was ist Naturschutz, warum müssen manche Arten oder Lebensräume geschützt werden und wie funktioniert das in der Praxis? Diese und weitere Fragen beantworten die Autoren und bringen besonders Studierenden aus planungsbezogenen und umweltwissenschaftlichen Studiengängen, aber auch interessierten Laien das Thema kurz gefasst und übersichtlich näher.
    Content: Biographical note: Prof. Dr. Bernd Cyffka ist Professor für Angewandte Physische Geographie an der Katholischen Universität Eichstätt-Ingolstadt.
    Note: PublicationDate: 20151101
    Additional Edition: ISBN 3-534-72591-3
    Language: German
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  • 5
    Online Resource
    Online Resource
    San Rafael [California] (40 Oak Drive, San Rafael, CA, 94903, USA) :Morgan & Claypool Publishers, | Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) :IOP Publishing,
    UID:
    almahu_9947357766002882
    Format: 1 online resource (various pagings) : , illustrations (some color).
    ISBN: 9781681742571 , 9781681742595
    Series Statement: [IOP release 2]
    Content: The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo. This can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. The nanocarrier serves to protect the cargo from degradation by enzymes in the body, to enhance the solubility of insoluble drugs, to extend the circulation half-life, and to enhance its penetration and accumulation at the target site. Importantly, smart nanocarriers can be designed to be responsive to a specific stimulus, so that the cargo is only released or activated when desired. In this volume we cover smart nanocarriers that respond to internal stimuli that are intrinsic to the target site. These stimuli are specific to the cell type, tissue or organ type, or to the disease state (cancer, infection, inflammation etc). pH-responsive nanostructures can be used for cargo release in acidic endosomal compartments, in the lower pH of tumors, and for specific oral delivery either to the stomach or intestine. Nanocarriers can be designed to be substrates of a wide-range of enzymes that are over-expressed at disease sites. Oxidation and reduction reactions can be taken advantage of in smart nanocarriers by judicious molecular design. Likewise, nanocarriers can be designed to respond to a range of specific biomolecules that may occur at the target site. In this volume we also cover dual and multi-responsive systems that combine stimuli that could be either internal or external.
    Note: "Version: 20151101"--Title page verso. , "A Morgan & Claypool publication as part of IOP Concise Physics"--Title page verso. , Preface -- Acknowledgments -- Author biography -- 1. Introduction , 2. pH-sensitive micro/nanocarriers -- 2.1. Introduction -- 2.2. pH-sensitive nanocarriers -- 2.3. pH-sensitive micro/nanocarrier drug release mechanisms -- 2.4. Challenges and applications , 3. Enzyme-responsive nanocarriers -- 3.1. Introduction -- 3.2. Immobilized biocatalysts -- 3.3. Enzyme-responsive materials in drug delivery -- 3.4. Common enzyme-responsive materials , 4. Redox-responsive micro/nanocarriers -- 4.1. Redox-responsive nano drug/gene delivery systems -- 4.2. Nanogels -- 4.3. Polymersomes -- 4.4. Nanocapsules -- 4.5. Micelles , 5. Biomolecule-sensitive nanocarriers -- 5.1. Introduction -- 5.2. Adenosine-5'-triphosphate-responsive -- 5.3. Glucose-responsive -- 5.4. DNA-responsive -- 5.5. Reactive oxygen species-responsive -- 5.6. Glutathione-responsive -- 5.7. Receptor-responsive -- 5.8. Cytoplasm-responsive , 6. Dual/multi-stimuli-sensitive nanocarriers -- 6.1. Introduction -- 6.2. Dual stimuli-based delivery systems -- 6.3. Triple stimuli-based delivery systems -- 7. Future perspectives and the global drug delivery systems market. , Also available in print. , Mode of access: World Wide Web. , System requirements: Adobe Acrobat Reader.
    Additional Edition: Print version: ISBN 9781681742564
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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  • 6
    Online Resource
    Online Resource
    San Rafael [California] (40 Oak Drive, San Rafael, CA, 94903, USA) :Morgan & Claypool Publishers, | Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) :IOP Publishing,
    UID:
    edoccha_9958130646502883
    Format: 1 online resource (various pagings) : , illustrations (some color).
    ISBN: 0-7503-2808-8
    Series Statement: [IOP release 2]
    Content: The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo. This can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. The nanocarrier serves to protect the cargo from degradation by enzymes in the body, to enhance the solubility of insoluble drugs, to extend the circulation half-life, and to enhance its penetration and accumulation at the target site. Importantly, smart nanocarriers can be designed to be responsive to a specific stimulus, so that the cargo is only released or activated when desired. In this volume we cover smart nanocarriers that respond to internal stimuli that are intrinsic to the target site. These stimuli are specific to the cell type, tissue or organ type, or to the disease state (cancer, infection, inflammation etc). pH-responsive nanostructures can be used for cargo release in acidic endosomal compartments, in the lower pH of tumors, and for specific oral delivery either to the stomach or intestine. Nanocarriers can be designed to be substrates of a wide-range of enzymes that are over-expressed at disease sites. Oxidation and reduction reactions can be taken advantage of in smart nanocarriers by judicious molecular design. Likewise, nanocarriers can be designed to respond to a range of specific biomolecules that may occur at the target site. In this volume we also cover dual and multi-responsive systems that combine stimuli that could be either internal or external.
    Note: "Version: 20151101"--Title page verso. , "A Morgan & Claypool publication as part of IOP Concise Physics"--Title page verso. , Preface -- Acknowledgments -- Author biography -- 1. Introduction , 2. pH-sensitive micro/nanocarriers -- 2.1. Introduction -- 2.2. pH-sensitive nanocarriers -- 2.3. pH-sensitive micro/nanocarrier drug release mechanisms -- 2.4. Challenges and applications , 3. Enzyme-responsive nanocarriers -- 3.1. Introduction -- 3.2. Immobilized biocatalysts -- 3.3. Enzyme-responsive materials in drug delivery -- 3.4. Common enzyme-responsive materials , 4. Redox-responsive micro/nanocarriers -- 4.1. Redox-responsive nano drug/gene delivery systems -- 4.2. Nanogels -- 4.3. Polymersomes -- 4.4. Nanocapsules -- 4.5. Micelles , 5. Biomolecule-sensitive nanocarriers -- 5.1. Introduction -- 5.2. Adenosine-5'-triphosphate-responsive -- 5.3. Glucose-responsive -- 5.4. DNA-responsive -- 5.5. Reactive oxygen species-responsive -- 5.6. Glutathione-responsive -- 5.7. Receptor-responsive -- 5.8. Cytoplasm-responsive , 6. Dual/multi-stimuli-sensitive nanocarriers -- 6.1. Introduction -- 6.2. Dual stimuli-based delivery systems -- 6.3. Triple stimuli-based delivery systems -- 7. Future perspectives and the global drug delivery systems market. , Also available in print. , Mode of access: World Wide Web. , System requirements: Adobe Acrobat Reader.
    Additional Edition: Print version: ISBN 9781681742564
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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  • 7
    Online Resource
    Online Resource
    Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) :IOP Publishing,
    UID:
    edoccha_9958132266902883
    Format: 1 online resource (various pagings) : , illustrations (some color).
    ISBN: 0-7503-1054-5 , 0-7503-1112-6
    Series Statement: [IOP release 2]
    Content: The last few years have seen dramatic advances in the growth, fabrication and characterization of low-dimensional materials (such as graphene) and nanostructures (such as those formed from ultrathin films, wires, discs and other "dots"), formed either singly or in spatially periodic arrays. Most studies of these artificially engineered materials have been driven by their potential for device applications that involve smaller and smaller physical dimensions. In particular, the dynamical properties of these materials are of fundamental interest for the devices that involve high-frequency operation and/or switching. Consequently, the different excitations, vibrational, magnetic, optical, electronic, and so on, need to be understood from the perspective of how their properties are modified in finite structures especially on the nanometre length scale due to the presence of surfaces and interfaces. Recently, the patterning of nanoelements, into periodic and other arrays, has become a focus of intense activity, leading for example to photonic crystals and their analogues such as phononic and magnonic crystals where the control of the band gaps in the excitation spectrum is a basis for applications. The nonlinear properties of the excitations are increasingly a topic of interest, as well as the linear dynamics.
    Note: "Version: 20151101"--Title page verso. , Preface -- 1. Introduction -- 1.1. Types of excitations or waves -- 1.2. Survey of types of nanostructures -- 1.3. Experimental techniques for dynamic properties -- 1.4. Theoretical methods for dynamic properties -- 1.5. Photonic band gaps in periodic structures , 2. Phonons -- 2.1. Lattice dynamics for single surfaces and films -- 2.2. Elastic waves for single surfaces and films -- 2.3. Experimental studies -- 2.4. Phonons in multilayers and superlattices -- 2.5. Phononic crystals , 3. Magnons -- 3.1. Regimes of magnetization dynamics -- 3.2. Exchange-dominated waves in films -- 3.3. Dipolar and dipole-exchange waves in films -- 3.4. Experimental results for films and bilayers -- 3.5. Magnetic wires and stripes -- 3.6. Magnetic superlattices -- 3.7. Magnonic crystals , 4. Electronic and plasmonic excitations -- 4.1. Electronic surface states -- 4.2. Graphene sheets and ribbons -- 4.3. Bulk dielectric functions -- 4.4. 2D electron gas -- 4.5. Bulk-slab model for superlattice plasmons , 5. Polaritons -- 5.1. Phonon-polaritons -- 5.2. Plasmon-polaritons -- 5.3. Magnon-polaritons -- 5.4. Other types of polaritons , 6. Mixed excitations -- 6.1. Magnetoelastic waves -- 6.2. Piezoelectric waves -- 6.3. Ferroelectric materials -- 6.4. Multiferroic materials , 7. Nonlinear dynamics of excitations -- 7.1. Fundamentals of optical and magnetic nonlinearities -- 7.2. Applications to non-magnetic low-dimensional systems -- 7.3. Applications to magnetic low-dimensional systems -- Appendix. Some mathematical topics. , Also available in print. , Mode of access: World Wide Web. , System requirements: Adobe Acrobat Reader.
    Additional Edition: ISBN 0-7503-1055-3
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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  • 8
    Online Resource
    Online Resource
    Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) :IOP Publishing,
    UID:
    almahu_9947391666602882
    Format: 1 online resource (various pagings) : , illustrations (some color).
    ISBN: 9780750310543 , 9780750311120
    Series Statement: IOP expanding physics,
    Content: The last few years have seen dramatic advances in the growth, fabrication and characterization of low-dimensional materials (such as graphene) and nanostructures (such as those formed from ultrathin films, wires, discs and other "dots"), formed either singly or in spatially periodic arrays. Most studies of these artificially engineered materials have been driven by their potential for device applications that involve smaller and smaller physical dimensions. In particular, the dynamical properties of these materials are of fundamental interest for the devices that involve high-frequency operation and/or switching. Consequently, the different excitations, vibrational, magnetic, optical, electronic, and so on, need to be understood from the perspective of how their properties are modified in finite structures especially on the nanometre length scale due to the presence of surfaces and interfaces. Recently, the patterning of nanoelements, into periodic and other arrays, has become a focus of intense activity, leading for example to photonic crystals and their analogues such as phononic and magnonic crystals where the control of the band gaps in the excitation spectrum is a basis for applications. The nonlinear properties of the excitations are increasingly a topic of interest, as well as the linear dynamics.
    Note: "Version: 20151101"--Title page verso. , Preface -- 1. Introduction -- 1.1. Types of excitations or waves -- 1.2. Survey of types of nanostructures -- 1.3. Experimental techniques for dynamic properties -- 1.4. Theoretical methods for dynamic properties -- 1.5. Photonic band gaps in periodic structures , 2. Phonons -- 2.1. Lattice dynamics for single surfaces and films -- 2.2. Elastic waves for single surfaces and films -- 2.3. Experimental studies -- 2.4. Phonons in multilayers and superlattices -- 2.5. Phononic crystals , 3. Magnons -- 3.1. Regimes of magnetization dynamics -- 3.2. Exchange-dominated waves in films -- 3.3. Dipolar and dipole-exchange waves in films -- 3.4. Experimental results for films and bilayers -- 3.5. Magnetic wires and stripes -- 3.6. Magnetic superlattices -- 3.7. Magnonic crystals , 4. Electronic and plasmonic excitations -- 4.1. Electronic surface states -- 4.2. Graphene sheets and ribbons -- 4.3. Bulk dielectric functions -- 4.4. 2D electron gas -- 4.5. Bulk-slab model for superlattice plasmons , 5. Polaritons -- 5.1. Phonon-polaritons -- 5.2. Plasmon-polaritons -- 5.3. Magnon-polaritons -- 5.4. Other types of polaritons , 6. Mixed excitations -- 6.1. Magnetoelastic waves -- 6.2. Piezoelectric waves -- 6.3. Ferroelectric materials -- 6.4. Multiferroic materials , 7. Nonlinear dynamics of excitations -- 7.1. Fundamentals of optical and magnetic nonlinearities -- 7.2. Applications to non-magnetic low-dimensional systems -- 7.3. Applications to magnetic low-dimensional systems -- Appendix. Some mathematical topics. , Also available in print. , Mode of access: World Wide Web. , System requirements: Adobe Acrobat Reader.
    Additional Edition: Print version: ISBN 9780750310550
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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  • 9
    Online Resource
    Online Resource
    San Rafael [California] (40 Oak Drive, San Rafael, CA, 94903, USA) :Morgan & Claypool Publishers, | Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) :IOP Publishing,
    UID:
    almahu_9947357765902882
    Format: 1 online resource (various pagings) : , illustrations (some color).
    ISBN: 9781681742021 , 9781681740744
    Series Statement: [IOP release 2]
    Content: The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo, this can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. The nanocarrier serves to protect the cargo from degradation by enzymes in the body, to enhance the solubility of insoluble drugs, to extend the circulation half-life, and to enhance its penetration and accumulation at the target site. Importantly, smart nanocarriers can be designed to be responsive to a specific stimulus, so that the cargo is only released or activated when desired. In this volume we cover smart nanocarriers that respond to externally applied stimuli that usually involve application of physical energy. This physical energy can be applied from outside the body and can either cause cargo release, or can activate the nanostructure to be cytotoxic, or both. The stimuli covered include light of various wavelengths (ultraviolet, visible or infrared), temperature (increased or decreased), magnetic fields (used to externally manipulate nanostructures and to activate them), ultrasound, and electrical and mechanical forces. Finally we discuss the issue of nanotoxicology and the future scope of the field.
    Note: "Version: 20151101"--Title page verso. , "A Morgan & Claypool publication as part of IOP Concise Physics"--Title page verso. , Preface -- Acknowledgments -- Author biography -- 1. Introduction , 2. Light-sensitive nanocarriers -- 2.1. Introduction -- 2.2. Photo-sensitive nanoparticle-based carriers -- 2.3. Drug release via electrostatic assembly/disassembly (reversed surface charge) -- 2.4. Chromophore (or photosensitizer)-activated drug release -- 2.5. Photo-thermal-based drug release -- 2.6. Photo-sensitive caging/uncaging based on photolabile protecting groups -- 2.7. Photo-reduction-triggered drug release , 3. Temperature-sensitive nanocarriers -- 3.1. Introduction -- 3.2. LCST/UCST behavior -- 3.3. Thermo-responsive nanocarriers -- 3.4. Modulation of phase transition temperature in thermo-responsive nanoparticles -- 3.5. Sustained drug release by hydrophobic hydrogels -- 3.6. Cancer therapy via thermo-responsive nanocarriers -- 3.7. Temperature-responsive gene delivery systems -- 3.8. Thermo-sensitive co-delivery systems for cancer therapy -- 3.9. Temperature in photothermal-responsive micro/nano-systems , 4. Magnetic-responsive nanocarriers -- 4.1. Introduction -- 4.2. Magnetic-responsive particles for drug delivery -- 4.3. Magnetic-responsive particles for gene delivery , 5. Ultrasound-responsive nanocarriers -- 5.1. Introduction -- 5.2. Composition and structure of microbubbles -- 5.3. Ultrasound-responsive materials in drug delivery -- 5.4. Ultrasound-responsive materials in gene delivery , 6. Electrical and mechanical-responsive nanocarriers -- 6.1. Introduction -- 6.2. Electric field-sensitive polymers -- 6.3. Mechanical-responsive nanomaterials -- 7. Nanotoxicology and future scope for smart nanoparticles. , Also available in print. , Mode of access: World Wide Web. , System requirements: Adobe Acrobat Reader.
    Additional Edition: Print version: ISBN 9781681741383
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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  • 10
    Online Resource
    Online Resource
    San Rafael [California] (40 Oak Drive, San Rafael, CA, 94903, USA) :Morgan & Claypool Publishers, | Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) :IOP Publishing,
    UID:
    edoccha_9958130646402883
    Format: 1 online resource (various pagings) : , illustrations (some color).
    ISBN: 1-68174-258-6 , 1-68174-010-9 , 0-7503-2807-X
    Series Statement: [IOP release 2]
    Content: The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo, this can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. The nanocarrier serves to protect the cargo from degradation by enzymes in the body, to enhance the solubility of insoluble drugs, to extend the circulation half-life, and to enhance its penetration and accumulation at the target site. Importantly, smart nanocarriers can be designed to be responsive to a specific stimulus, so that the cargo is only released or activated when desired. In this volume we cover smart nanocarriers that respond to externally applied stimuli that usually involve application of physical energy. This physical energy can be applied from outside the body and can either cause cargo release, or can activate the nanostructure to be cytotoxic, or both. The stimuli covered include light of various wavelengths (ultraviolet, visible or infrared), temperature (increased or decreased), magnetic fields (used to externally manipulate nanostructures and to activate them), ultrasound, and electrical and mechanical forces. Finally we discuss the issue of nanotoxicology and the future scope of the field.
    Note: "Version: 20151101"--Title page verso. , "A Morgan & Claypool publication as part of IOP Concise Physics"--Title page verso. , Preface -- Acknowledgments -- Author biography -- 1. Introduction , 2. Light-sensitive nanocarriers -- 2.1. Introduction -- 2.2. Photo-sensitive nanoparticle-based carriers -- 2.3. Drug release via electrostatic assembly/disassembly (reversed surface charge) -- 2.4. Chromophore (or photosensitizer)-activated drug release -- 2.5. Photo-thermal-based drug release -- 2.6. Photo-sensitive caging/uncaging based on photolabile protecting groups -- 2.7. Photo-reduction-triggered drug release , 3. Temperature-sensitive nanocarriers -- 3.1. Introduction -- 3.2. LCST/UCST behavior -- 3.3. Thermo-responsive nanocarriers -- 3.4. Modulation of phase transition temperature in thermo-responsive nanoparticles -- 3.5. Sustained drug release by hydrophobic hydrogels -- 3.6. Cancer therapy via thermo-responsive nanocarriers -- 3.7. Temperature-responsive gene delivery systems -- 3.8. Thermo-sensitive co-delivery systems for cancer therapy -- 3.9. Temperature in photothermal-responsive micro/nano-systems , 4. Magnetic-responsive nanocarriers -- 4.1. Introduction -- 4.2. Magnetic-responsive particles for drug delivery -- 4.3. Magnetic-responsive particles for gene delivery , 5. Ultrasound-responsive nanocarriers -- 5.1. Introduction -- 5.2. Composition and structure of microbubbles -- 5.3. Ultrasound-responsive materials in drug delivery -- 5.4. Ultrasound-responsive materials in gene delivery , 6. Electrical and mechanical-responsive nanocarriers -- 6.1. Introduction -- 6.2. Electric field-sensitive polymers -- 6.3. Mechanical-responsive nanomaterials -- 7. Nanotoxicology and future scope for smart nanoparticles. , Also available in print. , Mode of access: World Wide Web. , System requirements: Adobe Acrobat Reader.
    Additional Edition: Print version: ISBN 9781681741383
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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