Umfang:
Online-Ressource (XI, 292 p. 3 illus., 2 illus. in color, online resource)
ISBN:
9783034807067
Serie:
Milestones in Drug Therapy
Inhalt:
This book provides a detailed overview of B-cell directed therapies in patients with rheumatic and systemic autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjögren syndrome, ANCA-associated vasculitis and cryoglobulinemia. Organ-specific autoimmune diseases are discussed with respect to the use of B-cell directed therapies in neurological autoimmune diseases and autoimmune cytopenias. Situations in which B-cell targeted therapy may be indicated are identified, thereby offering comprehensive support for therapeutic decisions on the basis of the latest published evidence. The book also offers a valuable reference tool for rheumatologists, internists, nephrologists, immunologists, and all specialists involved in the multidisciplinary care of patients with rheumatic and systemic autoimmune diseases
Anmerkung:
Description based upon print version of record
,
Historic outline of the development of drugs targeting B-cellsUnderstanding B-cell biology -- Pharmacological effects and mechanisms of action of agents blocking B cells -- Systemic lupus erythematosus: direct B-cell blocking -- Systemic lupus erythematosus: indirect B-cell blocking -- B-cell targeted therapies in rheumatoid arthritis -- B-cell targeted therapies in Primary Sjögren Syndrome -- Targeting B cells in ANCA-associated vasculitis -- B-cell targeted therapies in systemic sclerosis and inflammatory myopathies -- B-cell targeted therapies in cryoglobulinemia -- B-cell targeted therapies in autoimmune cytopenias and thrombosis -- Targeting B cells in neurological autoimmune diseases -- Targeting B cells in other systemic autoimmune diseases -- Safety of B-cell targeted therapies -- The future potential of biosimilars targeting B-cells.
Weitere Ausg.:
ISBN 9783034807050
Weitere Ausg.:
Erscheint auch als Druck-Ausgabe Drugs targeting B-Cells in autoimmune diseases Basel : Springer, 2014 ISBN 9783034807050
Weitere Ausg.:
ISBN 3034807058
Sprache:
Englisch
Schlagwort(e):
B-Zelle
;
Autoaggressionskrankheit
;
Targeted drug delivery
DOI:
10.1007/978-3-0348-0706-7
URL:
Volltext
(lizenzpflichtig)
Mehr zum Autor:
Khamashta, Munther A. 1957-
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