UID:
almafu_9958354751402883
Umfang:
1 online resource (491p.)
ISBN:
9783110809282
Anmerkung:
Frontmatter --
,
Preface --
,
Contents --
,
Contributors List --
,
1. Genetic Manipulation of Mammalian Cells --
,
1.1 Heterologous Expression of Genes in Mammalian Cells --
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1.2 Permanent Gene Expression in Mammalian Cells: Gene Transfer And Selection --
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1.3 Vectors for Gene Transfer and Expression in Animal Cells --
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1.4 Aspects of Gene Transfer and Gene Amplification in Recombinant Mammalian Cells --
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1.5 Isolation of Recombinant Cell Clones Exhibiting High-Level Expression of the Introduced Gene --
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1.6 Genetic Engineering of Antibodies and Derivatives from Mammalian Cells --
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1.7 Safety Evaluation of Products Derived From Mammalian Cell Lines --
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2. Biological Aspects of Animal Cells --
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2.1 Metabolic Control of Animal Cell Culture Processes --
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2.2 Glycosylation: A Post-Translational Modification --
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3. Cell Cultivation Technology --
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3.1 Bioreactors Designed for Animal Cells --
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3.2 Hydrodynamic Properties in Bioreactors --
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3.3 Kinetics and Simulation of Animal Cell Processes --
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3.4 On-line and Off-line Process Analysis --
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4. Down-Stream Processing --
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4.1 Principles of Product Extraction from Cell Culture and Purification for Pharmaceutical Proteins --
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4.2 Validation of Downstream Processes --
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Index --
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Backmatter
Weitere Ausg.:
ISBN 978-3-11-013403-2
Sprache:
Englisch
DOI:
10.1515/9783110809282
URL:
https://doi.org/10.1515/9783110809282
URL:
https://doi.org/10.1515/9783110809282
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