UID:
almahu_9949481306302882
Umfang:
1 online resource (352 p.)
ISBN:
9783110252361
,
9783110238570
Inhalt:
This book presents a survey of recent developments in protein biochemistry. Top researchers in the field of protein biochemistry describe modern methods to address the challenges of protein purification by three-phase partitioning, and their folding and degradation by the functions of chaperones. The significance of peptide purity for fibril formation is addressed as well as the use of target oriented peptide arrays in palliative approaches in mucoviszidose. The design and application of protein epitope mimetics just as the structural resolving of the misfolding of various mutant proteins in serpinopathies enlarge our tools in resolving pathophysiological imbalances.
Anmerkung:
Frontmatter --
,
Preface --
,
Editor. List of contributing authors --
,
Contents --
,
Abbreviations --
,
Acknowledgements --
,
1 Three-phase partitioning --
,
2 Folding and degradation functions of molecular chaperones --
,
3 Membrane protein folding in detergents --
,
4 Glycoprotein-folding quality control in the endoplasmic reticulum --
,
5 Conformational dynamics in peptides and proteins studied by triplet-triplet energy transfer --
,
6 Protein import into the intermembrane space of mitochondria --
,
7 On-membrane identification of gel-resolved proteins by matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS) --
,
8 Analysis of protein complexes using chemical cross-linking and mass spectrometry --
,
9 Single-crystal spectroscopy correlated with X-ray crystallography provides complementary perspectives on macromolecular function --
,
10 Wide-angle X-ray solution scattering (WAXS) --
,
11 Where purity matters: recombinant versus synthetic peptides in beta amyloid formation --
,
12 Chemical modifi cation of proteins in living cells --
,
13 Proteomics of human bronchoalveolar lavage fluid: discovery of biomarkers of chronic obstructive pulmonary disease (COPD) with difference gel electrophoresis (DIGE ) and mass spectrometry (MS) --
,
14 Proteomic analysis of Duchenne muscular dystrophy (DMD) --
,
15 Target-oriented peptide arrays in a palliative approach to cystic fibrosis (CF) --
,
16 Probing protein dynamics in vivo using backbone cyclization: bacterial acyl carrier protein as a case study --
,
17 The protein epitope mimetic approach to protein-protein interaction inhibitors --
,
18 The structural biology of α1-antitrypsin deficiency and the serpinopathies --
,
Index
,
Mode of access: Internet via World Wide Web.
,
In English.
In:
DGBA Backlist Complete English Language 2000-2014 PART1, De Gruyter, 9783110238570
In:
DGBA Backlist Medicine and Life Sciences 2000-2014 (EN), De Gruyter, 9783110238495
In:
DGBA Medicine and Life Sciences 2000 - 2014, De Gruyter, 9783110637915
In:
E-BOOK GESAMTPAKET / COMPLETE PACKAGE 2011, De Gruyter, 9783110261189
In:
E-BOOK PACKAGE ENGLISH LANGUAGES TITLES 2011, De Gruyter, 9783110261233
In:
E-BOOK PAKET SCIENCE TECHNOLOGY AND MEDICINE 2011, De Gruyter, 9783110261202
Weitere Ausg.:
ISBN 9783110252330
Sprache:
Englisch
Fachgebiete:
Biologie
Schlagwort(e):
Aufsatzsammlung
;
Aufsatzsammlung
;
Aufsatzsammlung
DOI:
10.1515/9783110252361
URL:
https://doi.org/10.1515/9783110252361
URL:
https://www.degruyter.com/isbn/9783110252361
URL:
https://doi.org/10.1515/9783110252361
URL:
Volltext
(URL des Erstveröffentlichers)
URL:
https://doi.org/10.1515/9783110252361
URL:
Volltext
(URL des Erstveröffentlichers)
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