UID:
almafu_9958125389102883
Umfang:
1 online resource (148 p.)
ISBN:
9783318010510
,
3318010510
,
9781417523610
,
1417523611
Serie:
Interdisciplinary topics in gerontology, vol. 33
Inhalt:
With the remarkable increase in life expectancy in recent years, overall numbers of older individuals living with disability and functional dependence are likely to increase. Age-related changes and diseases involving the peripheral nervous system, particularly its autonomic elements, frequently play determining roles in late life health and functional independence. While basal sympathetic activity increases with normative aging, there is evidence of considerable dysregulation of the ability of the aging sympathetic nervous system to respond to a variety of challenges. In this book, investigators from several different disciplines discuss aging of the autonomic nervous system from a variety of perspectives. Given the fact that aging of the parasympathetic elements of the autonomic nervous system is not nearly as well understood as that of its sympathetic portions, greater emphasis has been placed on the latter. The topics of this volume provide an excellent overview addressing a number of clinically important questions by highlighting key clinical and basic research studies. This book should be of great interest for general physicians, specialists in geriatrics, and neurologists.
Anmerkung:
Description based upon print version of record.
,
""Contents""; ""Preface""; ""References""; ""Age-Related Sympathetic Autonomic Neuropathology""; ""The Aging Human Autonomic Nervous System""; ""Clinical Studies""; ""Neuropathology""; ""The Autonomic Nervous System of Aged Experimental Animals""; ""Pathophysiological and Biochemical Studies""; ""Neuropathology""; ""Postulated Mechanisms of Autonomic Nervous System Damage with Age""; ""Oxidative Injury""; ""Deficiency of Neurotrophic Substances and Aging in the Peripheral Nervous System""; ""Neurotrophic Substances in Excess as a Pathogenetic Mechanism for NAD""
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""Regenerative Mechanisms (Axonal Regeneration, Collateral Axonal Sprouting, Synaptic Plasticity)""""Synaptic Degradation of Organelles""; ""Extracellular Matrix""; ""Abnormal Calcium Dynamics""; ""Acknowledgements""; ""References""; ""Clinical and Therapeutic Implications of Aging Changes in Autonomic Function""; ""Aging Changes in -Adrenoceptor Responsiveness""; ""Aging Changes in Baroreflex Sensitivity""; ""Increased Sympathetic Nervous System Activity""; ""Autonomic Dysfunction in Association with Central Nervous System Disease""; ""Summary""; ""References""
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""Normal and Pathological Changes in Cardiovascular Autonomic Function with Age""""Normal Changes in Cardiovascular Function""; ""Heart Rate""; ""Blood Pressure""; ""Systolic Function""; ""Diastolic Function""; ""Diagnosis and Management for Specific Cardiovascular Diseases Related to Autonomic Dysfunction""; ""Syncope""; ""Heart Failure and Altered Neurohumoral Response""; ""References""; ""The Autonomic Nervous System and Blood Pressure Regulation in the Elderly""; ""Autonomic Nervous System Physiology""; ""Aging and the Autonomic Nervous System""; ""Acknowledgement""; ""References""
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""Aging, Carbohydrate Metabolism and the Autonomic Nervous System""""Effect of Aging on Carbohydrate Metabolism""; ""Potential Mechanisms to Explain Impaired Carbohydrate Metabolism with Aging""; ""Age-Related Changes of the Autonomic Nervous System � A Possible Explanation?""; ""Stress-Induced Hyperglycemia in the Aged Population""; ""Aging and the Autonomic Response to Carbohydrate Intake""; ""Aging, Adrenergic Stimulation and Glucose Production""; ""Aging, Adrenergic Stimulation and Insulin Secretion""; ""Aging, Adrenergic Stimulation, and Insulin-Mediated Glucose Uptake""
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""Aging, Adrenergic Stimulation and Non-Insulin-Mediated Glucose Uptake""""Effect of Aging on the Adrenergic Response to Hypoglycemia""; ""Conclusion""; ""References""; ""Aging and the Gastrointestinal Tract""; ""The Aging Esophagus""; ""The Aging Stomach""; ""Aggressive Factors""; ""Defensive Factors""; ""Motility""; ""Aging and the Small Intestine""; ""The Aging Colon""; ""References""; ""Structure and Function of the Aged Bladder""; ""Factors Affecting Continence in the Elderly""; ""Physiologic and Functional Changes in the Aged Human Bladder""; ""Normal Neural Control of the Bladder""
,
""Transmitters and Receptors""
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English
Weitere Ausg.:
ISBN 9783805576857
Weitere Ausg.:
ISBN 3805576854
Sprache:
Englisch
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