UID:
almafu_9959329146102883
Umfang:
1 online resource (xxxi, 575 pages) :
,
illustrations
ISBN:
9783527607495
,
3527607498
,
9783527312573
,
3527312579
,
3527608001
,
9783527608003
Inhalt:
The first authoritative overview of past and current strategies for successful drug development by analog generation, this unique resource spans all important drug classes and all major therapeutic fields, including histamine antagonists, ACE inhibitors, beta blockers, opioids, quinolone antibiotics, steroids and anticancer platinum compounds. Of the 19 analog classes presented in detail, 9 are described by the scientists who discoverd them. The book includes a table of the most successful drug analogs as based on the IMS ranking and compares them in terms of chemical structure, mode of action.
Anmerkung:
Analogue-based Drug Discovery; Contents; Preface; Introduction; List of Contributors; Abbreviations; Part I General Aspects of Analogue-Based Drug Discovery; 1 Analogues as a Means of Discovering New Drugs; 2 Drug Likeness and Analogue-Based Drug Discovery; 3 Privileged Structures and Analogue-Based Drug Discovery; Part II Selected Examples of Analogue-Based Drug Discoveries; 1 Development of Anti-Ulcer H(2)-Receptor Histamine Antagonists; 2 Esomeprazole in the Framework of Proton-Pump Inhibitor Development; 3 The Development of a New Proton-Pump Inhibitor: The Case History of Pantoprazole.
Weitere Ausg.:
Print version: Analogue-based drug discovery. Weinheim : Wiley-VCH, ©2006 ISBN 3527312579
Sprache:
Englisch
Schlagwort(e):
Electronic books.
;
Electronic books.
;
Electronic books.
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/3527608001
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/3527608001
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/3527608001
Bookmarklink
