UID:
almafu_9959327492702883
Umfang:
1 online resource.
ISBN:
9783527688081
,
3527688080
,
9783527688104
,
3527688102
Serie:
Advanced biotechnology
Inhalt:
A review of the interdisciplinary field of synthetic biology, from genome design to spatial engineeringWritten by an international panel of experts, Synthetic Biology draws from various areas of research in biology and engineering and explores the current applications to provide an authoritative overview of this burgeoning field. The text reviews the synthesis of DNA and genome engineering and offers a discussion of the parts and devices that control protein expression and activity. The authors include information on the devices that support spatial engineering, RNA switches and explore the early applications of synthetic biology in protein synthesis, generation of pathway libraries, and immunotherapy. Filled with the most recent research, compelling discussions, and unique perspectives, Synthetic Biology offers an important resource for understanding how this new branch of science can improve on applications for industry or biological research. Advanced BiotechnologyBiotechnology is a broad, interdisciplinary field of science, combining biological sciences and relevant engineering disciplines, that is becoming increasingly important as it benefits the environment and society. Recent years have seen substantial advances in all areas of biotechnology, resulting in the emergence of brand new fields. To reflect this progress, Sang Yup Lee (KAIST, South Korea), Jens Nielsen (Chalmers University, Sweden), and Gregory Stephanopoulos (MIT, USA) have joined forces as the editors of a new Wiley-VCH book series. Advanced Biotechnology will cover all pertinent aspects of the field and each volume will be prepared by eminent scientists who are experts on the topic in question.
Anmerkung:
Front Matter -- Part I. Competition and the Future of Reading and Writing DNA / Robert Carlson -- Trackable Multiplex Recombineering (TRMR) and Next-Generation Genome Design Technologies: Modifying Gene Expression in E. coli by Inserting Synthetic DNA Cassettes and Molecular Barcodes / Emily F Freed, Gur Pines, Carrie A Eckert, Ryan T Gill -- Site-Directed Genome Modification with Engineered Zinc Finger Proteins / Lauren E Woodard, Daniel L Galvan, Matthew H Wilson -- Rational Efforts to Streamline the Escherichia coli Genome / Gabriella Balikó, Viktor Vernyik, Ildikó Karcagi, Zsuzsanna Györfy, Gábor Draskovits, Tamás Fehér, György Pósfai -- Functional Requirements in the Program and the Cell Chassis for Next-Generation Synthetic Biology / Antoine Danchin, Agnieszka Sekowska, Stanislas Noria -- Part II. Constitutive and Regulated Promoters in Yeast: How to Design and Make Use of Promoters in S. cerevisiae / Diana S M Ottoz, Fabian Rudolf -- Splicing and Alternative Splicing Impact on Gene Design / Beatrix Suess, Katrin Kemmerer, Julia E Weigand -- Design of Ligand-Controlled Genetic Switches Based on RNA Interference / Shunnichi Kashida, Hirohide Saito -- Small Molecule-Responsive RNA Switches (Bacteria): Important Element of Programming Gene Expression in Response to Environmental Signals in Bacteria / Yohei Yokobayashi -- Programming Gene Expression by Engineering Transcript Stability Control and Processing in Bacteria / Jason T Stevens, James M Carothers -- Small Functional Peptides and Their Application in Superfunctionalizing Proteins / Sonja Billerbeck -- Part III. Metabolic Channeling Using DNA as a Scaffold / Mojca Benčina, Jerneja Mori, Rok Gaber, Roman Jerala -- Synthetic RNA Scaffolds for Spatial Engineering in Cells / Gairik Sachdeva, Cameron Myhrvold, Peng Yin, Pamela A Silver -- Sequestered: Design and Construction of Synthetic Organelles / Thawatchai Chaijarasphong, David F Savage -- Part IV. Cell-Free Protein Synthesis: An Emerging Technology for Understanding, Harnessing, and Expanding the Capabilities of Biological Systems / Jennifer A Schoborg, Michael C Jewett -- Applying Advanced DNA Assembly Methods to Generate Pathway Libraries / Dawn T Eriksen, Ran Chao, Huimin Zhao -- Synthetic Biology in Immunotherapy and Stem Cell Therapy Engineering / Patrick Ho, Yvonne Y Chen -- Part V. Synthetic Biology: From Genetic Engineering 2.0 to Responsible Research and Innovation / Lei Pei, Markus Schmidt.
Weitere Ausg.:
Print version: Synthetic biology. Weinheim, Germany : Wiley-VCH, [2018] ISBN 3527330755
Weitere Ausg.:
ISBN 9783527330751
Sprache:
Englisch
Schlagwort(e):
Electronic books.
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/9783527688104
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