Umfang:
Online-Ressource (XV, 329 p. 29 illus, digital)
ISBN:
9783540343448
Serie:
Current Topics in Microbiology and Immunology 312
Inhalt:
Kaposi sarcoma (KS) emerged in 1981 from being a rare curiosity mainly affecting children in sub-Saharan Africa and elderly men in Eastern Europe. The epidemiology of KS in HIV+ and HIV- individuals proposed that an infectious agent, other than HIV-1, is involved in the pathogenesis of this tumor. In 1994, Chang and Moore (Columbia University, NYC), used representational difference analysis to identify sequences of a novel human herpesvirus (Kaposi sarcoma herpesvirus, KSHV) in AIDS-related KS. Phylogenetically, the virus is closely related to herpesviruses in pan troglodytes and gorilla. Mole
Anmerkung:
Includes bibliographical references and index
,
CONTENTS; Modern Evolutionary History of the Human KSHV Genome; Rhesus Monkey Rhadinovirus: A Model for the Study of KSHV; The Rta/Orf50 Transactivator Proteins of the Gamma-Herpesviridae; Structure and Function of Latency-Associated Nuclear Antigen; The KSHV and Other Human Herpesviral G Protein-Coupled Receptors; Regulation of KSHV Lytic Gene Expression; Kaposi Sarcoma Herpesvirus-Encoded Interferon Regulator Factors; Endothelial Cell- and Lymphocyte-Based In Vitro Systems for Understanding KSHV Biology; KSHV After an Organ Transplant: Should We Screen?
,
Kaposi Sarcoma-Associated Herpesvirus and Other Viruses in Human LymphomagenesisThe Use of Antiviral Drugs in the Prevention and Treatment of Kaposi Sarcoma, Multicentric Castleman Disease and Primary Effusion Lymphoma; Interactions Between HIV-1 Tat and KSHV; Subject Index
Weitere Ausg.:
ISBN 9783540343431
Weitere Ausg.:
Buchausg. u.d.T. Kaposi sarcoma herpesvirus: new perspectives ; with 14 tables Berlin : Springer, 2007 ISBN 3540343431
Weitere Ausg.:
ISBN 9783540343431
Sprache:
Englisch
Fachgebiete:
Biologie
,
Medizin
Schlagwort(e):
Kaposi-Syndrom
;
Herpesviren
;
Kaposi-Syndrom
;
Kaposi-Syndrom
;
Herpesviren
;
Aufsatzsammlung
DOI:
10.1007/978-3-540-34344-8
URL:
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