Format:
Online-Ressource (XVI, 445 p., 47 illus, digital)
ISBN:
9783540748915
Series Statement:
Biological and Medical Physics, Biomedical Engineering
Content:
This monograph addresses, in a systematic and pedagogical manner, the mathematical methods and the algorithms required to deal with the molecularly based problems of bioinformatics. The book will be useful to students, research scientists and practitioners of bioinformatics and related fields, especially those who are interested in the underlying mathematical methods and theory. Among the methods presented in the book, prominent attention is given to pair-wise and multiple sequence alignment algorithms, stochastic models of mutations, modulus structure theory and protein configuration analysis. Strong links to the molecular structures of proteins, DNA and other biomolecules and their analyses are developed. In particular, for proteins an in-depth exposition of secondary structure prediction methods should be a valuable tool in both molecular biology and in applications to rational drug design. The book can also be used as a textbook and for this reason most of the chapters include exercises and problems at the level of a graduate program in bioinformatics.
Note:
Includes bibliographical references and index
,
Front Matter; Introduction; Stochastic Models of Mutations and Structural Analysis; Modulus Structure Theory; Super Pairwise Alignment; Multiple Sequence Alignment; Network Structures of Multiple Sequences Induced by Mutation; Alignment Space; Background Information Concerning the Properties of Proteins; Informational and Statistical Iterative Analysis of Protein Secondary Structure Prediction; Three-Dimensional Structure Analysis of the Protein Backbone and Side Chains; Alignment of Primary and Three-Dimensional Structures of Proteins; Depth Analysis of Protein Spatial Structure
,
Analysis of the Morphological Features of Protein Spatial StructureSemantic Analysis for Protein Primary Structure; Back Matter
Additional Edition:
ISBN 9783540748908
Additional Edition:
Buchausg. u.d.T. Shen, Shiyi Theory and mathematical methods in bioinformatics Berlin : Springer, 2008 ISBN 3540748903
Additional Edition:
ISBN 9783540748908
Language:
English
Subjects:
Biology
Keywords:
Bioinformatik
;
Mathematische Methode
DOI:
10.1007/978-3-540-74891-5
Author information:
Tuszynski, Jack A. 1956-
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