Format:
Online-Ressource (XI, 188p, digital)
ISBN:
9783642168338
Series Statement:
Biology of Extracellular Matrix
Content:
Initially believed to be inactive molecules, glycans are now considered essential for life, both under normal and pathological conditions. This volume of the series Biology of Extracellular Matrix reviews the most recent findings on the role of glycans in the development of diseases and the possible therapeutic use of this class of molecules. It shows how the interaction of glycans with growth factors, growth factor binding proteins, extracellular proteases, protease inhibitors, chemokines, morphogens, and adhesive proteins regulates inflammation, infection, cancer, atherosclerosis, thrombosis and embryonic stem cell biology. Furthermore, an extensive survey about the structure and pharmacological effects of unique marine glycosaminoglycans is discussed as well as the possibility of using these glycans as therapeutic agents.
Note:
Includes bibliographical references and index
,
Heparan sulfate proteoglycan in inflammation and angiogenesis / Lianchun WangHeparan sulfate proteoglycans in infection / Allison H. Bartlett and Pyong Woo Park -- Glycans in cancer / Lubor Borsig -- Glycosaminoglycans in atherosclerosis and thrombosis / C.P. Vicente, J.A.P. Godoy, and C.C. Werneck -- Glycans in embryonic stem cells / Claire Pickford ... [et al.] -- Heparan sulfate proteoglycans in cancer therapy / Ezeddin Salem Gassar, Sherif A. Ibrahim, and Martin Götte -- Structure and biological activities of glycosaminoglycan analogs from marine invertebrates : new therapeutic agents? Eliene O. Kozlowski ... [et al.].
Additional Edition:
ISBN 9783642168321
Additional Edition:
Buchausg. u.d.T. Glycans in diseases and therapeutics Berlin : Springer, 2011 ISBN 9783642168321
Additional Edition:
ISBN 3642168329
Language:
English
Keywords:
Glykokonjugate
;
Pathogenese
;
Aufsatzsammlung
DOI:
10.1007/978-3-642-16833-8
URL:
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