Umfang:
Online-Ressource (XVIII, 179p. 52 illus., 15 illus. in color, digital)
ISBN:
9783642214738
Serie:
SpringerLink
Inhalt:
Hong Gil Nam
Inhalt:
The complexity of human uterine function and regulation is one of the great wonders of nature and represents a daunting challenge to unravel. This book is dedicated to the biomechanical modeling of the gravid human uterus and gives an example of the application of the mechanics of solids and the theory of soft shells to explore medical problems of labor and delivery. After a brief overview of the anatomy, physiology and biomechanics of the uterus, the authors focus mainly on electromechanical wave processes, their origin, dynamics, and neuroendocrine and pharmacological modulations. In the las
Anmerkung:
Includes bibliographical references and indexes
,
CONTENTS; 1 Biological Preliminaries; 1.1 The Uterus; 1.2 Functional Unit; 1.3 Electrophysiological Properties; 1.4 Neuroendocrine Modulators; 1.5 Coupling Phenomenon; 1.6 Crosstalk Phenomena; 2 Models of the Gravid Uterus; 2.1 Biological Changes in Pregnant Uterus; 2.2 Mechanical Models of the Gravid Uterus; 2.3 Models of Myoelectrical Activity; 3 A Dynamic Model of the Fasciculus; 3.1 Formulation of the Model; 3.2 Effect of Changes in the Ionic Environment on MyoelectricalActivity; 3.3 Effects of Ion Channel Agonists/Antagonists; 4 General Theory of Thin Shells; 4.1 Basic Assumptions
,
4.2 Geometry of the Surface4.3 Tensor of Affine Deformation; 4.4 Equations of Continuity of Deformations; 4.5 Equations of Equilibrium; 5 Essentials of the Theory of Soft Shells; 5.1 Deformation of the Shell; 5.2 Principal Deformations; 5.3 Membrane Forces; 5.4 Principal Membrane Forces; 5.5 Equations of Motion in General Curvilinear Coordinates; 5.6 Nets; 5.7 Corollaries of the Fundamental Assumptions; 6 Continual Model of the Myometrium; 6.1 Basic Assumptions; 6.2 Model Formulation; 6.3 Biofactor Z kl; 6.4 Special Cases; 7 Models of Synaptic Transmission and Regulation
,
7.1 System Compartmentalization7.2 cAMP-Dependent Pathway; 7.3 PLC Pathway; 7.4 Co-transmission in Myometrium; 8 Pharmacology of Myometrial Contractility; 8.1 Classes of Drugs; 8.2 Current Therapies of Myometrial Dysfunction; 8.3 Model of Competitive Antagonist Action; 8.4 Model of Allosteric Interaction; 8.5 Allosteric Modulation of Competitive Agonist/Antagonist Action; 8.6 Model of PDE-4 Inhibitor; 9 Gravid Uterus as a Soft Biological Shell; 9.1 Fundamental Assumptions; 9.2 Model of the Gravid Uterus; 9.3 Numerical Simulations; 10 Biomechanics of the Gravid Uterus in Perspective
,
10.1 Ontology of Models10.2 Applications, Pitfalls, and Problems; References; Index
Weitere Ausg.:
ISBN 9783642214721
Weitere Ausg.:
Buchausg. u.d.T. Miftahof, Roustem N., 1957 - Biomechanics of the gravid human uterus Berlin : Springer, 2011 ISBN 9783642214721
Weitere Ausg.:
ISBN 364221472X
Sprache:
Englisch
Schlagwort(e):
Gebärmutter
;
Schwangerschaft
;
Biomechanik
;
Elektrophysiologie
;
Mathematisches Modell
;
Gebärmutter
;
Schwangerschaft
;
Biomechanik
;
Elektrophysiologie
;
Mathematisches Modell
DOI:
10.1007/978-3-642-21473-8
URL:
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