UID:
edoccha_9959238938102883
Umfang:
1 online resource (xxi, 253 pages) :
,
illustrations (some color)
ISBN:
0-12-800073-2
Serie:
Gale eBooks
Inhalt:
Through the use of extended graphical abstracts and some traditional text-only abstracts this collection provides, a record of and roadmap to, the research presented at The Tenth International Catecholamine Symposium (XICS) held in September of 2012. Organized around ten general themes, each is introduced by a short overview identifying interesting research programs, results and potential areas of growth. The collection is a roadmap to key research and future opportunities for new catecholamine research programs and will be of interest to neuroscientists and clinical neurologists interested
Anmerkung:
Description based upon print version of record.
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Front Cover; Catecholamine Research in the 21st Century; Copyright Page; Contents; Preface; THEME A: CATECHOLAMINE BIOSYNTHESIS AND STORAGE; 1. Genetic Manipulation of Catecholamine Signaling in the Mouse; 2. AADC Deficiency: Occurring in Humans; Modeled in Rodents; Treated in Patients; 3. Tyrosine Hydrolylase and Dopamine Beta-Hydroxylase: Role of Common Genetic Variation in Adrenergic Responses to Stress and ...; 4. Pharmacokinetic and Pharmacodynamic Properties of Etamicastat, a New DBH Inhibitor: Comparison to Nepicastat
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5. Estradiol-Mediated Regulation of Gene Expression of Catecholamine Biosynthetic Enzymes: The Role of Membrane-Initiated Sign...6. Structural Basis for Regulation of Tyrosine Hydroxlyase by the Catecholamines; 7. Unique Regulation of TH Gene Expression in Midbrain Dopamine Neurons; 8. Intracellular Stability of Tyrosine Hydroxylase: Phosphorylation and Proteasomal Digestion of the Enzyme; 9. The Peripheral Interaction of Tyrosine Hydroxylase and 14-3-3γ with Negatively Charged Phospholipidic Membranes; References
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10. Dynamic Regulation of Tyrosine Hydroxylase Gene Expression by Key Fate-Determining Transcription Factors during Dopaminergi...11. Analysis of Tyrosine Hydroxylase Isoforms and Phosphorylation in Parkinson's Disease; 12. Non-dopaminergic Neurons Partly Expressing Dopaminergic Phenotype: Functional Significance and Regulation; 13. Developing Brain as an Endocrine Organ: Catecholamines Secretion and Endocrine Action; 14. Brainstem DOPAergic System; 15. Imaging Norepinephrine Transporters in Humans; Translational Research with PET
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16. Imaging the Vesicular Monoamine Transporter (VMAT2) in Neurodegenerative Diseases17. GTP Cyclohydrolase Regulation: Implications for Brain Development and Function; 18. Neonatal Diagnosis of Menkes Disease by a Pattern of Plasma Catechols; 19. Catecholamine Metabolites Affected by the Copper-Dependent Enzyme Dopamine-Beta-Hydroxylase Provide Sensitive Blood and Csf...; 20. Are the Enzymes of the Catecholamine Biosynthetic Pathway Locally Synthesized in the Axon?
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21. Effects of Missense Mutations in Tyrosine Hydroxylase (TH) Found in Patients with Neurological Disorders Attributed to TH D...22. Tetrahydrobiopterin Deficiency Impairs Postnatal Increase of TH Protein via Insufficient Dopamine Biosynthesis; 23. Selective Ablation of Dopamine Beta-Hydroxylase Neurons (Subpopulation of TH Neurons) in the Brain: New Insights into Brain...; 24. Neural Circuit Mechanism for Learning Dependent on Dopamine Transmission: Roles of Striatal Direct and Indirect Pathways in...
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25. Regulation of Tyrosine Hydroxylase by Ser19-Phosphorylation-Dependent Binding to 14-3-3γ
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English
Weitere Ausg.:
ISBN 0-12-800044-9
Sprache:
Englisch
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