UID:
edoccha_9960074174602883
Format:
1 online resource (1184 p.)
ISBN:
0-12-800375-8
Note:
Description based upon print version of record.
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Front Cover; Neuropathology of Drug Addictions and Substance Misuse Volume 2: Stimulants, Club and Dissociative Drugs, Hallucinogens, Steroids, Inhalants, and International Aspects; How To use; Neuropathology of Drug Addictions and Substance Misuse Volume 2: Stimulants, Club and Dissociative Drugs, Hallucinogens, Steroids, Inhalants, and International Aspects; Copyright; Contents; List of Contributors; Preface; Acknowledgments; I - Stimulants; A - General Aspects; 1 - Cocaine: Usage, Misuse, and Addiction Processes. An Overview; INTRODUCTION; CLINICAL PERSPECTIVES ON COCAINE ABUSE
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Historical Cocaine UseClinical Features of Cocaine Addiction; Genetic and Environmental Factors Contributing to Individual Susceptibility to Cocaine Dependence: Endogenous Opioid System and ...; MOLECULAR NEUROBIOLOGY OF COCAINE ADDICTION; Historical Research on the Mechanism of Action of Cocaine; Development of Humanized Behavioral Models of Cocaine Addiction; Cocaine-Induced Neurobiological Adaptations and Gene Expression Changes; CONCLUSIONS; APPLICATIONS TO OTHER DRUGS OF ABUSE; DEFINITION OF TERMS; KEY FACTS OF THE STATISTICS OF COCAINE USE IN THE UNITED STATES; SUMMARY POINTS
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REFERENCES2 - Amphetamine Usage, Misuse, and Addiction Processes: An Overview; INTRODUCTION; USAGE, MISUSE, AND ADDICTION PROCESSES; Applications to Other Addictions and Substance Misuse; DEFINITION OF TERMS; KEY FACTS; Key Facts of ADHD; Key Facts of Dopamine; SUMMARY POINTS; REFERENCES; 3 - Mephedrone: An Overview of Its Neurotoxic Potential; INTRODUCTION; Β-KETOAMPHETAMINES, AMPHETAMINES AND THE POTENTIAL FOR NEUROTOXICITY; STRATEGY FOR EXAMINATION OF THE NEUROTOXIC POTENTIAL OF MEPHEDRONE; MEPHEDRONE DOES NOT DAMAGE DA NERVE ENDINGS
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MEPHEDRONE ENHANCES THE NEUROTOXICITY CAUSED BY METHAMPHETAMINE, AMPHETAMINE, AND MDMAMEPHEDRONE DOES NOT DAMAGE 5HT NERVE ENDINGS; DISCUSSION; APPLICATIONS TO OTHER ADDICTIONS AND SUBSTANCE MISUSE; DEFINITION OF TERMS; KEY FACTS OF MEPHEDRONE ABUSE; SUMMARY POINTS; REFERENCES; B - Molecular and Cellular Aspects; 4 - Cocaine and Brain-Derived Neurotrophic Factor; INTRODUCTION; BDNF, COCAINE, AND ANIMAL MODELS; BDNF, Cocaine, and the Mesolimbic Pathway; BDNF and Acute or Repeated Cocaine Exposure; BDNF GENETICS IN COCAINE ADDICTION; BDNF Gene Expression; BDNF Gene Polymorphisms
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CLINICAL STUDIES AND BDNFAPPLICATIONS TO OTHER ADDICTIONS AND SUBSTANCE MISUSE; DEFINITION OF TERMS; KEY FACTS OF COCAINE AND BDNF; SUMMARY POINTS; REFERENCES; 5 - On the Role of the Endocannabinoid System in Cocaine Addiction; INTRODUCTION; OVERVIEW OF THE ECBS; Endocannabinoids; Cannabinoid Receptors; Cannabinoid Receptors Ligands; Cannabinoid Enzyme Inhibitors; ECBS IN COCAINE ADDICTION; Cocaine and Marijuana Interactions in Polydrug Users; ECBS and Animal Models of Cocaine Addiction: Behavioral Studies; CB1R and Animal Models of Cocaine Addiction: Biochemical and Molecular Studies
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CONCLUSIONS
Additional Edition:
ISBN 0-12-800212-3
Language:
English
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