Umfang:
Online-Ressource (XXXII, 368 S., [2] Bl.)
ISBN:
0121822710
,
9780121822712
Serie:
Methods in enzymology 368
Inhalt:
Accurate molecular structures are vital for rational drug design and for structure-based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding. * Methodological methods in crystals * Methodological methods data analysis
Inhalt:
Accurate molecular structures are vital for rational drug design and for structure-based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding.* Methodological methods in crystals* Methodological methods data analysis
Anmerkung:
Description based upon print version of record
,
Cover; Table of Contents; Contributor to Volume 368; Preface; Volumes in Series; Section I: Reminiscences on Methods; Chapter 1. Transformations in Structural Biology: Personal View; Chapter 2. Origins; Chapter 3. Personal X-ray Reflections; Section II: Crystals; Chapter 4. Robotics for Automated Crystal Formation and Analysis; Chapter 5. Use of Limited Proteolysis to Identify Protein Domains Suitable for Structural Analysis; Chapter 6. Solvent Entropy Effects in the Formation of Protein Solid Phases
,
Chapter 7. Controlling Biomolecular Crystallization by Understanding the Distinct Effects of PEGs and Salts on SolubilityChapter 8. Counter-diffusion Methods for Macromolecular Crystallization; Chapter 9. Growth Sectors and Crystal Quality; Chapter 10. Molecular Mechanisms of Defect Formation; Chapter 11. Cryocooling of Macromolecular Crystals: Optimization Methods; Chapter 12. The Well-Tempered Protein Crystal:Annealing Macromolecular Crystals; Section III: Data; Chapter 13. What Can I Have As a Source of X-Ray Synchrotron Radiation? A Primer for Potential Users
,
Chapter 14. Protein Crystal Structure Analysis from High- Resolution X-Ray Powder-Diffraction DataChapter 15. Macromolecular Crystal Quality; Chapter 16. Protein Structures at Atomic Resolution; Author Index; Subject Index; Color Plates Section;
,
Literaturangaben
In:
Pt. C
Weitere Ausg.:
Erscheint auch als Druck-Ausgabe Macromolecular crystallography ; Pt. C Amsterdam [u.a.] : Elsevier, 2003 ISBN 0121822710
Sprache:
Englisch
Schlagwort(e):
Electronic books
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