UID:
almafu_9958132557302883
Umfang:
1 online resource (867 p.)
ISBN:
9786611011482
,
9781281011480
,
1281011487
,
9780080497198
,
0080497195
Serie:
Methods in enzymology, v. 381
Inhalt:
The ability of cells to sense and respond to changes in oxygenation underlies a multitude of developmental, physiological, and pathological processes. This volume provides a comprehensive compendium of experimental approaches to the study of oxygen sensing in 48 chapters that are written by leaders in their fields.
Anmerkung:
Description based upon print version of record.
,
Front Cover; Oxygen Sensing; Copyright Page; Table of Contents; Contributors to Volume 381; Preface; Volumes in Series; Section I: Lung and the Airways; Chapter 1. Assessment of Oxygen Sensing by Model Airway and Arterial Chemoreceptors; Chapter 2. Methods to Study Neuroepithelial Bodies as Airway Oxygen Sensors; Chapter 3. Role of Glutathione Redox State in Oxygen Sensing by Carotid Body Chemoreceptor Cells; Chapter 4. Determination of Signaling Pathways Responsible for Hypoxic Pulmonary Vasoconstriction: Use of the Small Vessel Myograph
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Chapter 5. Oxygen-Dependent Regulation of Pulmonary CirculationChapter 6. Detection of Oxygen Sensing During Intermittent Hypoxia; Chapter 7. Functional Analysis of the Role of Hypoxia-Inducible Factor 1 in the Pathogenesis of Hypoxic Pulmonary Hypertension; Section II: Cardiovascular and Blood; Chapter 8. Perceived Hyperoxia: Oxygen-Regulated Signal Transduction Pathways in the Heart; Chapter 9. Evaluation of Cytochrome P450-4A w-Hydroxylase and 20-Hydroxyeicosatetraenoic Acid as an O2 Sensing Mechanism in the Microcirculation
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Chapter 10. Assessment of Roles for Oxidant Mechanisms in Vascular Oxygen SensingChapter 11. Survival Surgery for Coronary Occlusion and Reoxygenation in a Rodent Model; Chapter 12. Measurement of In Vivo Oxidative Stress Regulated by the Rac1 GTPase; Chapter 13. Proteomic Analysis of the Mammalian Cell Nucleus; Chapter 14. Oxygen-Dependent Regulation of Erythropoiesis; Chapter 15. Physiologic Responses to Chronic Anemia in Fetal Sheep; Chapter 16. Hypoxia-Inducible Factor 1 a-Deficient Chimeric Mice as a Model to Study Abnormal B Lymphocyte Development and Autoimmunity
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Section III: Ion ChannelsChapter 17. Molecular Strategies for Studying Oxygen- Sensitive Kþ Channels; Chapter 18. Oxygen Sensing by Human Recombinant K+* Channels: Assessment of the Use of Stable Cell Lines; Chapter 19. Methods to Study Oxygen Sensing Sodium Channels; Chapter 20. Analysis of Oxygen-Sensitive Human Cardiac L-Type Ca2+ Channel a1C Subunit (hHT Isoform); Section IV: Tumor Biology; Chapter 21. Analysis of von Hippel-Lindau Tumor Suppressor as a Mediator of Cellular Oxygen Sensing; Chapter 22. Analysis of von Hippel-Lindau Hereditary Cancer Syndrome: Implications of Oxygen Sensing
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Chapter 23. Tumor Hypoxia and Malignant ProgressionSection V: Metabolism; Chapter 24. Oxygen-Dependent Regulation of Hepatic Glucose Metabolism; Chapter 25. Assessing Oxygen Sensitivity of the Multidrug Resistance (MDR) Gene; Chapter 26. Oxygen-Dependent Regulation of Adipogenesis; Section VI: Nervous System; Chapter 27. Methods to Detect Hypoxia-Induced Ischemic Tolerance in the Brain; Chapter 28. Proximal Middle Cerebral Artery Occlusion Surgery for the Study of Ischemia-Reoxygenation Injury in the Brain
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Chapter 29. Carotid Chemodenervation Approach to Study Oxygen Sensing in Brain Stem Catecholaminergic Cells
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English
Weitere Ausg.:
ISBN 9780121827854
Weitere Ausg.:
ISBN 0121827852
Sprache:
Englisch
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