Format:
Online-Ressource (XLVIII, 436 S.)
Edition:
Online-Ausg.
ISBN:
1281749354
,
9780123743091
,
9780080884356
,
9781281749352
Series Statement:
Nitric oxide / ed. by Lester Packer Pt. G
Content:
The Nobel Prize was awarded in Physiology or Medicine in 1998 to Louis J. Ignarro, Robert F. Furchgott and Ferid Murad for demonstrating the signaling properties of nitric oxide. Nitric Oxide (NO) is one of the few gaseous signaling molecules and is a key biological messenger that plays a role in many biological processes. NO research has led to new treatments for treating heart as well as lung diseases, shock and impotence. (Sildenafil, popularly known by the trade name Viagra, enhances signaling through nitric oxide pathways.) Scientists are currently testing whether NO can be used to stop the growth of cancerous tumors, since the gas can induce programmed cell death, apoptosis. This is another "must-have" volume packed with robust methods from authors around the globe. Researchers interested in the detailed biochemistry of nitric oxide and its synthesis will have this indispensable volume on their shelves. *Essential resource for every laboratory involved in NO-related work *Gathers tried and tested techniques from global labs which eliminates searching through many different sources and avoids pitfalls so the same mistakes are not made over and over. * Aids researchers in the design of medically important therapies for heart disease and cancer ...
Note:
Description based on print version record
,
Includes bibliographical references and indexes
,
Protein 3-nitrotyrosine in complex biological samples : quantification by high-pressure liquid chromatography/electrochemical detection and emergence of proteomic approaches for unbiased identification of modification sites / Tal Nuriel ... [et al.]Selective fluorogenic derivatization of 3-nitrotyrosine and 3,4-dihydroxyphenylalanine in peptides : a method designed for quantitative proteomic analysis / Victor S. Sharov ... [et al.] -- Nitroalkenes : synthesis, characterization and effects on macrophage activation / Ana María Ferreira ... [et al.] -- In-gel detection of S-nitrosated proteins using fluorescence methods / Nicholas J. Kettenhofen ... [et al.] -- The arachidonate-dependent survival signaling preventing toxicity in monocytes/macrophages exposed to peroxynitrite / Orazio Cantoni, Ilaria Tommasini and Liana Cerioni -- Practical approaches to investigate redox regulation of heat shock protein expression and intracellular glutathione redox state / Vittorio Calabrese ... [et al.] -- Monitoring oxidative stress in vascular endothelial cells in response to fluid shear stress : from biochemical analyses to micro- and nanotechnologies / Mahsa Rouhanizadeh ... [et al.] -- Determination of S-nitrosothiols in biological and clinical samples using electron paramagnetic resonance spectrometry with spin trapping / Paul G. Winyard ... [et al.] -- Novel method for measuring S-nitrosothiols using hydrogen sulfide / Xinjun Teng ... [et al.] -- Kinetic studies on peroxynitrite reduction by peroxiredoxins / Madia Trujillo, Gerardo Ferrer-Sueta and Rafael Radi -- Nitrocytochrome c : synthesis, purification and functional studies / José M. Souza ... [et al.] -- Tyrosine nitration, dimerization and hydroxylation by peroxynitrite in membranes as studied by the hydrophobic probe N-t-BOC-l-tyrosine tert-Byl Ester / Silvina Bartesaghi ... [et al.] -- Assessment of superoxide production and NADPH oxidase activity by HPLC analysis of dihydroethidium oxidation products / Francisco R.M. Laurindo, Denise C. Fernandes and Célio X.C. Santos -- Methods to measure the reactivity of peroxynitrite-derived oxidants toward reduced fluoresceins and rhodamines / Peter Wardman -- Detection and characterization of peroxynitrite-induced modifications of tyrosine, tryptophan and methionine residues by tandem mass spectrometry / Igor Rebrin ... [et al.] -- Reductive gas-phase chemiluminescence and flow injection analysis for measurement of the nitric oxide pool in biological matrices / Ulrike Hendgen-Cotta ... [et al.] -- Detection and measurement for the modification and inactivation of caspase by nitrosative stress In Vitro and In Vivo / Hee-Jun Na ... [et al.] -- Interactive relations between nitric oxide (NO) and carbon monoxide (CO) : heme oxygenase-1/CO pathway is a key modulator in NO-mediated antiapoptosis and anti-inflammation / Hun-Taeg Chung -- Detection and characterization of In Vivo nitration and oxidation of tryptophan residues in proteins / Catherine Bregere, Igor Rebrin and Rajindar S. Sohal -- In Vivo real-time measurement of nitric oxide in anesthetized rat brain / Rui M. Barbosa ... [et al.] -- Nitric oxide and cardiobiology-methods for intact hearts and isolated myocytes / Joshua M. Hare, Farideh Beigi and Konstantinos Tziomalos -- Microscopic technique for the detection of nitric oxide-dependent angiogenesis in an animal model / Seung Namkoong ... [et al.].
Additional Edition:
Erscheint auch als Druck-Ausgabe Nitric oxide ; Pt. G: Oxidative and nitrosative stress in redox regulation of cell signaling Amsterdam [u.a.] : Elsevier, Acad. Press, 2008 ISBN 9780123743091
Language:
English
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