Umfang:
Online-Ressource (563 p)
Ausgabe:
Online-Ausg.
ISBN:
9780124080881
,
0124081088
Inhalt:
Development of Auditory and Vestibular Systems fourth edition presents a global and synthetic view of the main aspects of the development of the stato-acoustic system. Unique to this volume is the joint discussion of two sensory systems that, although close at the embryological stage, present divergences during development and later reveal conspicuous functional differences at the adult stage. This work covers the development of auditory receptors up to the central auditory system from several animal models, including humans. Coverage of the vestibular system, spanning amphibians to effects o
Anmerkung:
Description based upon print version of record
,
Front Cover; Development of Auditory and Vestibular Systems; Copyright; Contents; Contributors; Chapter 1 - Early Development of the Vertebrate Inner Ear; SUMMARY; 1. THE ADULT INNER EAR; 2. DEVELOPMENT OF THE INNER EAR; References; Chapter 2 - Development of the Auditory Organ (Johnston's Organ) in Drosophila; OUTLINE; SUMMARY; 1. JOHNSTON'S ORGAN AS A SPECIALIZED CHORDOTONAL ORGAN; 2. STRUCTURE AND FUNCTION OF JOHNSTON'S ORGAN; 3. DEVELOPMENT OF JOHNSTON'S ORGAN; 4. GENETIC CONTROL OF EARLY PATTERNING; 5. REGULATION OF ATONAL AND SENSE ORGAN PRECURSOR SPECIFICATION IN JO DEVELOPMENT
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6. GENERATING SCOLOPIDIA: DIVISION OF THE SENSE ORGAN PRECURSORS7. CHORDOTONAL NEURON DIFFERENTIATION IN JO DEVELOPMENT; 8. STRUCTURE OF JO NEURONS; 9. GENE ACTIVATION DURING JO NEURON DIFFERENTIATION; 10. TRANSCRIPTIONAL REGULATION OF CILIOGENESIS AND ASSEMBLY OF THE MECHANOSENSORY APPARATUS; 11. DEVELOPMENTAL EMERGENCE OF MECHANOSENSORY SPECIALIZATION; 12. HOW MUCH OF THE DEVELOPMENTAL REGULATORY NETWORK IS CONSERVED IN VERTEBRATE HAIR CELLS?; 13. SUPPORT CELL DIFFERENTIATION; 14. JO SENSORY SUBSPECIALIZATIONS MAP TO DISTINCT SUBGROUPS OF JO NEURONS
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15. THE DEVELOPMENT OF JO NEURONAL SUBGROUPS16. SOUND DETECTION AND CHORDOTONAL DIVERSITY IN THE DROSOPHILA LARVA; 17. CONCLUSIONS; References; Chapter 3 - Zebrafish Inner Ear Development and Function; SUMMARY; 1. INTRODUCTION; 2. DEVELOPMENT OF THE ZEBRAFISH INNER EAR; 3. ZEBRAFISH HEARING AND VESTIBULAR FUNCTION; 4. DISEASE MODELS; 5. NEW TECHNOLOGIES; 6. CONCLUSIONS AND FUTURE DIRECTIONS; References; Chapter 4 - Human Gene Discovery for Understanding Development of the Inner Ear and Hearing Loss; 1. INTRODUCTION - THE GENETICS OF HEREDITARY HEARING LOSS; 2. IDENTIFICATION OF DEAFNESS GENES
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3. MECHANISMS OF HEARING - LESSONS FROM MICE4. DEVELOPMENT OF THE INNER EAR; 5. THE HAIR BUNDLE AND STEREOCILIA; 6. JUNCTIONS BETWEEN CELLS: GAP AND TIGHT JUNCTIONS; 7. PLANAR CELL POLARITY OF THE HAIR BUNDLE; 8. GENE EXPRESSION AND REGULATION; 9. SUMMARY; References; Chapter 5 - Planar Cell Polarity in the Cochlea; 1. INTRODUCTION; 2. PLANAR CELL POLARITY IN THE INNER EAR; 3. PLANAR CELL POLARITY REGULATION IN THE COCHLEA; 4. CONCLUSIONS AND PERSPECTIVES; References; Chapter 6 - Functional Development of Hair Cells in the Mammalian Inner Ear; 1. INTRODUCTION; 2. MAMMALIAN AUDITORY SYSTEM
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3. MAMMALIAN VESTIBULAR SYSTEM4. CONCLUSIONS AND REMARKS; References; Chapter 7 - Neuronal Circuitries During Inner Ear Development; 1. INTRODUCTION; 2. DEVELOPMENT OF THE AFFERENT INNERVATION PATTERN; 3. DEVELOPMENT OF THE EFFERENT INNERVATION PATTERN; 4. CONCLUSIONS; References; Chapter 8 - Recapitulating Inner Ear Development with Pluripotent Stem Cells: Biology and Translation; 1. INTRODUCTION; 2. WHY STEM CELLS?; 3. PROGRESS TOWARDS RECONSTITUTION OF INNER EAR DEVELOPMENT IN VITRO; 4. PROSPECTS FOR CLINICAL TRANSLATION; 5. CONCLUSION; References
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Chapter 9 - Development of Mammalian Primary Sound Localization Circuits
Weitere Ausg.:
ISBN |p|
Weitere Ausg.:
ISBN 9780124081086
Weitere Ausg.:
ISBN 012408088X
Weitere Ausg.:
Erscheint auch als Druck-Ausgabe Development of auditory and vestibular systems
Weitere Ausg.:
Druckausg. Development of auditory and vestibular systems Amsterdam [u.a.] : Academic Press, 2014 ISBN 9780124080881
Sprache:
Englisch
Fachgebiete:
Biologie
Schlagwort(e):
Electronic books
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