Kooperativer Bibliotheksverbund

UID:

Umfang: 1 online resource (280 pages)

Ausgabe: First edition.

ISBN: 9780128148013 , 0128148012 , 9780128148006 , 0128148004

Anmerkung: Front Cover -- Microbiota Brain Axis -- Microbiota Brain Axis -- Copyright -- Contents -- About the authors -- Foreword -- 1 - The gut-brain axis -- References -- 2 - What is a healthy microbiome? -- Introduction -- Microbiota composition and function in healthy individuals -- Microbiota diversity across body sites in healthy individuals -- Interindividual differences in bacterial taxa in healthy individuals -- Sex influences microbiota composition and function -- Age influences microbiota composition and function -- Diet influences microbiota composition and function -- Key taxa in the healthy microbiome -- Faecalibacterium prausnitzii -- Akkermansia muciniphila -- Bacteroides -- Prevotella -- Future directions -- References -- 3 - Gene-environment factors influence microbiota composition, diversity, and function -- Introduction -- Animal models -- Human studies -- Future directions -- References -- 4 - Microbiota to brain communication -- Introduction -- The vagus nerve in microbiota to brain communication -- The enteric nervous system in microbiota to brain communication -- The immune system in microbiota to brain communication -- Neuroendocrine signaling in microbiota to brain communication -- Microbial metabolites in microbiota to brain communication -- Microbial regulation of tryptophan metabolism in microbiota to brain communication -- Microbial microvesicles in microbiota to brain communication -- Conclusions, perspectives, and future directions -- References -- 5 - Microbiota influence behavior-Work in animal models -- Overview -- Behavior in germ-free mice -- Antibiotic-related changes in microbiota influence behavior -- The impact of stress on microbiota and behavior -- The impact of diet on microbiota and behavior -- Fecal matter transplantation alters behavior in recipient -- Future directions -- References. , 6 - Microbiota influence brain systems-Work in animal models -- Introduction -- Neuroimmune signaling -- Neurotransmission -- Neural plasticity -- Future directions -- References -- 7 - Microbiota in neurodevelopmental disorders -- Introduction -- Microbiota to brain communication in neurodevelopment -- Microbiota during pregnancy -- Stress and the postnatal microbiota -- C-section -- Preterm -- Antibiotics -- Mode of feeding -- General -- Microbiota in neurodevelopmental disorders -- Conclusions, perspectives, and future directions -- References -- 8 - Microbiota in psychiatry -- Introduction -- Microbes and mood in healthy people -- Microbes in mood and anxiety disorders -- Major depressive disorder -- Bipolar disorder -- Anxiety disorder -- Schizophrenia -- Future directions -- References -- 9 - Microbiota-brain interactions in aging and neurodegeneration -- Introduction -- The aging gut microbiome: focus on health -- Unhealthy aging and the gut microbiome -- Aging and the gut-brain axis -- Microbiome and Parkinson's disease -- Microbiome and Alzheimer's disease -- Other neurodegenerative disorders: ALS/MS/Huntington's -- Microbiome and aging: longevity in model organisms -- Microbiome and aging: turning back the clock in preclinical models -- Conclusions, perspectives, and future directions -- References -- 10 - Pharmacological treatments and the microbiome-Antibiotics and nonantibiotic drugs -- Introduction -- Antibiotics impact the microbiome and the microbiota-brain axis -- Exposure to antibiotics early in life-Animal studies -- Exposure to antibiotics early in life-Clinical studies -- Exposure in adolescence and adulthood -- The impact of nonantibiotic drugs on microbiota -- Future directions -- References -- 11 - Microbial-related treatments -- Introduction -- Probiotics -- Prebiotics -- Synbiotics -- Postbiotics -- Fermented foods and diet. , Fecal microbiota transplantation -- Antibiotics -- Conclusions, perspectives, and future directions -- References -- 12 - Microbiota-related biomarkers for precision medicine and drug discovery -- Introduction -- Translational science -- Microbiome biomarkers for precision health -- Where to next? -- References -- Abbreviations -- Index -- Back Cover.

Sprache: Englisch

UID:

Umfang: 1 online resource (280 pages)

Ausgabe: 1st ed.

ISBN: 0-12-814801-2 , 0-12-814800-4

Anmerkung: Front Cover -- Microbiota Brain Axis -- Microbiota Brain Axis -- Copyright -- Contents -- About the authors -- Foreword -- 1 - The gut-brain axis -- References -- 2 - What is a healthy microbiome? -- Introduction -- Microbiota composition and function in healthy individuals -- Microbiota diversity across body sites in healthy individuals -- Interindividual differences in bacterial taxa in healthy individuals -- Sex influences microbiota composition and function -- Age influences microbiota composition and function -- Diet influences microbiota composition and function -- Key taxa in the healthy microbiome -- Faecalibacterium prausnitzii -- Akkermansia muciniphila -- Bacteroides -- Prevotella -- Future directions -- References -- 3 - Gene-environment factors influence microbiota composition, diversity, and function -- Introduction -- Animal models -- Human studies -- Future directions -- References -- 4 - Microbiota to brain communication -- Introduction -- The vagus nerve in microbiota to brain communication -- The enteric nervous system in microbiota to brain communication -- The immune system in microbiota to brain communication -- Neuroendocrine signaling in microbiota to brain communication -- Microbial metabolites in microbiota to brain communication -- Microbial regulation of tryptophan metabolism in microbiota to brain communication -- Microbial microvesicles in microbiota to brain communication -- Conclusions, perspectives, and future directions -- References -- 5 - Microbiota influence behavior-Work in animal models -- Overview -- Behavior in germ-free mice -- Antibiotic-related changes in microbiota influence behavior -- The impact of stress on microbiota and behavior -- The impact of diet on microbiota and behavior -- Fecal matter transplantation alters behavior in recipient -- Future directions -- References. , 6 - Microbiota influence brain systems-Work in animal models -- Introduction -- Neuroimmune signaling -- Neurotransmission -- Neural plasticity -- Future directions -- References -- 7 - Microbiota in neurodevelopmental disorders -- Introduction -- Microbiota to brain communication in neurodevelopment -- Microbiota during pregnancy -- Stress and the postnatal microbiota -- C-section -- Preterm -- Antibiotics -- Mode of feeding -- General -- Microbiota in neurodevelopmental disorders -- Conclusions, perspectives, and future directions -- References -- 8 - Microbiota in psychiatry -- Introduction -- Microbes and mood in healthy people -- Microbes in mood and anxiety disorders -- Major depressive disorder -- Bipolar disorder -- Anxiety disorder -- Schizophrenia -- Future directions -- References -- 9 - Microbiota-brain interactions in aging and neurodegeneration -- Introduction -- The aging gut microbiome: focus on health -- Unhealthy aging and the gut microbiome -- Aging and the gut-brain axis -- Microbiome and Parkinson's disease -- Microbiome and Alzheimer's disease -- Other neurodegenerative disorders: ALS/MS/Huntington's -- Microbiome and aging: longevity in model organisms -- Microbiome and aging: turning back the clock in preclinical models -- Conclusions, perspectives, and future directions -- References -- 10 - Pharmacological treatments and the microbiome-Antibiotics and nonantibiotic drugs -- Introduction -- Antibiotics impact the microbiome and the microbiota-brain axis -- Exposure to antibiotics early in life-Animal studies -- Exposure to antibiotics early in life-Clinical studies -- Exposure in adolescence and adulthood -- The impact of nonantibiotic drugs on microbiota -- Future directions -- References -- 11 - Microbial-related treatments -- Introduction -- Probiotics -- Prebiotics -- Synbiotics -- Postbiotics -- Fermented foods and diet. , Fecal microbiota transplantation -- Antibiotics -- Conclusions, perspectives, and future directions -- References -- 12 - Microbiota-related biomarkers for precision medicine and drug discovery -- Introduction -- Translational science -- Microbiome biomarkers for precision health -- Where to next? -- References -- Abbreviations -- Index -- Back Cover.

Sprache: Englisch