UID:
almahu_9949984647702882
Umfang:
1 online resource (xiv, 665 pages) :
,
illustrations
ISBN:
0-323-90701-6
,
9780323907019
,
0323907016
Inhalt:
Medicinal Chemistry of Chemotherapeutic Agents: A Comprehensive Resource of Anti-infective and Anti-cancer Drugs focuses on the basics and fundamentals of chemistry involved in chemotherapeutic agents. Each chapter comprises distinct chemical classifications that include structure and IUPAC nomenclature, synthetic schemes and routes for each drug, mechanism of the drug action, metabolic pathway and structure-activity relationship (SAR) studies. The book covers current research focused on drug resistance and methods to overcome it, the development of newer drugs belonging to each category of the chemotherapeutic agents, molecules currently under clinical trials, and newly approved drugs, if any. This book will be a valuable resource for academics and researchers, helping them to understand the fundamentals of the medicinal chemistry of the chemotherapeutic agents. Includes current research focused on drug resistance and methods to overcome problems Outlines synthetic schemes and metabolic pathways of chemotherapeutic agents Discusses molecules under clinical trials and newly approved drugs.
Anmerkung:
1. Introduction to Chemotherapy: General and Clinical Considerations Section A. ANTIMICROBIAL AGENTS Unit I Antibacterial Agents -- 2. Sulfonamides, Quinolones, Antiseptics and Disinfectants Unit II Antibacterial Antibiotics -- 3. Beta-Lactam Antibiotics: Penicillins, Cephalosporins, Monobactams, Carbapenems and Beta-lactamase Inhibitors -- 4. Tetracyclines and Chloramphenicol -- 5. Aminoglycoside Antibiotics -- 6. Macrolide, Lincosamide, Glycopeptide and Other Antibacterial Antibiotics Unit III Antimycobacterial Agents -- 7. Antitubercular Drugs -- 8. Antileprotic Drugs Unit IV Antifungal Agents -- 9. Topical and Systemic Antifungal Drugs Unit V Antiviral Agents -- 10. Antiviral Drugs and Vaccines Unit VI Antiprotozoal Agents -- 11. Antimalarial Drugs -- 12. Antiamoebic Drugs -- 13. Drugs for Giardiasis, Trichomoniasis and Leishmaniasis UNIT VII Anthelmintics -- 14. Vermifuge and Vermicide Drugs Section B ANTINEOPLASTIC AGENTS -- 15. Synthetic Cytotoxic Drugs as Cancer Chemotherapeutic Agents -- 16. Naturally Occurring Anticancer Cytotoxic Drugs -- 17. Hormones and Antihormones in Cancer Chemotherapy -- 18. Biologicals and Small Molecules as Target Specific Cancer Chemotherapeutic Agents.
Weitere Ausg.:
Print version: Acharya, Pratap Chandra Medicinal Chemistry of Chemotherapeutic Agents San Diego : Elsevier Science & Technology,c2023 ISBN 9780323905756
Sprache:
Englisch
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