Format:
Online-Ressource (digital)
ISBN:
9780387096933
Series Statement:
SpringerLink
Content:
Glycerophospholipid and sphingolipid-derived lipid mediators facilitate the transfer of messages not only from one cell to another but also from one subcellular organelle to another. These molecules are not only components of neural membranes but also storage depots for lipid mediators. Information on the generation and involvement of lipid mediators in neurological disorders is scattered throughout the literature in the form of original papers and reviews. This book will provide readers with a comprehensive description of glycerophospholipid, sphingolipid and cholesterol-derived lipid mediators and their involvement in neurological disorders.
Note:
Includes bibliographical references and index
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Hot Topics in Neural Membrane Lipidology; Preface; Acknowledgments; Contents; List of Abbreviations; About the Author; Neural Membranes: A Pandora's Box of Lipid Mediators; 1.1 Lipid Composition of Neural Membranes; 1.2 Glycerophospholipids and Their Metabolism in Brain; 1.3 Arachidonic Acid and Its Enzymically Derived Oxidation Products; 1.3.1 Arachidonic Acid and Lyso-glycerophospholipids; 1.3.2 Lysophosphatidylcholine (lyso-PtdCho); 1.3.3 Eicosanoids; 1.3.4 Lipoxins; 1.4 Non-enzymic Oxidation of Arachidonic Acid; 1.4.1 4-Hydroxynonenal (4-HNE); 1.4.2 Isoprostanes; 1.4.3 Isoketals
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1.4.4 Isofurans1.5 Enzymic and Non-enzymic Oxidation of DHA; 1.5.1 Enzymically Derived Lipid Mediators of DHA; 1.5.2 Resolvins; 1.5.3 Protectins and Neuroprotectins; 1.6 Non-enzymic Oxidation of Docosahexaenoic Acid; 1.6.1 4-Hydroxyhexenal; 1.6.2 Neuroprostanes; 1.6.3 Neuroketals (NK); 1.7 Sphingolipid Metabolism in Brain; 1.7.1 Ceramide and Ceramide 1-Phosphate; 1.7.2 Sphingosine and Sphingosine 1-Phosphate; 1.8 Cholesterol Metabolism in Brain; 1.9 Association of Lipid Mediators with Neurological Disorders; 1.10 Conclusion; References
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Interplay Among Glycerophospholipid, Sphingolipid, and Cholesterol-Derived Lipid Mediators in Brain: A Matter of Life and Death2.1 Introduction; 2.2 Generation of Glycerophospholipid-Derived Lipid Mediators; 2.3 Enzymically-Derived AA Metabolites and Neuroinflammation; 2.4 Platelet-Activating Factor in Brain; 2.5 Metabolism of Sphingolipid-Derived Lipid Mediators in Brain; 2.6 Neurochemical Effects and Roles of Ceramides; 2.7 Generation of Cholesterol-Derived Metabolites in Brain; 2.8 Interactions Among Phospholipid, Sphingolipid, and Cholesterol-Derived Lipid Mediators
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2.8.1 Interactions Between Glycerophospholipid and Sphingolipid Metabolism2.8.2 Interactions Between Glycerophospholipid and Sphingolipid-Derived Lipid Mediators; 2.8.3 Interactions Between Glycerophospholipid and Cholesterol-Derived Lipid Mediators; 2.8.4 Interactions Between Sphingolipid and Cholesterol-Derived Lipid Mediators; 2.9 Conclusion; References; Janus Face of Phospholipase A2: Role of Phospholipase A2 in Neural Cell Survival and Death; 3.1 Introduction; 3.2 Multiplicity of PLA2 in Brain Tissue; 3.2.1 Cytosolic Phospholipase A2 (cPLA2)
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3.2.2 Calcium Independent Phospholipase A2(iPLA2)3.2.3 Secretory Phospholipase A2 (sPLA2); 3.2.4 Plasmalogen Selective Phospholipase A2 (PlsEtn-PLA2); 3.3 Role of Multiple Forms of PLA2 in Brain; 3.3.1 Multiple Forms of PLA2 and Neurotransmitter Release; 3.3.2 Multiple Forms of PLA2 in Long-Term Potentiation and Long-Term Depression; 3.3.3 Multiple Forms of PLA2 in Membrane Repair; 3.3.4 Multiple Forms of PLA2 in Modulation of Neurite Outgrowth and Regeneration; 3.3.5 Multiple Forms of PLA2 in Tubule Formation and Membrane Trafficking; 3.3.6 Multiple Forms of PLA2 in the Cell Cycle
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3.3.7 Multiple Forms of PLA2 in Neuroinflammation
Additional Edition:
ISBN 9780387096926
Additional Edition:
Buchausg. u.d.T. The physics of selenium and tellurium Berlin : Springer, 1979 ISBN 3540096922
Additional Edition:
ISBN 0387096922
Language:
English
Subjects:
Physics
Keywords:
Tellur
;
Physik
;
Selen
;
Physik
;
Tellur
;
Physikalische Eigenschaft
;
Selen
;
Physikalische Eigenschaft
;
Tellur
;
Physik
;
Selen
;
Physik
;
Tellur
;
Physikalische Eigenschaft
;
Selen
;
Physikalische Eigenschaft
;
Konferenzschrift
;
Konferenzschrift
DOI:
10.1007/978-0-387-09693-3
URL:
Volltext
(lizenzpflichtig)
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