Umfang:
Online-Ressource (digital)
ISBN:
9780387708300
Serie:
SpringerLink
Inhalt:
A superb source of reference reviews as well as a concise overview of the functional cross-talk between neurons and glial cells, this book also focuses on microglia and inflammation in the aging brain and in neurological disorders. The scientific spectrum covered by this book is of key interest, and is recognized by the scientific community as a major competitive area with critical implications for human health.
Inhalt:
"Interactions Between Neurons and Glia in Aging and Disease is a source of ""reference reviews"" and ""concise overviews"" of the functional cross-talk between neurons and glial cells, with a focus on microglia and inflammation in the aging brain and in neurological disorders. The scientific area covered by this book may be considered of key interest, and it is recognized, by the scientific community, as a major competitive area with critical implications for human health. This book is organized in three main sections that are expected to guide the readers from the basic functional cross-talk between neuron and glia to brain pathology. The specific proposed sections are: 1) Neuroimmunity and Neuroinflammation, 2) Signalling and inflammation in aging, 3) Neurodegeneration and inflammation in age related diseases."
Anmerkung:
Includes bibliographical references and index
,
CONTENTS; Section 1 Neuroimmunity and neuroinflammation; Chapter 1. Inflammation and Neuronal Susceptibility to Excitotoxic Cell Death; Chapter 2. Microglial Cell Population Expansion Following Acute Neural Injury; Chapter 3. Opposite Modulation of Peripheral Inflammation and Neuroinflammationby Adenosine A 2A Receptors; Chapter 4. Subventricular Zone Cells as a Tool for Brain Repair; Section 2 Signaling and inflammation in aging; Chapter 5. Neuron-Glia Interaction in Homeostasis of the NeurotransmittersGlutamate and GABA
,
Chapter 6. The Impact of an Imbalance Between Proinflammatory andAnti-inflammatory Influences on Synaptic Function in the Aged BrainChapter 7. Neurotrophin Signaling and Cell Survival; Chapter 8. GDNF: a Key Player in Neuron-Glia Crosstalk and Survivalof Nigrostriatal Dopaminergic Neurons; Chapter 9. Molecular Pathways of Mitochondrial Dysfunction in Neurodegeneration:the Paradigms of Parkinson's and Huntington's Diseases; Chapter 10. Zinc Homeostasis and Brain Injury; Chapter 11. Aging and Cognitive Decline: Neuroprotective Strategies
,
Section 3 Neurodegeneration and inflammation in age related diseasesChapter 12. Inflammation and Apoptotic Pathways in the Peripheral Nervous SystemRelated to Protein Misfolding; Chapter 13. Neuroinflammation and Excitotoxicity in Neurobiology of HIV-1 Infection and AIDS: Targets for Neuroprotection; Chapter 14. Neuroinflammation and Mitochondrial Dysfunction in Alzheimer'sand Prion's Diseases; Chapter 15. Metal Ions and Alzheimer's Disease; Chapter 16. Epilepsy, Brain Injury and Cell Death; Chapter 17. Glia and Hippocampal Neurogenesis in the Normal, Agedand Epileptic Brain
,
Chapter 18. Polyglutamine Expansion Diseases - the Caseof Machado-Joseph DiseaseChapter 19. Remyelination of the Central Nervous System; Chapter 20. Adult Neurogenesis in Neurodegenerative Diseases; Chapter 21. ATP Receptors in the Pain Signaling: Glial Contributionin Neuropathic Pain; Chapter 22. Diabetic Retinopathy, Inflammation, and Proteasome; Chapter 23. Rejuvenating Neurons and Glia with Microbial Enzymes; Abbreviations; Index
Weitere Ausg.:
ISBN 9780387708294
Weitere Ausg.:
Buchausg. u.d.T. ISBN 9780387708294
Sprache:
Englisch
Schlagwort(e):
Nervensystem
;
Alter
;
Krankheit
DOI:
10.1007/978-0-387-70830-0
URL:
Volltext
(lizenzpflichtig)
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