Format:
Online-Ressource (xxi, 570 p., [8] p. of col. plates)
,
ill. (some col.)
,
25 cm
Edition:
2nd ed
Edition:
Online-Ausg. Palo Alto, Calif ebrary 2009 Electronic reproduction; Available via World Wide Web
ISBN:
9780470026700
,
9780470512951
,
0470512962
,
9780470512968
Content:
This is the second edition of a unique book in the field of in vivo NMR covering in detail the technical and biophysical aspects of the technique. The contents of the book are appropriate to both beginners and experienced users of in vivo NMR spectroscopy. The new edition is focussed on bringing the reader practical insights and advice, but is also geared towards use as a study aid and in NMR courses. Recent advances in NMR spectroscopy, like high field NMR, hyperpolarized NMR and new localization and editing techniques have been included. An extensive and updated treatment of radiofrequency p
Content:
This is the second edition of a unique book in the field of in vivo NMR covering in detail the technical and biophysical aspects of the technique. The contents of the book are appropriate to both beginners and experienced users of in vivo NMR spectroscopy. The new edition is focussed on bringing the reader practical insights and advice, but is also geared towards use as a study aid and in NMR courses. Recent advances in NMR spectroscopy, like high field NMR, hyperpolarized NMR and new localization and editing techniques have been included. An extensive and updated treatment of radiofrequency p
Note:
Includes bibliographical references and index
,
In Vivo NMR Spectroscopy - 2nd Edition; Contents; Preface; List of Abbreviations and Symbols; 1 Basic Principles; 1.1 Introduction; 1.2 Classical Description; 1.3 Quantum Mechanical Description; 1.4 Macroscopic Magnetization; 1.5 Excitation; 1.6 Bloch Equations; 1.7 Fourier Transform NMR; 1.8 Chemical Shift; 1.9 Digital Fourier Transform NMR; 1.9.1 Multi-scan Principle; 1.9.2 Time-domain Filtering; 1.9.3 Analog-To-Digital Conversion; 1.9.4 Zero Filling; 1.10 Spin-spin Coupling; 1.10.1 Spectral Characteristics; 1.11 T1 Relaxation; 1.12 T2 Relaxation and Spin-echoes; 1.13 Exercises; References
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2 In Vivo NMR Spectroscopy - Static Aspects2.1 Introduction; 2.2 Proton NMR Spectroscopy; 2.2.1 Acetate (Ace); 2.2.2 N-Acetyl Aspartate (NAA); 2.2.3 N-Acetyl Aspartyl Glutamate (NAAG); 2.2.4 Adenosine Triphosphate (ATP); 2.2.5 Alanine (Ala); 2.2.6 -Aminobutyric Acid (GABA); 2.2.7 Ascorbic Acid (Asc); 2.2.8 Aspartate (Asp); 2.2.9 Choline-containing Compounds (tCho); 2.2.10 Creatine (Cr) and Phosphocreatine (PCr); 2.2.11 Ethanolamine and Phosphorylethanolamine (PE); 2.2.12 Glucose (Glc); 2.2.13 Glutamate (Glu); 2.2.14 Glutamine (Gln); 2.2.15 Glutathione (GSH); 2.2.16 Glycerol; 2.2.17 Glycine
,
2.2.18 Glycogen2.2.19 Histamine; 2.2.20 Histidine; 2.2.21 Homocarnosine; 2.2.22 -Hydroxybutyrate (BHB); 2.2.23 Myo-Inositol (mI) and scyllo-Inositol (sI); 2.2.24 Lactate (Lac); 2.2.25 Macromolecules; 2.2.26 Phenylalanine; 2.2.27 Pyruvate; 2.2.28 Serine; 2.2.29 Succinate; 2.2.30 Taurine (Tau); 2.2.31 Threonine (Thr); 2.2.32 Tryptophan (Trp); 2.2.33 Tyrosine (Tyr); 2.2.34 Valine (Val); 2.2.35 Water; 2.2.36 Intra- and Extramyocellular Lipids (IMCL and EMCL); 2.2.37 Deoxymyoglobin (DMb); 2.2.38 Citric Acid; 2.2.39 Carnosine; 2.3 Phosphorus-31 NMR Spectroscopy; 2.3.1 Identification of Resonances
,
2.3.2 Intracellular pH2.4 Carbon-13 NMR Spectroscopy; 2.4.1 Identification of Resonances; 2.5 Sodium-23 and Potassium-39 NMR Spectroscopy; 2.6 Fluorine-19 NMR Spectroscopy; 2.6.1 Identification of Resonances; 2.6.2 Fluorinated Drugs, Anaesthetics, and Fluorodeoxyglucose Metabolism; 2.6.3 Fluorinated Probes; 2.7 Exercises; References; 3 In Vivo NMR Spectroscopy - Dynamic Aspects; 3.1 Introduction; 3.2 Relaxation; 3.2.1 General Principles of Dipolar Relaxation; 3.2.2 Nuclear Overhauser Effect; 3.2.3 Alternative Relaxation Mechanisms; 3.2.4 In Vivo Relaxation; 3.3 Magnetization Transfer
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3.3.1 Creatine Kinase3.3.2 Inversion Transfer; 3.3.3 Saturation Transfer; 3.3.4 ATpases; 3.3.5 Fast Magnetization Transfer Methods; 3.3.6 Off-resonance Magnetization Transfer; 3.3.7 Chemical Exchange Dependent Saturation Transfer; 3.4 Diffusion; 3.4.1 Principles of Diffusion; 3.4.2 Diffusion and NMR; 3.4.3 Anisotropic Diffusion; 3.4.4 Restricted Diffusion; 3.5 Dynamic Carbon-13 NMR Spectroscopy; 3.5.1 General Set-up; 3.5.2 Metabolic Modeling; 3.5.3 Substrates; 3.5.4 Applications; 3.6 Hyperpolarization; 3.6.1 "Brute Force" Hyperpolarization; 3.6.2 Optical Pumping of Noble Gases
,
3.6.3 Para-hydrogen-induced Polarization (PHIP)
,
Electronic reproduction; Available via World Wide Web
Additional Edition:
ISBN 0470512954
Additional Edition:
ISBN 9780470512951
Additional Edition:
ISBN 0470026707
Additional Edition:
ISBN 9780470026700
Additional Edition:
Erscheint auch als Druck-Ausgabe In Vivo NMR Spectroscopy Principles and Techniques
Language:
English
Subjects:
Chemistry/Pharmacy
Keywords:
NMR-Spektroskopie
DOI:
10.1002/9780470512968
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