UID:
almafu_9959327679102883
Umfang:
1 online resource (xvi, 347 pages, 16 unnumbered pages of plates) :
,
illustrations (some color)
ISBN:
9780470423929
,
0470423927
,
9780470423936
,
0470423935
Inhalt:
As research progresses and information continues to proliferate in the field of molecular design for therapeutic use, there is a need for a reference that brings current theory and proven practice together in a how-to volume. This reference guides scientists new to the field on how to design small molecules that interact with critical protein targets. The chapters condense useful material into a manageable format which is carefully organized and presented. It offers an essential resource for a variety of chemists in academia, and the biotech and pharmaceutical industries, as well as profession.
Anmerkung:
Drug discoveries by gene family / Karen E. Lackey -- G-protein coupled receptors / Stephen L. Garland and Tom D. Heightman -- Ion channels gene family : strategies for discovering ion channel drugs / Maria L. Garcia and Gregory J. Kaczorowski -- Integrins / David D. Miller -- Strategies for discovering kinase drugs / Jerry L. Adams [and others] -- Protease-directed drug discovery / Richard Sedrani, Ulrich Hommel, and Jor̈g Eder -- Small-molecule inhibitors of protein-protein interactions : challenges and prospects / Adrian Whitty -- Transporters / Anne Hersey, Frank E. Blaney, and Sandeep Modi -- Nuclear receptor drug discovery / Hiroyuki Kagechika and Aya Tanatani -- Summary and comparison of molecules designed to modulate druggable targets in the major gene families / Karen E. Lackey.
Weitere Ausg.:
Print version: Gene family targeted molecular design. Hoboken, N.J. : John Wiley & Sons, ©2009 ISBN 9780470412893
Weitere Ausg.:
ISBN 0470412895
Sprache:
Englisch
Schlagwort(e):
Electronic books.
;
Electronic books.
;
Electronic books.
DOI:
10.1002/9780470423936
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/9780470423936
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/9780470423936
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/9780470423936
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