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  • 1
    Online-Ressource
    Online-Ressource
    Hoboken :Wiley,
    UID:
    almafu_9959328494702883
    Umfang: 1 online resource (xxviii, 372 pages) : , illustrations
    ISBN: 9780470918562 , 047091856X
    Anmerkung: Tools for Biomarker Discovery. Biomarkers: An Evolutionary Perspective / Michael A Ferguson, Vishal S Vaidya -- Genomics / Weida Tong, Donna L Mendrick -- Proteomics for Biomarker Discovery / Timothy D Veenstra -- Metabolic Profiling for Biomarker Discovery / Hector C Keun -- The Bittersweet Promise of Glycobiology / Padmaparna Chaudhuri, Rania Harfouche, Shiladitya Sengupta -- Biomarkers of Injury/Disease. Biomarkers of Alzheimer's and Parkinson's Disease / Walter Maetzler, Daniela Berg -- Biomarkers of Cardiac Injury / Anthony S McLean, Stephen J Huang -- Lung Injury Biomarkers / Urmila P Kodavanti -- Translational Biomarkers of Acute Drug-Induced Liver Injury: The Current State, Gaps, and Future Opportunities / Josef S Ozer, William J Reagan, Shelli Schomaker, Joe Palandra, Mike Baratta, Shashi Ramaiah -- Biomarkers of Acute Kidney Injury / Frank Dieterle, Frank D Sistare -- Technology for Biomarker Detection. In Search of Biomarkers for Drug-Induced Vascular Injury / James R Turk -- Biomarkers of Immunotoxicity / Rodney R Dietert -- Biomarkers in Obstetric Medicine / Manish Maski, Sarosh Rana, S Ananth Karumanchi -- Biomarkers in Cancer / Roopali Roy, Christine M Coticchia, Jiang Yang, Marsha A Moses -- Biomarkers of HIV / Lewis Kaufman, Michael J Ross -- Biomarkers of in Vitro Drug-Induced Mitochondrial Dysfunction / James A Dykens, Yvonne Will -- Immunoassay-Based Technologies for the Measurement of Biological Materials Used for Biomarkers Discovery and Translational Research / Vincent Ricchiuti -- Nanoscale Techniques for Biomarker Quantification / Madhukar Varshney, Harold G Craighead -- Immunodiagnostics with a Focus on Lateral Flow Point-of-Care Devices / Roy R Mondesire, Glen M Ford, Hannie F Ford, Stephen C Mefferd -- Hot Topics in Biomarker Research. Biomarkers for Environmental Exposure / Jane E Gallagher, Elaine A Cohen Hubal, Stephen W Edwards -- Clinical Study Design in Biomarker Research / Orfeas Liangos, Bertrand L Jaber -- Statistical Issues in Biomarker Research / Daniel Holder, Matthew Schipper -- Regulatory Perspective for Biomarker Qualification From the U.S. FDA / Federico Goodsaid -- The European Medicines Agency Approach / Marisa Papaluca Amati, Spiros Vamvakas.
    Weitere Ausg.: Print version: Biomarkers. Hoboken, N.J. : Wiley, ©2010 ISBN 9780470452240
    Sprache: Englisch
    Schlagwort(e): Electronic books. ; Electronic books. ; Electronic books.
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    UID:
    gbv_1606613596
    Umfang: XXVIII, 602 S., [8] Bl. , Ill., graph. Darst. , 25 cm
    ISBN: 0470452242 , 9780470452240
    Inhalt: "This book provides an introduction to the field of biomarkers, how they have been and can be used, and how different approaches can be used to identify, characterize, and monitor biomarkers. The book has chapters on topics including HIV, Cancer, Parkinson's, vascular injury, environmental exposure. A following section discusses the technologies (diagnostics and assays) to detect biomarkers and authors have emphasized the preclinical and clinical manifestation of the injury/disease process"--Provided by publisher
    Inhalt: "This book provides an introduction to the field of biomarkers, how they have been and can be used, and how different approaches can be used to identify, characterize, and monitor biomarkers. The book has chapters on topics including HIV, Cancer, Parkinson's, vascular injury, environmental exposure. A following section discusses the technologies (diagnostics and assays) to detect biomarkers and authors have emphasized the preclinical and clinical manifestation of the injury/disease process"--Provided by publisher
    Anmerkung: Formerly CIP Uk , (Publisher-supplied data) 1 (Biomarkers: An Evolutionary Perspective (Michael Ferguson & Vishal Vaidya) -- 2 (Genomics (Weida Tong and Donna L. Mendrick) -- 3 (Proteomics for Biomarker Discovery (Timothy D. Veenstra) -- 4 (Metabolic Profiling for Biomarker Discovery (Hector C. Keun) -- 5 (The Bittersweet Promise of Glycobiology (Padmaparna Chaudhuri, Rania Harfouche, Shiladitya Sengupta) -- 6 (Biomarkers of Alzheimer?s and Parkinson?s Disease (Walter Maetzler, Daniela Berg) -- 7 (Biomarkers of Cardiac Injury (Anthony S. McLean and Stephen J. Huang) -- 8 (Lung Injury Biomarkers (Urmila P. Kodavanti) -- 9 (Translational Biomarkers of Acute Drug Induced Liver Injury: The Current State, Gaps and Future Opportunities (Josef Ozer, William Reagan, Sheli Schomaker, Joe Palandra, Mike Baratta and Shashi Ramaiah) -- 10 (Biomarkers of Acute Kidney Injury (Frank Dieterle and Frank Sistare) -- 11 (In Search of Biomarkers for Drug-induced Vascular Injury (James R. Turk) -- 12 (Biomarkers of Immunotoxicity (Rodney R. Dietert) -- 13 (Biomarkers in Obstetric Medicine (Manish Maski, Sarosh Rana and S. Ananth Karumanchi (NA (0) -- 14 (Biomarkers in Cancer (Roopali Roy, Christine M. Coticchia, Jiang Yang and Marsha A. Moses) -- 15 (Biomarkers of HIV (Lewis Kaufman and Michael J Ross ) -- 16 (Biomarkers of Drug-Induced Mitochondrial Dysfunction (James Dykens and Yvonne Will) -- 17 (Immunoassay-based technologies for the measurement of biological materials used for biomarkers discovery and translational research (Vincent Ricchiuti ) -- 18 (Nanoscale Techniques for Biomarker Quantification (Madhukar Varshney, Harold G. Craighead) -- 19 (Immunodiagnostics with a Focus on Lateral Flow Point-of-Care Devices (Roy R. Mondesire, Glen M. Ford, Hannie F. Ford, Stephen C. Mefferd) -- 20 (Regulatory perspective for biomarker qualification from US-FDA (Federico Goodsaid) -- 21 (The European Medicines Agency approach (Marisa Papaluca-Amati and Spiros Vamvakas) -- 22 (Biomarkers for Environmental Exposure (Jane E. Gallagher, Elaine A. Cohen Hubal and Stephen W. Edwards) -- 23 (Clinical Study Design in Biomarker Research (Orfeas Liangos & Bertrand L. Jaber) -- 24 (Statistical Issues in Biomarker Research (Daniel Holder and Matthew Schipper).
    Weitere Ausg.: Onlineausg. Biomarkers Hoboken, NJ : Wiley, 2010 ISBN 9780470918562
    Weitere Ausg.: Erscheint auch als Online-Ausgabe Vaidya, Vishal S Biomarkers Hoboken : John Wiley & Sons, Incorporated, 2010 ISBN 9780470918555
    Sprache: Englisch
    Fachgebiete: Medizin
    RVK:
    Schlagwort(e): Biomarker ; Biomarker ; Arzneimittelentwicklung
    URL: Cover
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Online-Ressource
    Online-Ressource
    Hoboken, N.J. :Wiley,
    UID:
    edoccha_BV040483546
    Umfang: 1 Online-Ressource (XXVIII, 602 S.).
    ISBN: 9780470918562
    Anmerkung: Includes bibliographical references and index
    Weitere Ausg.: Erscheint auch als Druck-Ausgabe, Hardcover ISBN 978-0-470-45224-0
    Sprache: Englisch
    Fachgebiete: Medizin
    RVK:
    RVK:
    RVK:
    Schlagwort(e): HIV-Infektion ; Krebs ; Parkinson-Krankheit ; Umwelttoxikologie ; Biomarker ; Biomarker ; Umweltüberwachung ; Arzneimitteldesign ; Diagnostik ; Aufsatzsammlung
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    Online-Ressource
    Online-Ressource
    Hoboken, N.J. :Wiley,
    UID:
    almafu_BV040483546
    Umfang: 1 Online-Ressource (XXVIII, 602 S.).
    ISBN: 9780470918562
    Anmerkung: Includes bibliographical references and index
    Weitere Ausg.: Erscheint auch als Druck-Ausgabe, Hardcover ISBN 978-0-470-45224-0
    Sprache: Englisch
    Fachgebiete: Medizin
    RVK:
    RVK:
    RVK:
    Schlagwort(e): HIV-Infektion ; Krebs ; Parkinson-Krankheit ; Umwelttoxikologie ; Biomarker ; Biomarker ; Umweltüberwachung ; Arzneimitteldesign ; Diagnostik ; Aufsatzsammlung
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 5
    Online-Ressource
    Online-Ressource
    Hoboken, N.J. :Wiley,
    UID:
    edoccha_9958129696602883
    Umfang: 1 online resource (648 p.)
    Ausgabe: 1st ed.
    ISBN: 1-282-88375-5 , 9786612883750 , 0-470-91856-X , 0-470-91855-1
    Inhalt: "This book provides an introduction to the field of biomarkers, how they have been and can be used, and how different approaches can be used to identify, characterize, and monitor biomarkers. The book has chapters on topics including HIV, Cancer, Parkinson's, vascular injury, environmental exposure. A following section discusses the technologies (diagnostics and assays) to detect biomarkers and authors have emphasized the preclinical and clinical manifestation of the injury/disease process"--Provided by publisher.
    Anmerkung: Description based upon print version of record. , Biomarkers: In Medicine, Drug Discovery, and Environmental Health; CONTENTS; Preface; Contributors; 1 Biomarkers: An Evolutionary Perspective; SECTION I: TOOLS FOR BIOMARKER DISCOVERY; 2 Genomics; Introduction; Evaluation of the Technology; Clinical Applications; Bioinformatics Challenges; Applications to Drug Toxicology, Medicine, and Environmental Health; Improve Understanding of Basic Cellular Architecture and Function; Mechanism of Toxicity and Disease; Algorithmic Models to Predict Toxicity or Disease; Strengths, Weaknesses, and the Road Forward; Conclusion; Summary Points; Disclaimer , References3 Proteomics for Biomarker Discovery; Introduction; Tissue or Biofluid; Technology; Protein Identification Using Mass Spectrometry; Sample Preparation; Protein Quantitation; Examples of Biomarker Discovery and Evaluation; Challenges in Proteomic Biomarker Discovery; The Road Forward: Targeted Verification and Validation; Conclusion; Summary Points; Acknowledgments; References; 4 Metabolic Profiling for Biomarker Discovery; Introduction: What is Metabolic Profiling?; Analytical Strategies for Metabolic Profiling; Data Pre-Processing, Analysis, and Pattern Recognition , Preclinical Toxicology: Models for Pathological Biomarker DiscoveryDisease Biomarker Discovery Using Metabolic Profiling; Inborn Errors of Metabolism; Neuroscience; Cancer; Infectious Disease; Metabolic Syndrome: Insulin Resistance, Cardiovascular Disease, and Hypertension; Environmental Health and Metabolic Profiling; Conclusion: Strengths, Weaknesses, and the Way Forward for Metabolic Profiling in Biomarker Discovery; Summary Points; References; 5 The Bittersweet Promise of Glycobiology; Introduction; Glycosylation in Pathological States; Congenital Disorders of Glycosylation (CDG) , Glycomics of Immune DisordersGlycomics in Cancer; Other Acquired Diseases; Glycans in Therapeutics and as Therapeutic Targets; Tools to Analyze the Glycome; Analytical; Chemical; Microarray; Molecular; Strengths, Weaknesses, and the Road Forward; Conclusion; Summary Points; References; SECTION II: BIOMARKERS OF INJURY/DISEASE; 6 Biomarkers of Alzheimer's and Parkinson's Disease; Definition and Prevalence of Alzheimer's and Parkinson's Disease; Alzheimer's Disease; Parkinson's Disease; Pathophysiology and Mechanisms; Alzheimer's Disease; Genetic Aspects; Pathology , Pathophysiological MechanismsParkinson's Disease; Genetic Aspects; Pathology; Pathophysiological Mechanisms; Concluding Remarks to Pathological and Pathophysiological Aspects; Current Means for Diagnosis/Prognosis of the Diseases and Their Limitations; Alzheimer's Disease; Clinical Markers; Genetic Markers; In Vivo Markers from Pathology; Pathophysiological Mechanisms; Further Diagnostic Assessments; Parkinson's Disease; Clinical Markers; Genetic Markers; In Vivo Markers from Pathology; Pathophysiological Mechanisms; Further Diagnostic Assessments; Novel Biomarkers; Alzheimer's Disease , Clinical Markers , English
    Weitere Ausg.: ISBN 0-470-45224-2
    Sprache: Englisch
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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