UID:
almafu_9959326900102883
Format:
1 online resource
ISBN:
9781118683859
,
1118683854
,
9781118683057
,
1118683056
,
9781118695692
,
1118695690
,
0470512180
,
9780470512180
Content:
Of the myriad of heterocycles known to man, the indole ring stands foremost for its remarkably versatile chemistry, its enormous range of biological activities, and its ubiquity in the terrestrial and marine environments. The indole ring continues to be discovered in natural products and to be employed in man-made pharmaceuticals and other materials. Given the enormous resurgence in indole ring synthesis over the past decade - highlighted by the power of transition metal catalysis - this authoritative guide addresses the need for a comprehensive presentation of the myriad of methods for constructing the indole ring, from the ancient to the modern, and from the obscure to the well-known. Following presentation of the classic indole ring syntheses and many newer methods, coverage continues with indole ring syntheses via pyrroles, indolines, oxindoles, isatins, radical and photochemical reactions, aryne cycloadditions. This extensive volume concludes with the modern transition metal-catalyzed indole ring syntheses that utilize copper, palladium, rhodium, gold, ruthenium, platinum, and other metals to fashion the indole ring Indole Ring Synthesis is a comprehensive, authoritative and up-to-date guide to the synthesis of this important heterocycle for organic chemists, pharmaceutical researchers and those interested in the chemistry of natural products.
Note:
Intro; Title Page ; Copyright Page; About the Author ; Preface ; Contents; Chapter 1 Introduction; PART I Sigmatropic Rearrangements; PART II Nucleophilic Cyclization ; PART III Electrophilic Cyclization; PART IV Reductive Cyclization; PART V Oxidative Cyclization ; PART VI Radical Cyclization; PART VII Cycloaddition and Electrocyclization; PART VIII Indoles from Pyrroles; PART IX Indoles from Indolines; PART X Metal-Catalyzed Indole Synthesis ; PART XI Miscellaneous; Index; EULA; 1.1 Preview; 1.2 Indole-Containing Natural Products ; 1.3 Biological Activity of Indoles.
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1.4 Indole-Containing Pharmaceuticals 1.5 Indole-Containing Materials ; 1.6 Indole-Containing Ligands ; 1.7 Reviews of Indole-Ring Synthesis; References; Chapter 2 Fischer Indole Synthesis; Chapter 3 Gassman Indole Synthesis; Chapter 4 Bartoli Indole Synthesis; Chapter 5 Thyagarajan Indole Synthesis; Chapter 6 Julia Indole Synthesis; Chapter 7 Miscellaneous Sigmatropic Rearrangements; Chapter 8 Madelung Indole Synthesis; Chapter 9 Wittig-Madelung Indole Synthesis; Chapter 10 Jones-Schmid Indole Synthesis; Chapter 11 Couture Indole Synthesis; Chapter 12 Wender Indole Synthesis.
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Chapter 13 Smith Indole SynthesisChapter 14 Kihara Indole Synthesis; Chapter 15 Nenitzescu 5-Hydroxyindole Synthesis ; Chapter 16 Engler-Kita Indole Synthesis ; Chapter 17 Bailey-Liebeskind-O'Shea Indoline-Indole Synthesis; Chapter 18 Wright Indoline Synthesis; Chapter 19 Saegusa Indole Synthesis; Chapter 20 Ichikawa Indole Synthesis; Chapter 21 Miscellaneous Nucleophilic Cyclizations that Form the Indole Ring; Chapter 22 Sugasawa Indole Synthesis; Chapter 23 Bischler Indole Synthesis; Chapter 24 The Nordlander Indole Synthesis; Chapter 25 Nitrene Cyclization.
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Chapter 40 Reissert Indole SynthesisChapter 41 Leimgruber-Batcho Indole Synthesis; Chapter 42 Pschorr-Hoppe Indole Synthesis; Chapter 43 Mąkosza Indole Synthesis; Chapter 44 Rawal Indole Synthesis; Chapter 45 The Baeyer-Jackson Indole Synthesis and Miscellaneous Reductive Cyclization Indole Syntheses; Chapter 46 Watanabe Indole Synthesis; Chapter 47 Knölker Carbazole Synthesis; Chapter 48 Miscellaneous Oxidative Cyclizations; Chapter 49 Fukuyama Indole Synthesis; Chapter 50 Other Tin-Mediated Indole Syntheses ; Chapter 51 The Murphy Indole Synthesis.
Additional Edition:
Print version: Gribble, Gordon W. Indole ring synthesis. Chichester, West Sussex : John Wiley & Sons, Inc., 2016 ISBN 9780470512180
Language:
English
Keywords:
Electronic books.
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Electronic books.
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Electronic books.
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/9781118695692
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/9781118695692
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/9781118695692
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