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Umfang: 1 Online-Ressource (getrennte Seitenzählung) , Illustrationen

Ausgabe: Version: 20201101

ISBN: 9780750320887 , 9780750320870

Serie: IPEM-IOP series in physics and engineering in medicine and biology

Inhalt: Flow Dynamics and Tissue Engineering of Blood Vessels explores the physical phenomena of vessel compliance and its influence on blood flow dynamics, followed by the modification of flow structures in the presence of diseases within the vessel wall or diseased blood content. This volume also illustrates the progress of tissue engineering for the intervention of re-engineered blood vessels. Blood vessel organoid models, their controlling aspects, and blood vessels based on microfluidic platforms are illustrated following on from the understanding of flow physics of blood on a similar platform. Part of Series in Physics and Engineering in Medicine and Biology.

Weitere Ausg.: ISBN 9780750320863

Weitere Ausg.: ISBN 9780750320894

Weitere Ausg.: Erscheint auch als Druck-Ausgabe Flow dynamics and tissue engineering of blood vessels Bristol : IOP Publishing, 2020 ISBN 9780750320863

Sprache: Englisch

Schlagwort(e): Blutgefäß ; Regenerative Medizin ; Tissue Engineering ; Hämodynamik

DOI: 10.1088/978-0-7503-2088-7

URL: Volltext  (lizenzpflichtig)

URL: Volltext  (lizenzpflichtig)

Mehr zum Autor: Suri, Jasjit S. 1964-

UID:

Umfang: 1 online resource (315 pages)

Ausgabe: 1st ed.

ISBN: 9780750320887

Serie: IPEM-IOP Series in Physics and Engineering in Medicine and Biology Series

Inhalt: The purpose of this book is to provide an overview of regenerative medicine and fluid mechanics principles for the management of clinically diseased blood vessels. Authors discuss tissue engineering aspects and computational fluid mechanical principles, and how they can be used to understand the state of blood vessels in diseased conditions.

Anmerkung: Intro -- Preface -- Editor biographies -- Arindam Bit -- Jasjit S Suri -- Contributors -- Chapter 1 Anatomy and physiology of blood vessels -- 1.1 Introduction -- 1.2 Structure of blood vessel -- 1.2.1 Tunica intima -- 1.2.2 Tunica media -- 1.2.3 Tunica externa -- 1.3 Types of blood vessels -- 1.3.1 Arteries -- 1.3.2 Pulmonary artery -- 1.3.3 Coronary artery -- 1.3.4 Systemic artery -- 1.3.5 Hepatic artery -- 1.3.6 Carotid artery -- 1.3.7 Retinal artery -- 1.3.8 Splenic artery -- 1.3.9 Capillaries -- 1.3.10 Fenestrated capillaries -- 1.3.11 Sinusoidal capillaries -- 1.3.12 Continuous capillaries -- 1.3.13 Veins -- 1.3.14 Pulmonary vein -- 1.3.15 Systemic veins -- 1.3.16 The heart veins -- 1.3.17 The veins of the head and neck -- 1.3.18 The veins present in the exterior part of the head and face -- 1.3.19 The veins in the neck -- 1.3.20 The veins of the brain -- 1.3.21 Opthalmic vein -- 1.3.22 Hepatic vein -- 1.3.23 Splenic vein -- 1.4 Circulatory networks -- 1.4.1 Pulmonary circulation -- 1.4.2 Coronary circulation -- 1.4.3 Systemic circulation -- 1.5 Physiology of blood flow -- 1.5.1 Blood flow between capillaries and tissues -- 1.5.2 Regulation of blood pressure -- 1.5.3 Baroreceptor response -- 1.5.4 Chemoreceptor response -- 1.5.5 Rennin-angiotensin-aldosterine activation system -- 1.5.6 Autoregulation of blood flow -- 1.6 Conclusion -- References -- Chapter 2 Neurovascular structure and function -- 2.1 Introduction -- 2.2 Pathology in neurovascular units -- 2.3 Medial neurovascular structures -- 2.4 Cerebral vascular disease in ischemic stroke -- 2.5 Vascular risk factors -- 2.6 Neurovascular mechanics -- 2.7 Pathology of microvascular components in the NVU -- 2.8 Neurogenesis and neurovascular homeostasis -- 2.9 Neurovascular structure at coronal segment -- 2.10 Neurovascular structure and pathology near the foot. , 2.11 Neurovascular pathology at the shoulder joint -- 2.12 Neurovasculature at the hip joint and meniscus -- 2.13 Conclusion -- References -- Chapter 3 3D bioprinting in tissue engineering and regenerative medicine -- 3.1 Introduction -- 3.2 Types of 3D bioprinting -- 3.2.1 Extrusion-based bioprinting -- 3.2.2 Inkjet bioprinting -- 3.2.3 Laser based bioprinting -- 3.3 Hard tissue engineering -- 3.3.1 Bone -- 3.3.2 Cartilage -- 3.4 Soft tissue engineering -- 3.4.1 Vascular tissue -- 3.4.2 Skin -- 3.5 Tissue engineering for application in specific organs -- 3.5.1 Liver -- 3.5.2 Kidney -- 3.5.3 Bladder -- 3.5.4 Retina -- 3.6 Conclusion -- References -- Chapter 4 Numerical analysis of blood flow in vasculature structure -- 4.1 Introduction -- 4.2 Methodology -- 4.2.1 Construction of geometry -- 4.3 Results and discussion -- 4.3.1 Hemodynamics of blood through axi-symmetric aneurismal blood vessel -- 4.3.2 Comparative assessment of hemodynamics of blood in a stenosed or aneurismal vessel -- 4.4 Conclusion -- References -- Chapter 5 Numerical analysis of blood flow in a micro-capillary in in vitro conditions -- 5.1 Introduction -- 5.2 Methodology -- 5.2.1 Micro-viscometer study -- 5.3 Numerical modeling -- 5.4 Grid independence study -- 5.5 Results and discussions -- 5.5.1 Evaluation of fluid flow parameter in a microviscometer -- 5.6 Numerical assessment of the rheological model for blood flowing in an inclined plane -- 5.7 Discussion -- 5.8 Conclusion -- References -- Chapter 6 Experimental analysis of blood flow in vessels with pathological conditions -- 6.1 Introduction -- 6.2 Methodology -- 6.2.1 Overview of experimental table -- 6.2.2 lDV principle -- 6.3 Laser head -- 6.4 Plasma tube -- 6.5 Power supply -- 6.6 Multi-colour beam splitter -- 6.7 Fiber optic transmitter probe -- 6.8 Photo detector module -- 6.9 FSA signal processor -- 6.10 Down-mixer. , 6.11 Burst acquisition system -- 6.12 Photo multiplier tube voltage -- 6.13 Burst threshold -- 6.14 SNR and downmixing frequency -- 6.15 Noise in LDV -- 6.16 Test bench of blood vessel -- 6.17 Result -- 6.17.1 Analysis of stenosis influence length -- 6.18 Uncertainty analysis -- 6.18.1 Shifted frequency of reflected light at the receiver (fr) -- 6.19 Conclusion -- References -- Chapter 7 Biomaterials for a synthetic and tissue engineered blood vessel -- 7.1 Introduction -- 7.2 Blood-biomaterial interaction -- 7.3 Synthetic polymer -- 7.4 Natural polymer -- 7.5 Decellularized matrix -- 7.6 Hybrid material -- 7.7 Assessment of practical use of a vascular graft -- 7.8 Conclusion -- References -- Chapter 8 3D printing technology, bioink, fabrication technique of blood vessel and system used for cell culturing -- 8.1 Introduction -- 8.2 3D printing technology for tissue engineering -- 8.2.1 Fused deposition modelling (FDM) -- 8.2.2 Selective laser sintering: the laser based -- 8.2.3 Stereolithography -- 8.2.4 Laser metal deposition -- 8.2.5 Digital laser processing -- 8.2.6 Jet-based bioprinting technology -- 8.2.7 Inkjet printing -- 8.2.8 Micro-valve printing -- 8.2.9 Acoustic printing -- 8.2.10 Laser-assisted printing -- 8.2.11 Electrospun -- 8.2.12 Electrohydrodynamic jet printing -- 8.3 Bio-ink/Biomaterial -- 8.3.1 Criteria for selection of biomaterial -- 8.3.2 Types of biomaterials -- 8.4 Blood vessel formation using a 3D printer -- 8.4.1 Anatomy of a blood vessel -- 8.4.2 Self-assembly approach -- 8.4.3 Extrusion-based 3D printing system with rotatory printing device -- 8.4.4 Drop and demand method -- 8.4.5 Hydrogel bio-printed micro-channel -- 8.4.6 Laser-based 3D bioprinting of a blood vessel -- 8.4.7 Embedded bioprinting for vascular engineering -- 8.5 Importance of bioreactors -- 8.6 Conclusion -- References. , Chapter 9 Blood flow evaluation in different circulatory systems -- 9.1 Introduction -- 9.2 Methodology -- 9.3 Results and discussions -- 9.4 Conclusion -- References -- Chapter 10 Fabrication techniques of artificial blood vessels -- 10.1 Introduction -- 10.2 Cell types used for blood vessel regeneration -- 10.3 Techniques for the regeneration of blood vessels -- 10.3.1 Scaffold-free technology -- 10.3.2 Freeze drying -- 10.3.3 Decellularized vascular graft -- 10.4 Bioprinting technique -- 10.5 Electrospinning -- 10.6 Hybrid scaffold fabrication technique -- 10.7 Characterization of an artificial blood vessel -- 10.8 Mechanical properties of an artificially fabricated blood vessel by different techniques -- 10.9 Conclusion -- References -- Chapter 11 Bioreactors for tissue engineered blood vessels -- 11.1 Introduction -- 11.2 Properties of a bioreactor -- 11.3 Blood vessel bioreactors -- 11.3.1 Pulsatile perfusion bioreactor -- 11.3.2 Biaxial bioreactor -- 11.3.3 VascuTrainer bioreactor -- 11.3.4 Perfusion bioreactor with longitudinal stretch -- 11.3.5 Pulsatile flow bioreactors -- 11.3.6 Bioreactor with cyclic strain -- 11.3.7 Multi-cue bioreactor -- 11.4 Bioreactors specifically designed for tissue engineered heart valves -- 11.4.1 Cardiac valve bioreactor -- 11.4.2 Pulsatile bioreactors for cardiac valves -- 11.5 Conclusion -- References -- Chapter 12 An artificial blood vessel and its controlling aspects-I -- 12.1 Introduction -- 12.2 Formation of blood vessels in the human body -- 12.3 New capillaries formed from sprouting -- 12.4 Angiogenesis controlling factors -- 12.5 Functions of blood vessels -- 12.6 Biological control of blood vessel structure and its effects on various physiological parameters -- 12.7 Need for artificial blood vessels -- 12.7.1 Buerger's disease -- 12.7.2 Peripheral venous disease and varicose veins. , 12.7.3 Raynaud's disease or Raynaud's syndrome -- 12.8 Development of artificial blood vessels through tissue engineering -- 12.9 Vascular tissue regeneration -- 12.9.1 Decellularized matrices based scaffolds -- 12.9.2 Scaffolds from natural polymers -- 12.9.3 Scaffolds from biodegradable synthetic polymers -- 12.9.4 Synthetic and natural scaffolds -- 12.9.5 Hybrid scaffolds from synthetic and natural polymers -- 12.9.6 TEVGs without scaffolds -- 12.10 Selection of biomaterials and design parameters -- 12.11 Biomaterials preferred for preparing vascular grafts -- 12.11.1 Synthetic nondegradable polymers (ePTFE, dacron and polyurethanes) -- 12.11.2 Polymer functionalization -- 12.11.3 Degradable scaffolds -- 12.11.4 Biopolymers -- 12.11.5 Nanocomposites -- 12.11.6 Alternative tissue sources -- 12.12 Controlling factors and functional requirements in blood vessel tissue engineering -- 12.12.1 Mechanical requirements -- 12.12.2 Biological requirements -- 12.13 Vascular grafts and their main applications -- References and further reading -- Chapter 13 Control aspects of the circulatory system -- 13.1 Introduction -- 13.2 Passive control system of circulatory system -- 13.2.1 The ventricles -- 13.2.2 The atria -- 13.2.3 The systemic and pulmonary vessels -- 13.3 Neural and humoral control system -- 13.3.1 Baroreceptor reflexes -- 13.3.2 Input-output relationship of the baroreceptor -- 13.4 Transformation of afferent baroreceptor signals into heart rate -- 13.4.1 Control of cardiac contractility -- 13.4.2 Sympathetic control of fluid resistance of systematic arterioles -- 13.4.3 Control of systemic venous volume -- 13.4.4 Model of cardiovascular control loop -- 13.5 Behaviour of the controlled cardiovascular system -- 13.5.1 Cardiac rhythm caused by the LV assist pump -- 13.5.2 Animal experiment -- 13.5.3 Role of circulatory system in LV by-pass surgery. , 13.6 Cardiovascular circulatory system and assist pump model.

Weitere Ausg.: Print version: Bit, Arindam Flow Dynamics and Tissue Engineering of Blood Vessels Bristol : Institute of Physics Publishing,c2020 ISBN 9780750320894

Sprache: Englisch

Schlagwort(e): Electronic books.

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UID:

Umfang: 1 online resource (various pagings) : , illustrations (some color).

ISBN: 9780750320887 , 9780750320870

Serie: IPEM-IOP series in physics and engineering in medicine and biology

Inhalt: Flow Dynamics and Tissue Engineering of Blood Vessels explores the physical phenomena of vessel compliance and its influence on blood flow dynamics, followed by the modification of flow structures in the presence of diseases within the vessel wall or diseased blood content. This volume also illustrates the progress of tissue engineering for the intervention of re-engineered blood vessels. Blood vessel organoid models, their controlling aspects, and blood vessels based on microfluidic platforms are illustrated following on from the understanding of flow physics of blood on a similar platform. Part of Series in Physics and Engineering in Medicine and Biology.

Anmerkung: "Version: 20201101"--Title page verso. , 1. Anatomy and physiology of blood vessels / Arindam Bit, Jasjit S. Suri and Achalla Ranjani -- 2. Neurovascular structure and function / Arindam Bit, Jasjit S. Suri and Bharti Mishra -- 3. 3D bioprinting in tissue engineering and regenerative medicine / Arindam Bit, Jasjit S. Suri and Sharda Gupta -- 4. Numerical analysis of blood flow in vasculature structure / Arindam Bit and Jasjit S. Suri -- 5. Numerical analysis of blood flow in a micro-capillary in in vitro conditions / Arindam Bit and Sonali Gore -- 6. Experimental analysis of blood flow in vessels with pathological conditions / Arindam Bit and Jasjit S. Suri -- 7. Biomaterials for a synthetic and tissue engineered blood vessel / Arindam Bit, Jasjit S. Suri and Sharda Gupta -- 8. 3D printing technology, bioink, fabrication technique of blood vessel and system used for cell culturing / Arindam Bit, Jasjit S. Suri and Khemraj Desmukh -- 9. Blood flow evaluation in different circulatory systems / Arindam Bit and Jasjit S. Suri -- 10. Fabrication techniques of artificial blood vessels / Arindam Bit, Jasjit S. Suri and Sharda Gupta -- 11. Bioreactors for tissue engineered blood vessels / Arindam Bit, Jasjit S. Suri and Khemraj Deskmukh -- 12. An artificial blood vessel and its controlling aspects--I / Jasjit S. Suri, Karabi Ganguly and Swati Sikdar -- 13. Control aspects of the circulatory system / Arindam Bit, Jasjit S. Suri and Khemraj Deshmukh -- 14. Control aspects of a heart assistive device / Arindam Bit, Jasjit S. Suri and Khemraj Deshmukh. , Also available in print. , Mode of access: World Wide Web. , System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader.

Weitere Ausg.: Print version: ISBN 9780750320863

Weitere Ausg.: ISBN 9780750320894

Sprache: Englisch

DOI: 10.1088/978-0-7503-2088-7

URL: https://iopscience.iop.org/book/978-0-7503-2088-7