UID:
almafu_9961085833502883
Umfang:
1 online resource (290 p.)
Ausgabe:
1st ed.
ISBN:
9781118316313
,
1118316312
,
9781118316290
,
1118316290
,
9781118316320
,
1118316320
Originaltitel:
Osteoporosis (2013)
Inhalt:
Osteoporosis is a growing major public health problem that impacts many women and men. In the US alone, it is estimated that 10 million Americans have osteoporosis and another 34 million have low bone mass. Both of these conditions put patients at increased risk for fracture. This book takes a ""generalist"" approach to the challenge of osteoporosis. It is aimed at those specialists, in particular gynecologists, who have regular clinical contact with particularly prone populations, such as menopausal and post menopausal women, who do not have the need for in-depth knowledge of the subject.
Anmerkung:
Description based upon print version of record.
,
Osteoporosis; Contents; List of Contributors; Preface; Chapter 1 Epidemiology and Genetics of Postmenopausal Osteoporosis; Introduction; Genetics; Heritability estimates in osteoporosis; Genetic studies in osteoporosis; Genes involved in osteoporosis; Early life, gene-environment interactions and epigenetics; Environmental influences in childhood; Fracture epidemiology; Geography; Secular trends; Conclusion; Acknowledgements; References; Chapter 2 Osteoporosis in Men; Introduction; Epidemiology; Classification and pathophysiology; Diagnosis and evaluation of men at risk for osteoporosis
,
Treatment of men with osteoporosisReferences; Chapter 3 Mechanisms of Bone Remodeling; Introduction; The bone remodeling cycle; Osteoclast differentiation; Osteoblast differentiation; Coupling between resorption and formation; The bone remodeling compartment; Bone remodeling in osteoporosis; Changes in bone remodeling during menopause; Age dependent bone loss; Bone remodeling in secondary osteoporosis; Conclusion; References; Chapter 4 Fracture Risk Assessment; Fracture risk assessment; Estimating the fracture risk based on BMD; Bone geometry and fracture risk; Age and fracture risk
,
Bone turnover and fracture riskOther factors and fracture risk; The FRAX® tool; FRAX can be used to make management decisions; FRAX cannot be used for following up patients; Response to risk factors is dichotomized; FRAX® uses BMD of the femoral neck; Several risk factors increasing the risk of fractures are not included in FRAX®; FRAX® can be calculated without BMD; FRAX® is a work in evolution; The Garvan Fracture Risk Calculator (FRC); Conclusion; Disclosures; Acknowledgements; References; Chapter 5 Secondary Causes of Osteoporosis: Bone Diseases; Introduction; Pathophysiology
,
Endocrine diseasesGastrointestinal diseases; Bariatric surgery; Hematological and immunological diseases; Myeloma bone disease and monoclonal gammopathy of undetermined significance; HIV disease and Highly Active Antiretroviral Therapy (HAART); Gaucher disease; Diagnosis; Management of secondary osteoporosis; Treatment of the underlying disease; General measures; Specific osteoporosis treatment; Conclusion; Disclosure; Acknowledgements; References; Chapter 6 Glucocorticoid-induced Osteoporosis; Introduction; Epidemiology; FRAX; Workup; Pathophysiology; Treatment
,
Treatment with oral bisphosphonatesTreatment with other agents; Treatment with intravenous bisphosphonates; Treatment with bone formation agents; Guidelines for managing GIO; IOF guidelines; References; Chapter 7 Secondary Causes of Osteoporosis: Other Medications; Introduction; Aromatase inhibitors; Antidepressants; Anti-epileptic drugs; Calcineurin inhibitors; Depot medroxyprogesterone acetate; GnRH agonists; Proton pump inhibitors; Thiazolidinediones; Summary; References; Chapter 8 Hormone Therapy for Osteoporosis; Inroduction; Mechanism of action; The effect of estrogen therapy on bone
,
Changes in bone mineral density
,
English
Weitere Ausg.:
ISBN 9781119968917
Weitere Ausg.:
ISBN 1119968917
Weitere Ausg.:
ISBN 9781299743267
Weitere Ausg.:
ISBN 1299743269
Sprache:
Englisch
Bookmarklink
