Umfang:
Online-Ressource (XIV, 396 p. 92 illus., 54 illus. in color, digital)
ISBN:
9781627030359
,
1283624796
,
9781283624794
Serie:
SpringerLink
Inhalt:
The Centrosome: Cell and Molecular Mechanisms of Functions and Dysfunctions in Disease includes chapters on classic and modern aspects of centrosome research to cover topics of current interest that have not been covered in depth in most books on the market so far. It extends on previous topics and includes new exciting aspects of centrosome research focused on primary cilia and their dysfunctions that are implicated in numerous diseases. Each chapter will be written by experts in their fields who will contribute their unique expertise in specific research fields and include cell and molecular details that are important for the specific subtopics. The book will be comprehensive, concise and will include reviews of key topics in the field. Cutting edge new information will be balanced with background information that will be readily understandable for the newcomer and the experienced centrosome researcher alike.
Anmerkung:
Description based upon print version of record
,
The Centrosome; Preface; Contents; Contributors; Part I Centrosomes in Reproduction; 1 Centriole Duplication and Inheritance in Drosophila melanogaster; Abstract; 1.1…What are the Challenges in Studying the Centrosome and Why Use Drosophila?; 1.2…Centrosomes in Drosophila Development; 1.2.1 FertilizationFertilization; 1.2.2 Syncytial Development; 1.2.3 The Drosophila Zygote and Syncytial Blastoderm Develop Using Proteins Generated in the Mother; 1.3…Centrosomes in Differentiated Cells; 1.3.1 Sensory neuron differentiation; 1.3.2 Spermatogenesis
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1.3.3 The Drosophila Adult Sensory Neuron and Testes Develop Using Proteins Generated During Metamorphosis1.3.4 Phenotypic Characterization of Centrosomal Mutants; 1.4…The Role of the Centrosome; 1.5…Two Pathways of Centriole Formation; 1.6…Identification of Centrosomal Proteins and Mutants in Drosophila melanogaster; 1.6.1 Anti-Centrosomal Antibodies; 1.6.2 Reverse Genetics; 1.6.3 Bioinformatic subtractive screen for ciliary and centrosomal proteins; 1.6.4 Male Sterile Mutants; 1.6.5 Mechanosensory Mutants; 1.6.6 PCL Mutants; 1.7…Identification of Centrosomal Complexes; Acknowledgments
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References2 Sperm Centrioles and Their Dual Role in Flagellogenesis and Cell Cycle of the Zygote; Abstract; 2.1…Centrosomes, Centrioles, and Basal Bodies; 2.2…Sperm Pathologies in Infertile Men with Special Reference to Those Related to Centrioles and Centrosomes; Acknowledgments; References; 3 Centrosomal Functions and Dysfunctions in Cat Spermatozoa; Abstract; 3.1…Introduction; 3.2…Centrosomal Immaturity in Cat Testicular Spermatozoa; 3.3…Causes of Centrosomal Dysfunctions in Cat Spermatozoa; 3.3.1 Impact of Teratospermia; 3.3.2 Impact of Classical and Emerging Preservation Techniques
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3.4…Mitigating Centrosomal Immaturity and Dysfunctions3.4.1 Sperm Micromanipulations and Selections; 3.4.2 Centrosomal Maturation In Vitro; 3.5…Conclusions; Competing Interests; References; 4 Nuclear--Centrosome Relationships During Fertilization, Cell Division, Embryo Development, and in Somatic Cell Nuclear Transfer Embryos; Abstract; 4.1…Introduction; 4.2…The Sperm Centriole--Centrosome Complex and Associations with the Sperm Nucleus Before Fertilization; 4.3…CentrosomeCentrosome--Nuclear Relationships During Pronuclear/Zygote Stage, Cell Division, and Embryo Development
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4.4…CentrosomeCentrosome--Nuclear Interactions and Reprogramming Abnormalities in Somatic Cell Nuclear Transfer Embryos4.5…Conclusion and Future Perspectives; References; 5 Human Centrosomal Dynamics During Gametogenesis, Fertilization, and Embryogenesis and Its Impact on Fertility: Ultrastructural Analysis; Abstract; 5.1…Introduction; 5.2…Ultrastructure; 5.3…Methodology; 5.4…Gamete Centrosomes; 5.5…The Paternal Centrosome (Centriole); 5.6…The Maternal Centrosome; 5.7…The Zygote Centrosome; 5.8…Centrioles in Embryos; 5.9…Centriolar Duplication; 5.10…Molecular Aspects
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5.11…Sperm Centrosomes and Infertility
Weitere Ausg.:
ISBN 9781627030342
Weitere Ausg.:
Buchausg. u.d.T. ISBN 978-1-627-03034-2
Sprache:
Englisch
DOI:
10.1007/978-1-62703-035-9
URL:
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