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  • 1
    Online Resource
    Online Resource
    Dordrecht :Springer Netherlands :
    UID:
    almahu_9949198503702882
    Format: VII, 333 p. , online resource.
    Edition: 1st ed. 2004.
    ISBN: 9781402023378
    Content: In spite of important advances in asymmetric synthesis, chiral compounds cannot all be obtained in a pure state by asymmetric synthesis. As a result, enantiomer separation remains an important technique for obtaining optically active materials. Although asymmetric synthesis is a once-only procedure, an enantiomer separation process can be repeated until the optically pure sample is obtained. This book discusses several new enantiomer separation methods using modern techniques developed by experts in the field. These methods consist mainly of the following three types: 1) Enantiomer separation by inclusion complexation with a chiral host compound 2) Enantiomer separation using biological methods 3) Enantiomer separation by HPLC chromatography using a column containing a chiral stationary phase. Separation of a racemic compound has been called "optical resolution" or simply "resolution". Nowadays, the descriptions "enantiomer resolution" or "enantiomer separation" are also commonly used. Accordingly, "Enantiomer Separation" is used in the title of this book. The editor and all chapter contributors hope that this book is helpful for scientists and engineers working in this field.
    Note: Optical resolutions by inclusion complexation with a chiral host compound -- Crystalline dipeptides: their molecular recognition to be useful to enantiomer separation -- Optical resolution via complex formation with O,O'-dibenzoyltataric acid -- Spontaneous chiral crystallization of achiral materials and absolute asymmetric transformation in the chiral crystalline environment -- Preferential enrichment: a dynamic enantiomeric resolution phenomenon caused by polymorphic transition during crystallization -- Optical resolution by means of crystallization -- Lipase-catalyzed kinetic resolution of racemates: a versatile method for the separation of enantiomers -- Enzymatic kinetic resolution -- Preparative-scale separation of enantiomers on chiral stationary phases by gas chromatography -- Practical resolution of enantiomers by high-performance liquid chromatography.
    In: Springer Nature eBook
    Additional Edition: Printed edition: ISBN 9789048166404
    Additional Edition: Printed edition: ISBN 9781402023361
    Additional Edition: Printed edition: ISBN 9789401751285
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Online Resource
    Online Resource
    Dordrecht : Springer Netherlands
    UID:
    gbv_766648346
    Format: Online-Ressource (VIII, 333 p) , online resource
    Edition: Springer eBook Collection. Chemistry and Materials Science
    ISBN: 9781402023378
    Content: Enantiomer Separation is written by several experts working in modern enantiomer separation chemistry who understand the needs of the many scientific and engineering chemists who need a cost-efficient supply of optically active materials of high quality. This book contains the following modern practical methods of enantiomer separation: Inclusion complexation of a racemic compound with a chiral host compound, which gives chiral host-chiral guest inclusion compounds, from which the chiral guest can be obtained. When this separation is combined with distillation technique, for example, enantiomer separation can be accomplished by fractional distillation in the presence of a chiral host compound. This is a modern and "green" procedure of enantiomer separation. These separation methods are described in several chapters of the book. Biological separation methods and "green" methods are covered in two chapters. Enantiomer separation by chromatography on a column containing chiral solid phase is one of the most up-to-date and well known "green" methods of enantiomer separation. Two experts in chromatography have contributed to provide two very important chapters on this method of separation. Practical methods of enantiomer separation are important both in the research laboratory and in industry, especially in the pharmaceutical, fine chemical and electronic industries. Chemists and engineers, as well as students who are working in the field of chiral compounds in universities, institute and industry, will find this book an invaluable resource
    Additional Edition: ISBN 9781402023361
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 9789048166404
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 9781402023361
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 9789401751285
    Language: English
    URL: Volltext  (lizenzpflichtig)
    Library Location Call Number Volume/Issue/Year Availability
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