Format:
Online-Ressource
,
v.: digital
Edition:
Online-Ausg. Springer eBook Collection. Biomedical and Life Sciences Electronic reproduction; Available via World Wide Web
ISBN:
1283074451
,
9781441963543
,
9781283074452
Series Statement:
Advances in Experimental Medicine and Biology 681
Content:
This book represents the joint effort of an international group of scientists who are at the forefront of research in the field. The volume spans information on chemistry, pharmacology, distribution, and therapeutic potential of melanocortins. A recurrent theme of this volume is the role played by distinct melanocortin receptors in mediating melanocortin effects. Although these receptors have been identified and well-characterized, information in the book indicates that definite categorization of their expression and function in different conditions still needs major work.
Content:
This book represents the joint effort of an international group of scientists who are at the forefront of research in the field. The volume spans information on chemistry, pharmacology, distribution, and therapeutic potential of melanocortins. A recurrent theme of this volume is the role played by distinct melanocortin receptors in mediating melanocortin effects. Although these receptors have been identified and well-characterized, information in the book indicates that definite categorization of their expression and function in different conditions still needs major work
Note:
Includes bibliographical references and index
,
Title Page; Copyright Page; DEDICATION; FOREWORD; PREFACE; ABOUT THE EDITOR...; PARTICIPANTS; Table of Contents; Chapter 1 Structure-Activity Relationships (SAR) of Melanocortin and Agouti-Related (AGRP) Peptides; Chapter 2 Melanocortin Signalling Mechanisms; Chapter 3 Distribution and Function of Melanocortin Receptors within the Brain; Chapter 4 Drugs, Exercise, and the Melanocortin-4 Receptor- Different Means, Same Ends: Treating Obesity; Chapter 5 Melanocortins in Brain Inflammation: The Role of Melanocortin Receptor Subtypes
,
Chapter 6 Melanocortins and the Cholinergic Anti-Inflammatory PathwayChapter 7 Melanocortin Control of Cell Trafficking in Vascular Inflammation; Chapter 8 Terminal Signal: Anti-Inflammatory Effects of a-Melanocyte-Stimulating Hormone Related Peptides Beyond the Pharmacoph; Chapter 9 Protective Effects of Melanocortins in Systemic Host Reactions; Chapter 10 Development of a-Melanocortin Analogs for Melanoma Prevention and Targeting; Chapter 11 MSH Radiopeptides for Targeting Melanoma Metastases; Chapter 12 Applications of the Role of a-MSH in Ocular Immune Privilege; INDEX;
,
Structure-activity relationships (SAR) of melanocortin and agouti-related (AGRP) peptides / Anamika Singh, Erica M. Haslach and Carrie Haskell-Luevano -- Melanocortin signalling mechanisms / Paula C. Eves and John W. Haycock -- Distribution and function of melanocortin receptors within the brain / Kathleen G. Mountjoy -- Drugs, exercise, and the melanocortin-4 receptor : different means, same ends : treating obesity / Jay W. Schaub, Erin B. Bruce, and Carrie Haskell-Luevano -- Melanocortins in brain inflammation : the role of melanocortin receptor subtypes / Ruta Muceniece and Maija Dambrova -- Melanocortins and the cholinergic anti-inflammatory pathway / Daniela Giuliani ... [et al.] -- Melanocortin control of cell trafficking in vascular inflammation / Hetal B. Patel ... [et al.] -- Terminal signal : anti-inflammatory effects of melanocyte-stimulating hormone related peptides beyond the pharmacophore / Thomas Brzoska ... [et al.] -- Protective effects of melanocortins in systemic host reactions / Stefano Gatti ... [et al.] -- Development of melanocortin analogs for melanoma prevention and targeting / Zalfa A. Abdel-Malek -- MSH radiopeptides for targeting melanoma metastases / Alex N. Eberle ... [et al.] -- Applications of the role of MSH in ocular immune privilege / Andrew W. Taylor and Darren Lee.
,
Electronic reproduction; Available via World Wide Web
Additional Edition:
ISBN 1283076551
Additional Edition:
ISBN 9781441963536
Language:
English
DOI:
10.1007/978-1-4419-6354-3
URL:
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