Umfang:
Online-Ressource (XXII, 274p. 65 illus, digital)
ISBN:
9781461403326
Serie:
Advances in Experimental Medicine and Biology 722
Inhalt:
Lesley J. Collins
Inhalt:
RNAs form complexes with proteins and other RNAs. The RNA-infrastructure represents the spatiotemporal interaction of these proteins and RNAs in a cell-wide network. "RNA Infrastructure and Networks" brings together these ideas to illustrate the scope of RNA-based biology, and how connecting RNA mechanisms is a powerful tool to investigate regulatory pathways. This book is but a taste of the wide range of RNA-based mechanisms that connect in the RNA infrastructure
Anmerkung:
Includes bibliographical references and index
,
Title Page; Copyright Page; Dedication Page; PREFACE; ABOUT THE EDITOR; PARTICIPANTS; Table of Contents; ACKNOWLEDGEMENTS; CHAPTER 1 THE RNA INFRASTRUCTURE: An Introduction to ncRNA Networks; Abstract; INTRODUCTION; RNAs PROCESSING OTHER RNAs; SPATIAL REGULATION OF EUKARYOTIC RNA PROCESSING; RNA REGULATION, CONNECTING COMPONENTS OF THE RNA-INFRASTRUCTURE; RNAi Networks; RNA Networks and Epigenetics; RNA Regulation in Prokaryotes; CONCLUSION; ACKNOWLEDGEMENTS; REFERENCES; CHAPTER 2 RNA INTERACTIONS; Abstract; INTRODUCTION; ncRNA-DNA INTERACTIONS; RNA-RNA INTERACTIONS; General Properties
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MicroRNAs and RNA InterferenceSmall Bacterial RNAs and Translational Control; Small Nucleolar RNAs and Chemical Modifications; RNAs in RNA End-Processing; Guide RNAs and RNA Editing; CRISPRs; Ribozymes; ncRNA-PROTEIN INTERACTIONS; Ribonucleoparticles; Long ncRNA as Coat-Hangers?; CONCLUSION; ACKNOWLEDGEMENTS; REFERENCES; CHAPTER 3 PLANT RNA SILENCING IN VIRAL DEFENCE; Abstract; INTRODUCTION; GENERATION OF VIRAL SMALL INTERFERING RNAs: VIRUSES, vsiRNAs AND DICERS; POST-DICING MODIFICATION OF vsiRNAs; ANTIVIRAL EFFECTOR COMPLEXES; AMPLIFICATION AND SPREAD OF ANTIVIRAL DEFENCE
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MOVEMENT OF ANTIVIRAL SILENCINGVIRAL SUPPRESSORS OF RNA SILENCING; CONCLUSION; ACKNOWLEDGEMENTS; REFERENCES; CHAPTER 4 MicroRNAs AS POST-TRANSCRIPTIONAL MACHINES AND THEIR INTERPLAY WITH CELLULAR NETWORKS; Abstract; INTRODUCTION; BIOGENESIS, GENOMIC ORGANIZATION AND EVOLUTION OF miRNAs; METHODS TO IDENTIFY miRNAs AND THEIR TARGETS; MicroRNA INTERPLAY WITH OTHER CELLULAR NETWORKS; EXPRESSION DYNAMICS AND CROSSTALK OF miRNAs WITH OTHER REGULATORY FACTORS; CONCLUSION; ACKNOWLEDGEMENTS; REFERENCES; CHAPTER 5 SPATIOTEMPORAL ASPECTS OF MicroRNA-MEDIATED GENE REGULATION; Abstract; INTRODUCTION
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DNA DAMAGE RESPONSE AS AN EXAMPLE OF MULTILAYERED REGULATIONMicroRNA-MEDIATED GENE SILENCING IN THE DDR; MECHANISM OF FAST MicroRNA REGULATION; LOCALIZATION OF THE MicroRNA-MEDIATED GENE SILENCING MACHINERY; CONCLUSION; REFERENCES; CHAPTER 6 SPLICEOSOMAL RNA INFRASTRUCTURE: The Network of Splicing Components and Their Regulation by miRNAs; Abstract; INTRODUCTION; THE SPLICEOSOME AS AN EXAMPLE OF THE RNA-INFRASTRUCTURE; RNA-PROTEIN INTERACTION NETWORKS; REGULATORY (EXPRESSION MODULATED) NETWORKS; SPATIOTEMPORAL DYNAMIC RNA NETWORKS; CONCLUSION; ACKNOWLEDGEMENTS; REFERENCES
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CHAPTER 7 CONSTRUCTION, STRUCTURE AND DYNAMICS OF POST-TRANSCRIPTIONAL REGULATORY NETWORK DIRECTED BY RNA-BINDING PROTEINSAbstract; INTRODUCTION; RNA BINDING PROTEINS AND POST-TRANSCRIPTIONAL REGULATION; METHODS TO IDENTIFY RBPs AND THEIR TARGETS; RBPs AND POST-TRANSCRIPTIONAL OPERONS; POST-TRANSCRIPTIONAL NETWORK FORMED BY RBPs; EXPRESSION DYNAMICS OF RBPs IN POST-TRANSCRIPTIONAL NETWORKS; CONCLUSION; ACKNOWLEDGEMENTS; SUPPLEMENTARY MATERIAL; REFERENCES; CHAPTER 8 SAFE KEEPING THE MESSAGE: mRNP Complexes Tweaking after Transcription; Abstract; INTRODUCTION; RNP-INFRASTRUCTURE
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POSTTRANSCRIPTIONAL MODULATOR OF GENE EXPRESSION
Weitere Ausg.:
ISBN 9781461403319
Weitere Ausg.:
Buchausg. u.d.T. RNA infrastructure and networks New York, NY [u.a.] : Springer Science+Business Media [u.a.], 2011 ISBN 9781461403319
Sprache:
Englisch
Fachgebiete:
Biologie
Schlagwort(e):
RNS
;
RNS
DOI:
10.1007/978-1-4614-0332-6
URL:
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