UID:
kobvindex_HPB1433204266
Format:
1 online resource (68 p.).
ISBN:
9781612093703
,
1612093701
Series Statement:
Hepatology Research and Clinical Developments Series
Note:
Description based upon print version of record.
,
Intro -- NEW THERAPY FOR LIVERDISEASE BY PLATELETS -- NEW THERAPY FOR LIVERDISEASE BY PLATELETS -- Contents -- Preface -- Chapter 1Introduction -- Chapter 2Promotion ofLiver Regeneration -- A) Platelets Promote LiverRegeneration after Hepatectomy -- Platelet Count -- Liver Regeneration after Hepatectomy -- Platelet Accumulation in the Residual Liver -- B) The Direct Effect of Platelets onHepatocytes -- Proliferative Effect of Platelets on Hepatocytes -- Necessity of Direct Contact with Platelets for HepatocyteProliferation -- Effective Component in Platelets
,
The Characteristics of Direct Contact betweenHepatocytes and Platelets -- Signal Transduction of Hepatocyte Proliferation byPlatelets -- Effective Growth Factors in Platelets on HepatocyteProliferation -- The Mechanism of the Proliferative Effect of Platelets onHepatocyte -- C) The Indirect Effects of Platelets onHepatocytes through SinusoidalEndothelial Cells -- Effect of Platelets on LSECs -- Necessity of Contact with Platelets for Excretion of IL-6from LSECs -- Effective Factor in Platelets on Excretion of IL-6 fromLSECs -- Effects of the Supernatants of LSECs on HepatocyteProliferation
,
Signal Transduction of Hepatocyte Proliferation Activatedby the Supernatant of LSECs -- The Mechanism of the Proliferative Effect of Platelets onHepatocyte through LSECs -- Chapter 3Suppression of Fibrosis inCirrhotic Liver -- Animals, Preparation, and SurgicalProcedure -- Platelet Count -- Liver Regeneration after Hepatectomyin Liver Cirrhosis -- Improvement of Liver Fibrosis -- The Activity of Hepatic Stellate Cells -- The Anti-Fibrotic and Liver Proliferative Effects Are due toIncreased Platelets, Not due to TPO Itself -- Chapter 4Prevention of Hepatitis -- Animals and Model of Hepatitis
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Thrombocytosis Reduces Liver Damage -- Anti-Apoptotic Effect of Thrombocytosis -- Chapter 5The Clinical Trial of PlateletTransfusion in Patients withLiver Cirrhosis -- Protocol -- Subjects -- Follow-up and Adverse Events -- Improvement of Liver Function -- Future Outlook -- Conclusion -- References -- Index
Additional Edition:
Print version: Ohkohchi, Nobuhiro New Therapy for Liver Disease by Platelets New York : Nova Science Publishers, Incorporated,c2013
Language:
English
URL:
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