Format:
1 Online-Ressource (xiv, 269 Seiten)
,
Illustrationen, Diagramme
ISBN:
9781788016216
Series Statement:
Food chemistry, function and analysis 11
Content:
Intro; Half Title; Title; Series Editor; Copyright; Contents; Preface; Chapter 1 Vitamin E: Structure, Properties and Functions 1; 1.1 Introduction; 1.2 Homologues: Nomenclature and Structure; 1.3 Physicochemical Properties; 1.4 Sources; 1.5 Chemical Synthesis; 1.6 Analysis; 1.7 Functions and Applications; 1.8 Stability; References; Chapter 2 Tocotrienols: From Bench to Bedside 12; 2.1 Introduction; 2.2 Physical and Chemical Properties; 2.3 Analysis Method; 2.4 Bioavailability; 2.4.1 Animals; 2.4.2 Humans; 2.5 Safety and Tolerance; 2.6 Nutritional Benefits; 2.6.1 Antioxidant; 2.6.2 Anti-aging
Content:
Providing an overview of the state-of-the-art of the chemistry of vitamin E with regards properties and functions and also nutritional benefits, this is a timely addition to the literature as the centennial anniversary of the discovery of this important vitamin approaches
Content:
2.6.3 Neuroprotection2.6.4 Anti-inflammation; 2.7 Research Gap; 2.8 Conclusion; References; Chapter 3 The Behaviour of Vitamin E in Membranes 32; 3.1 Introduction; 3.2 Membrane Localization, Stabilization, and Fluidity; 3.2.1 Transverse Location of Vitamin E; 3.2.2 DMPC -- The Exception; 3.2.3 Vitamin E Diffusion; 3.2.4 Behavior of Non-α-tocopherols in Bilayers; 3.3 Tocopherol and Lipid "Rafts"; 3.4 The Effect on Membrane-dependent Processes; 3.4.1 Tocopherols; 3.4.2 Tocotrienols; 3.5 Tocol Quinones and Hydroquinones; 3.6 Conclusion; References
Content:
Chapter 4 Chemical Reactivity and Cellular Uptake of Tocopherols and Tocotrienols 514.1 Introduction; 4.2 Reactivities Toward Free Radicals; 4.3 Antioxidant Activities; 4.4 Action of T and T3 as Reductants; 4.5 Physical Effects of T and T3 on Membranes; 4.6 Incorporation of T3 and T into Membranes; 4.7 Cellular Uptake and Distribution of Tocopherols and Tocotrienols; 4.8 Cytoprotective Effects of Tocopherols and Tocotrienols; 4.9 Different Biological Action of Tocopherol Quinones; References; Chapter 5 α-Tocopherol Transfer Protein 64; 5.1 Introduction; 5.2 Vitamin E Transport in the Body
Content:
5.3 Substrate Specificity of α-TTP5.4 α-TTP in Vitamin E Homeostasis: Studies of Ataxia with Vitamin E Deficiency and Knockout Mice; 5.5 Expression of α-TTP in Extrahepatic Tissues; 5.6 Intracellular Vitamin E Transport by α-TTP; 5.7 Role of Phosphoinositides in the Vectorial Transport of α-Tocopherol by α-TTP; 5.8 Future Prospects; References; Chapter 6 Tocopheryl Phosphate 75; 6.1 Introduction; 6.2 Synthesis, Extraction and Analysis of TP; 6.2.1 Chemical Synthesis of TP; 6.2.2 Extraction of TP; 6.2.3 Analyses of Samples Containing TP; 6.3 TP Hydrolysis; 6.4 Biochemical Studies of TP
Content:
6.5 TP as Pro-vitamin E6.6 Biological Synthesis; 6.7 Absorption of TP; 6.8 Safety of TP; 6.9 Effect of TP on Proliferation; 6.10 Effect of TP on Gene Expression and Cell Surface Receptor Localization; 6.10.1 Effect of TP on CD36; 6.10.2 Effect of TP on THP-1 Monocyte Gene Expression; 6.10.3 Effect of TP on NIH3T3-L1 Gene Expression; 6.10.4 Comparison Between α-Tocopherol and TP; 6.11 Mechanistic Interpretation of TP Action; 6.12 Some In Vivo Applications of TP; 6.12.1 Effects of TP on Atherosclerosis and Inflammation; 6.12.2 Brain Effects of TP; 6.12.3 Effect of TP on Tumors
Additional Edition:
ISBN 9781788012409
Additional Edition:
Erscheint auch als Druck-Ausgabe VITAMIN E [Place of publication not identified], ROYAL Society OF CHEMISTR, 2019 ISBN 1788012402
Language:
English
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