Umfang:
1 Online-Ressource (VII, 187 p. 10 illus., 9 illus. in color)
Ausgabe:
2nd ed. 2019
ISBN:
9783030170868
Serie:
Springer eBooks
Inhalt:
Preface -- Chromatin regulation by long non-coding RNAs -- Regulation of Eukaryotic Cell Differentiation by Long Noncoding RNAs -- Roles of long non-coding RNAs in X-chromosome inactivation -- Roles of Long Non-Coding RNAs in Genomic Imprinting -- Dysregulation of long noncoding RNAs in human disease -- Functions of long non-coding RNAs in non-mammalian systems -- Emerging technologies to study long non-coding RNAs -- Long non coding RNAs and nuclear body formation and function -- The role of long non-coding RNAs in immunity -- Novel methods to study long non-coding RNAs -- OMICs of long non-coding RNAs -- Cancer epigenetics and long non-coding RNAs -- Roles of long non-coding RNAs in human development -- Index
Inhalt:
This second edition shows how long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity. So, while their function is not entirely clear, they may serve as key organizers of protein complexes that allow for higher order regulatory events. Advances in the field also include better characterization of human long non-coding RNAs, novel insights into their roles in human development and disease, their diverse mechanisms of action and novel technologies to study them
Weitere Ausg.:
ISBN 9783030170851
Weitere Ausg.:
Erscheint auch als Druck-Ausgabe ISBN 978-3-030-17085-1
Sprache:
Englisch
DOI:
10.1007/978-3-030-17086-8
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