UID:
almafu_9958355602702883
Format:
1 online resource (411p.):
,
Num figs.
Edition:
Reprint 2011
ISBN:
9783111503844
Note:
Frontmatter --
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PREFACE --
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ACKNOWLEDGEMENTS --
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CONTENTS --
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In Memoriam ALOIS NIEDERWIESER (1935 - 1987) --
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SECTION A: CHEMISTRY AND ANALYSIS OF PTERINS --
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HOMOGENEOUS CATALYTIC HYDROGENATION OF L-BIOPTERIN: INFLUENCE OF THE CHIRALITY OF THE SIDE CHAIN AND THE CATALYST ON ITS DIASTEREOSELECTIVE INDUCTION --
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SYNTHESIS OF D-NEOPTERIN-3'-PHOSPHATES --
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5-ALKYL-5.6.7.8-TETRAHYDROBIOPTERINS --
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MASS SPECTROMETRIC INVESTIGATIONS OF PTERIDINES --
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THE STRUCTURAL CHARACTERIZATION OF 6-PYRUVOYL TETRAHYDROPTERIN BY FAST ATOM BOMBARDMENT MASS SPECTROMETRY WITH ONE- AND TWO-DIMENSIONAL MASS ANALYSIS (FAB/MS AND FAB/MSMS) --
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SECTION Β: BIOCHEMISTRY AND METABOLISM OF PTERINS --
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TETRAHYDROBIOPTERIN: OTHER PHYSIOLOGICAL ROLES IN ADDITION TO AROMATIC AMINO ACID HYDROXYLATION? --
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1H-NMR STUDIES WITH TETRAHYDROBIOPTERINS, EVIDENCE FOR THE STRUCTURE OF 6-PYRUVOYLTETRAHYDROPTERIN, AN INTERMEDIATE IN THE BIOSYNTHESIS OF TETRAHYDROBIOPTERIN --
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PURIFICATION OF 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE FROM SALMON LIVER --
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PURIFICATION OF 6-PYRUVOYL TETRAHYDROPTERIN 2'-KETO REDUCTASE FROM HUMAN LIVER --
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HUMAN GTP CYCLOHYDROLASE I: PURIFICATION AND PREPARATION OF MONOCLONAL ANTIBODIES --
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DIHYDROMONAPTERIN TRIPHOSPHATE: OCCURRENCE, ANALYSIS, AND EFFECT ON TETRAHYDROBIOPTERIN BIOSYNTHESIS in vivo AND in vitro --
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BIOSYNTHESIS OF PTERIDINES AND DEAZA FLAVINS IN METHANOGENIC BACTERIA --
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TETRAHYDROBIOPTERIN BIOSYNTHESIS AND PTERIDINE METABOLISM IN CELLS OF THE BLOOD SYSTEM, LYMPHOID TISSUES AND IN BIOLOGICAL FLUIDS --
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MODIFIED PTERIPINE SYNTHESIS IN TRANSFORMED CELL LINES AND DURING HEAT SHOCK --
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DISEASE ASSOCIATED ALTERATIONS OF PTERIN BIOSYNIHESIS: ENHANCEMENT IN INFLAMMATORY DISEASE, HEMOPOIETIC REGENERATION AND ENDOTOXINEMIA --
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METABOLISM OF PTERINS IN THE CELLULAR IMMUNE SYSTEM OF MAN AND MOUSE --
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TETRAHYDROBIOPTERIN SYNTHESIS IS TRIGGERED BY INTERLEUKIN 2 BINDING AND MODULATES RECEPTOR AFFINITY --
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KINETICS OF PRODUCTION AND RELEASE OF NEOPTERIN. COMPARISON OF HUMAN PBMC WITH THE PERMANENT MONOCYTIC CELL LINE U937 AND ITS SUBCLONES. --
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SECTION D: PTERINS IN DIFFERENT DISEASES --
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VARIATIONS OF NEOPTERIN, DIHYDRONEOPTERIN AND IMMUNOLOGICAL PARAMETERS DURING PHYSICAL EXERCISE (JOGGING) --
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BIOPTERIN AND NEOPTERIN IN PLASMA AND LYMPHO-MONONUCLEAR BIOPTERIN IN GRAFT VERSUS HOST DISEASE AND INFECTION AFTER BONE MARROW TRANSPLANTATION. --
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EFFECTS OF ΡIRENZEPINE, ACICLOVIR AND TRIMETHOPRIM ON PTERINS IN BLOOD CELLS AND PLASMA --
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SECTION Ε: TETRAHYDROBIOPTERIN DEFICIENCIES --
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HETEROGENEITY OF TETRAHYDROBIOPTERIN DEFICIENCY --
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PRENATAL DIAGNOSIS OF TETRAHYDROBIOPTERIΝ DEFICIENCY --
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SEPIAPTERIN REDUCTASE IN HUMAN AMNIOCYTES, SKIN FIBROBLASTS, CHORIONIC VILLI AND STIMULATED MONONUCLEAR BLOOD CELLS. --
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IMPAIRED BIOPTERIN SYNTHESIS IN A PATIENT WITH MILD HYPERPHENYLALANINEMIA. A NEW VARIANT ? --
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DIHYDROPTERIDINE REDUCTASE ACTIVITY IN FETAL TISSUES --
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MOLECULAR ANALYSIS OF HUMAN DIHYDROPTERIDINE REDUCTASE AND DIHYDROPTERIDINE REDUCTASE DEFICIENCY --
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FATE OF PERIPHERALLY ADMINISTERED TETRAHYDROBIOPTERIΝ IN CONGENITAL TETRAHYDROBIOPTERIΝ DEFICIENCY --
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6-PYRUVOYL-TETRAHYDROPTERIN SYNTHASE DEFICIENCY: THERAPEUTIC TRIAL WITH TWO DIFFERENT SYNTHETIC PTERIN ANALOGUES IN THREE PATIENTS --
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PLACENTAL BARRIER IN MOTHER-TO-FETUS TRANSFER OF TETRAHYDROBIOPTERIN IN HUMANS --
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SECTION F: MONOAMINE NEUROTRANSMITTERS AND ENZYMES --
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THERAPEUTIC POTENTIAL OF TETRAHYDROBIOPTERIN THERAPY IN NEUROLOGICAL AND PSYCHIATRIC ILLNESS --
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ORGANIZATION OF THE CATALYTIC AND REGULATORY SITES OF RAT LIVER PHENYLALANINE HYDROXYLASE --
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IMMUNOCHEMICAL STUDIES OF PHENYLALANINE HYDROXYLASE --
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INFLUENCE OF SUBSTRATES AND COFACTORS ON TYROSINE HYDROXYLASE --
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MECHANISM OF ACTIVATION OF TRYPTOPHAN 5-MONOOXYGENASE BY MERCAPTIDES --
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EFFECTS OF TETRAHYDROPTERINS ON DOPA PRODUCTION IN VITRO AND IN VIVO --
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PTERINS AND MONOAMINE METABOLITES IN CEREBROSPINAL FLUID --
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AUTHOR INDEX --
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SUBJECT INDEX --
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LIST OF PARTICIPANTS
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In German.
Additional Edition:
ISBN 978-3-11-190547-1
Additional Edition:
ISBN 978-3-11-011341-9
Language:
German
DOI:
10.1515/9783111503844
URL:
https://doi.org/10.1515/9783111503844
URL:
https://doi.org/10.1515/9783111503844
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