UID:
edocfu_9958070433002883
Format:
1 online resource (262 p.)
ISBN:
3-318-00510-X
Series Statement:
Chemical immunology, vol. 76
Content:
Eosinophils represent approximately 1% of peripheral blood leukocytes and play a central proinflammatory and immunoregulatory role in various immune disorders. This volume provides the reader with a comprehensive survey of the major aspects of human eosinophilic biology and immunology as well as the most clinically relevant aspects of eosinophil-related disorders. Expert contributions cover the ultrastructural and phenotypic characteristics of human eosinophils, and their fundamental biochemical features including receptors for IgE and chemokines. The production of cytokines and their role in the activation of eosinophils are reviewed. Furthermore, the classic eosinophil-related disorders such as hypereosinophilia, drug reactions, allergic disorders and some cardiovascular diseases are described. Each of the chapters is written by an investigator actively engaged in research on the topic under consideration. The well-edited and stimulating material compiled in this volume will be of interest to all those working in allergology, immunology, biochemistry and pulmonary medicine.
Note:
Description based upon print version of record.
,
Ultrastructural analysis of human eosinophils -- Differentiation of human eosinophils -- The surface phenotype of human eosinophils -- IgE receptorts on human eosinophils -- Metabolism of lipid mediators in human eosinophils -- Inflammatory cell activation by eosinophil granule proteins -- Immunological interactions between human eosinophils and cardiac mast cells -- Eosinophil cytokines -- Expression of eosinophil-specific chemokines by human epithelial cells -- Activation of human eosinophils by chemokines -- Hypereosinophilic syndromes -- Eosinophilic disease of the skin.
,
English
Additional Edition:
ISBN 3-8055-6974-2
Language:
English
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