Format:
Online-Ressource
Edition:
Karger eBooks Collection 1997-2009
ISBN:
9783318011128
,
9783805577823
Series Statement:
World review of nutrition and dietetics 93
Content:
For the first time, international scientists describe the advances in genetics and nutrition by combining methods of molecular biology with those of functional genetics, also known as systems biology. This book provides the latest data on genetic variation and dietary response, nutrients and gene expression, and the contribution molecular biology has given to systems biology. It also includes a comprehensive critique of genetic association studies in defining the risk of chronic diseases and concludes that molecular diagnostic tests will eventually affect every area of health care from individual risk prediction, early diagnosis of disease, and determination of optimal treatment regimens, to monitoring treatment effectiveness. The appendix contains an extensive glossary of the newly emerging terminology, as well as recommendations for genetic screening.This publication is an essential tool for the future work of all physicians, nutritionists, dietitians, geneticists, physiologists, molecular biologists, anthropologists, food technologists, policy makers, ethicists and educators
Note:
First book to link these two emerging fields of research
,
""Contents""; ""Preface""; ""Genetic Variation: Nutritional Implications""; ""Heritability""; ""Genetic Diversity: Ethnic Differences and Gene Variants""; ""Genetic Variation, Dietary Sodium and the Response of Blood Pressure""; ""Genetic Variation, Omega�3 Fatty Acids and Inflammation""; ""Omega�6 and Omega�3 Fatty Acids and Prostaglandin Metabolism""; ""Omega�3 Fatty Acids, Genetic Variation and Cytokines""; ""Genetic Variation, Interleukin-6 and Cardiovascular Disease""; ""The Future of Genetic Nutrition: Nutrigenetics/Nutrigenomics""; ""The Potential for Novel Foods""
,
""Conclusions and Recommendations""""References""; ""Gene: Environment Interactions and Coronary Heart Disease Risk""; ""Coronary Heart Disease � An Example of a Complex Disorder""; ""Statistical Interaction versus Biological Interaction""; ""Gene: Environment Interaction and How to Analyse the Data""; ""Measuring Genetic and Environmental Factors""; ""Environmental Risk Factors""; ""Genetic Risk Factors""; ""Gene: Diet Interactions""; ""Impact of Smoking on Lipid Levels and CHD Risk""; ""APOE: Smoking Interaction and CHD Risk""
,
""Alcohol Consumption, Alcohol Dehydrogenase Gene and CHD Risk""""Conclusion""; ""Acknowledgement""; ""References""; ""Genes, Diet and Plasma Lipids: The Evidence from Observational Studies""; ""Gene by Diet Interactions""; ""Methodological Issues""; ""Dietary Assessment""; ""Genotyping and Quality Control Measures""; ""Levels of Interaction""; ""Gene-Diet Interactions Modulating Plasma Lipid Levels""; ""Familial Hypercholesterolemia""; ""Genes with Minor Effects but High Allele Frequencies""; ""Apolipoprotein A-I""; ""Apolipoprotein AP-IV (APOA4)""; ""Apolipoprotein CIII (APOC3)""
,
""Apolipoprotein E""""Hepatic Lipase""; ""Peroxisome Proliferator-Activated Receptor-gamma""; ""5-Lipoxygenase (ALOX5)""; ""Conclusions""; ""Acknowledgements""; ""References""; ""Dynamic Relationships between the Genome and Exposures to Environments as Causes of Common Human Diseases""; ""The Problem""; ""Disease Susceptibility""; ""Population Genetics""; ""Two Different Research Strategies for Studying Genetic Architecture""; ""Disease Is a 'Simple' Consequence of Variations in Independent Causal Agents""; ""Disease Is a Consequence of the 'Complex' Organization of Interacting Agents""
,
""Conclusions""""Acknowledgments""; ""References""; ""Achieving Balance in the Omega� 6/ Omega� 3 Ratio through Nutrigenomics""; ""Methods""; ""Construction of Expression Vectors""; ""Production of Transgenic Mice""; ""Animal Feeding""; ""Lipid Analysis""; ""Results""; ""Discussion""; ""Acknowledgements""; ""References""; ""Nutrients and Gene Expression""; ""Direct and Indirect Regulation of Gene Expression by Nutrients in Simple and Complex Organisms""; ""Nutrients as Ancestral Modulators of Gene Expression""; ""Examples of Nutrient Control of Gene Expression""; ""Amino Acids""
,
""Nucleotides""
Additional Edition:
ISBN 9783805577823
Language:
English
Subjects:
Medicine
Keywords:
Genetik
;
Ernährung
;
Genetik
;
Ernährungskrankheit
;
Genetik
;
Umwelt
;
Krankheit
Author information:
Simopoulos, Artemis P. 1933-
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