UID:
almahu_9947364683402882
Format:
X, 222 p.
,
online resource.
ISBN:
9783540330493
Series Statement:
Topics in Organometallic Chemistry, 17
Content:
Bioorganometallic Chemistry has become a mature area of science and is comprehensively covered by leading experts in this book. Naturally occuring bioorganometallic complexes, such as vitamin B12 and recently discovered iron and nickel hydrogenases, including a possible role of the latter in the geochemical theory of the origin of life, are considered. The possible formation of carbene complexes of cytochrome P450 enzymes in various metabolisms of xenobiotics is also discussed. The bioorganometallic chemistry is considered to provide not only organometallic receptors such as polynuclear organometallic macrocycles for biologically interesting molecules but also ferrocene-peptide bioconjugates giving a peptidomimetic basis for protein folding. The medicinal properties of organometallic compounds are reviewed, with notable applications in the treatment and diagnosis of cancer and in the treatment of viral, fungal, bacterial and parasitic infections. Therefore the reader will get a balanced view of this rapidly developing and promising area.
Note:
Bernhard Kräutler: Biological Organometallic Chemistry of Vitamin B12 -- Juan C. Fontecilla-Camps: Bioorganometallic chemistry of iron-nickel clusters in enzymes -- Gérard Simonneaux: Bioorganometallic Chemistry of Metalloporphyrins -- Kay Severin: Synthetic Organometallic Hosts for Biologically Interesting Molecules -- Toshikazu Hirao: Peptide Supramolecular Systems with Metallocene derivatives -- Paul Dyson: Medicinal Properties of Organometallic Compounds.
In:
Springer eBooks
Additional Edition:
Printed edition: ISBN 9783540330479
Language:
English
Subjects:
Chemistry/Pharmacy
Keywords:
Aufsatzsammlung
;
Aufsatzsammlung
URL:
http://dx.doi.org/10.1007/b97910
URL:
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