Umfang:
Online-Ressource
,
v.: digital
Ausgabe:
Online-Ausg. Springer eBook Collection. Biomedical and Life Sciences Electronic reproduction; Available via World Wide Web
ISBN:
9783642043000
Serie:
Research and Perspectives in Alzheimer's Disease
Inhalt:
This volume brings together experts from basic and clinical science to provide a broad survey of the role of insulin in the brain, and to discuss the mechanisms through which insulin dysregulation contributes to the development of cognitive impairment and late-life neurodegenerative disease. Each author has greatly furthered our understanding of the relationships among insulin, diabetes, and Alzheimer's disease, moving us far beyond the belief that the brain is an insulin-insensitive organ. Given the recent pandemic of conditions associated with insulin resistance, it is imperative that we ach
Anmerkung:
Includes bibliographical references and index
,
FM; 1; Insulin Action in the Brain and the Pathogenesis of Alzheimer´s Disease; The Insulin Signaling System; Linking the Receptor to the Insulin and IGF-1 Signaling Pathways; Regulation of the IRS and IGF-1 Receptors in Physiology and Pathophysiology; Creation and Characterization of the Brain IR Knockout Mouse
,
Impairment of insulin Signaling in Brain is Linked to Neurodegenerative DiseaseInsulin-degrading Enzyme in Pathogenesis of Alzheimer´s Disease and Metabolic Diseases; Insulin, Diabetes, and Brain Cholesterol Metabolism; References; 2; The Brain-insulin Connection, Metabolic Diseases and Related Pathologies; Introduction; Central Interplay of Insulin with Hormones, Neuropeptides and Neurotransmitters; Mechanisms of Action; Metabolic, Mood and Neurodegenerative Pathologies; Current treatment trends; Conclusion
,
Electronic reproduction; Available via World Wide Web
Weitere Ausg.:
ISBN 9783642042997
Weitere Ausg.:
Buchausg. u.d.T. Diabetes, insulin and Alzheimer's disease Berlin : Springer, 2010 ISBN 9783642042997
Weitere Ausg.:
ISBN 3642042996
Sprache:
Englisch
Fachgebiete:
Medizin
Schlagwort(e):
Alzheimerkrankheit
;
Diabetes mellitus
;
Insulin
;
Aufsatzsammlung
DOI:
10.1007/978-3-642-04300-0
URL:
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